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name	guanyl-nucleotide exchange factor activity
Accession	GO
Definition	Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Molecules/complexes with this activity
A2VDX3 [Golgi membrane] UKE Active Trk receptor:Frs3:Crk:C3G [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] Active TrkA receptor:Phospho-ARMS:Crk:C3G complex (name copied from entity in Homo sapiens) [plasma membrane] ... List all 353 items
Reactions catalysed by this activity
(Frs2)C3G stimulates nucleotide exchange on Rap1 [Homo sapiens] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Canis familiaris] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Bos taurus] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Sus scrofa] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Mus musculus] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Gallus gallus] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Taeniopygia guttata] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Xenopus tropicalis] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Danio rerio] (Frs2)C3G stimulates nucleotide exchange on Rap1 [Caenorhabditis elegans] ... List all 411 items
Is a specialisation of activities
GTPase regulator activity GO nucleoside-triphosphatase regulator activity GO enzyme regulator activity GO molecular_function GO
Is a generalisation of more specialised activities
ARF guanyl-nucleotide exchange factor activity GO Ras guanyl-nucleotide exchange factor activity GO