Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Homo sapiens]
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Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Stable identifierREACT_1504.3
AuthoredD'Eustachio, P, 2004-01-13
ReviewedHe, L, 2010-05-10
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The plasma membrane-associated protein SLC28A3 mediates the transport of one molecule of adenosine, cytidine, guanosine, inosine, thymidine, or uridine, and two sodium ions, from the extracellular space to the cytosol. [Ritzel et al 2001]
Input (present at start of reaction)ligands of SLC28A3 [extracellular region]
sodium ion [extracellular region] CCP x 2
Output (present at end of reaction)ligands of SLC28A3 [cytosol]
sodium ion [cytosol] CCP x 2
CatalystSLC28A3 [plasma membrane] UKEGBCdRHUR
GO molecular functionnucleoside:sodium symporter activity GO
OrganismHomo sapiens
Cellular compartmentplasma membrane GO
References

Ritzel, MW, Ng, AM, Yao, SY, Graham, K, Loewen, SK, Smith, KM, Ritzel, RG, Mowles, DA, Carpenter, P, Chen, XZ, Karpinski, E, Hyde, RJ, Baldwin, SA, Cass, CE, Young, JD Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib) 2001 J Biol Chem PubMed

Equivalent event(s) in other organism(s)Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Canis familiaris]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Bos taurus]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Sus scrofa]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Mus musculus]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Rattus norvegicus]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Gallus gallus]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Taeniopygia guttata]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Xenopus tropicalis]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Drosophila melanogaster]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Caenorhabditis elegans]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Escherichia coli]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 [Staphylococcus aureus N315]
Participating molecules
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Date: 2010-09-02 22:12:42
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