Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Homo sapiens]
Reactionmap
Click on the map:shifts focuszooms inzooms out
Diagram
Details
open to selected event open all close all
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Stable identifierREACT_2011.3
AuthoredD'Eustachio, P, 2004-01-13
ReviewedHe, L, 2010-05-10
Your feedbackLet us know what you think of this article (click here)
The plasma membrane-associated protein SLC28A2 mediates the transport of one molecule of adenosine, guanosine, inosine, or uridine, and one sodium ion, from the extracellular space to the cytosol. [Loewen et al 1999, Wang et al 1997]
Input (present at start of reaction)ligands of SLC28A2 [extracellular region]
sodium ion [extracellular region] CCP
Output (present at end of reaction)ligands of SLC28A2 [cytosol]
sodium ion [cytosol] CCP
CatalystSLC28A2 [plasma membrane] UKEGBCdORHUR
GO molecular functionnucleoside:sodium symporter activity GO
OrganismHomo sapiens
Cellular compartmentplasma membrane GO
References

Wang, J, Su, SF, Dresser, MJ, Schaner, ME, Washington, CB, Giacomini, KM Na+-dependent purine nucleoside transporter from human kidney: cloning and functional characterization 1997 Am J Physiol Renal Physiol PubMed

Loewen, SK, Ng, AM, Yao, SY, Cass, CE, Baldwin, SA, Young, JD Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na+ nucleoside cotransporters hCNT1 and hCNT2 1999 J Biol Chem PubMed

Equivalent event(s) in other organism(s)Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Bos taurus]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Sus scrofa]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Mus musculus]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Rattus norvegicus]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Gallus gallus]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Taeniopygia guttata]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Xenopus tropicalis]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Danio rerio]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Drosophila melanogaster]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Caenorhabditis elegans]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Escherichia coli]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Staphylococcus aureus N315]
Participating molecules
[Change default viewing format] [SBML] [BioPAX2] [BioPAX3] [PDF] [Protégé] [SVG]

Stable link for this page

Date: 2010-09-02 22:13:15
Help