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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
Surnamede Bono
First nameBernard
InitialsB
AffiliationEBI
Author of summation(s)
A hallmark of human NK cells is the expression of HLA class ...
A number of MHC Class I molecules a known bind differentiall...
A number of receptors and cell adhesion molecules play a key...
Activation of phospholipase C enzymes results in the generat...
After cleavage of C5, C5b undergoes conformational changes a...
After interaction with its ligand HLA-E, which is expressed ...
Alpha5beta1 integrin was the first integrin shown to bind fi...
Although JAM-C is better known for its interaction with MAC-...
Apart from its well-established interaction with VLA-4, JAM-...
C1 activation requires interaction with two separate Fc doma...
C1 is a calcium-dependent complex of C1q, R and S in the mol...
C1, the first component of complement is a complex containin...
C2 is cleaved into the large C2a and the small C2b fragment....
C3(H2O):Factor Bb is a C3 convertase, sometimes referred to ...
C3b on a surface binds Factor B from solution to form a comp...
C3b:Bb is naturally labile with a half-life of ~90 s; associ...
C4 alpha chain has a thioester bond between Cys 1010 and Gln...
C4b and C2a form a complex termed the classical pathway C3 c...
CD160 is a GPI-anchored lymphocyte surface receptor in which...
CD177 is a 58- to 64-kDa glycosylphosphatidylinositol-anchor...
CD19 is a lymphocyte cell surface molecule that functions as...
CD2, CD48, CD84, CD244 and CD58 have a similar extracellular...
CD40 is a member of the Tumour Necrosis Factor receptor fami...
CD84 is a homophilic receptor expressed on T cells, B cells,...
Circulates in blood as a disulfide-linked trimer of an alpha...
Cleavage of C5 by C5 convertases is the last enzymatic step ...
Complement activation is due to a cascade of proteolytic ste...
CpG DNA is an unusual Pathogen-Associated Molecular Pattern ...
Dissociation from the activated receptor quickly follows pho...
Dominant mutations in the fibroblast growth factor receptor ...
eIF4B is a physiologically relevant target of S6K1. Once pho...
Endosomal recognition of influenza genomic RNA and imidazoqu...
Factor D, a constitutively active serine protease found in t...
Factor D, a constitutively active serine protease found in t...
FGF23 is a member of the endocrine subfamily of FGFs. It is ...
FGFR3 is a receptor tyrosine kinase of the FGF receptor fami...
FGFR4 is expressed mainly in mature skeletal muscle, and dis...
First, IRAK1 is phosphorylated at Thr209 by IRAK4. This resu...
Fragments of extracelllar flagellin bind the TLR5 homodimer.
FRS2alpha is activated through tyrosine phosphorylation cata...
FRS2beta is activated through tyrosine phosphorylation catal...
Grb2 bound to tyrosine phosphorylated FRS2 forms a ternary c...
Hemostasis is a physiological response that culminates in th...
In this irreversible reaction, the activated C1r subunit of ...
In this reaction, FGF receptor in the plasma membrane binds ...
In view of the highly variable nature of T-cell receptors, t...
Initiation of platelet adhesion is the first step in the for...
Integrin-associated protein (IAP or CD47) is a receptor for ...
Integrins play a central role in mediating lymphocyte adhe...
IRAK4 is the mammalian homolog of Drosophila melanogaster Tu...
JAM members, such as JAML, bind coxsackie and adenovirus re...
JAM-A is the most widely expressed member of the family, and...
JAM-A plays a key role in leukocyte transmigration and infla...
JAM-B and -C bind each other and are strongly expressed by e...
JAM-C has been detected in epithelial-cell desmosomes. JAM-C...
L-selectin plays a major role in leukocyte traffic through l...
LBP delivers LPS from bacteria (or bacterial membrane fragme...
Leukocyte extravasation is a rigorously controlled process t...
Leukocyte immunoglobulin (Ig)-like receptors [LILRs, also kn...
Linked by disulphide bond between positions 559 and 816.
Lipopolysaccharide-binding protein (LBP) is a ~60-kDa serum ...
Little is known about TLR10 ligands. It has been established...
Mannose-binding lectin (MBL) and ficolins (Ficolin-1, Ficoli...
MBL or ficolins binding to carbohydrates on the target surfa...
MerTK appears to be required for ingestion of apoptotic cell...
Microbal stimulation was shown to alter mRNA expression of T...
Most cells of the immune system express receptors for the Fc...
mTOR forms a functional protein complex with at least two pr...
Mucosal addressin cell adhesion molecule (MADCAM1) is presen...
MyD88 binds to IRAK (IL-1 receptor-associated kinase) and th...
MyD88-independent signaling pathway is shared by TLR3 and TL...
NK cells express adhesion molecules that allow interaction w...
NKG2D is an activating immunoreceptor. By engaging NKG2D, Hl...
Once phosphorylated, S6K1-P phosphorylates and activates rib...
Phospholipase C-gamma (PLC-gamma) is a substrate of the fibr...
Phosphorylation of eEF2 kinase by S6K1-P results in decrease...
Phosphorylation of TSC2 by PKB disrupts TSC1/TSC2 heterodime...
PKB and PDK1 are activated via membrane-bound PIP3. Activate...
Platelet activation begins with the initial binding of adhes...
PLC gamma is phosphorylated by activated FGFR, resulting in ...
PSGL-1 is expressed as a homodimer of two 120-kDa subunits t...
Raptor recruits mTOR to non-phosphorylated 4E-BP1 bound to e...
Recruitment of monocytic cells to the vessel wall by platele...
Recruitment of PLC-gamma by FGF receptors has been best stud...
Rheb is a GTP binding protein that exhibits GTPase activity....
RNA can serve as a danger signal, both in its double-strande...
S6K1 contains a TOS motif. mTORC1 requires an intact TOS mot...
Second, Thr387 in the activation loop is phosphorylated, lea...
Several key IgSF cell adhesion molecules engage integrin and...
Signaling via FGFRs is mediated via direct recruitment of si...
Studies have mapped 8 tyrosine residues in the cytoplasmic d...
Synthetic oligodeoxynucleotides (ODN) expressing non-methyla...
T cells distinguish foreign material from self through prese...
The 22 members of the fibroblast growth factor (FGF) family ...
The 3 pathways of complement activation converge on the clea...
The ability of growth factors to protect from apoptosis is p...
The alpha chain of C4 is cleaved, releasing an N-terminal po...
The complex of C3b:Factor Bb, stabilized on the cell surface...
The crystal structure of the human CD2-CD58 complex also sho...
The FGFs are a family of 22 secreted glycoproteins that are ...
The first known downstream component of TLR4 and TLR2 signal...
The FRS family of scaffolding adaptor proteins has two membe...
The lectin-like NK cell receptor KLRG1 binds to cadherins on...
The lectin-like oxidized low density lipoprotein receptor- 1...
The MBL polypeptide chain consists of a short N-terminal cys...
The phospho-tyrosine positions for FRS2-beta were inferred b...
The presence of CEACAM dimers was shown to lead to an increa...
The proteins participating in alternative pathway activation...
The tethering of platelets to the site of vascular injury is...
The thioester linkage between cysteine residue 1010 and glut...
The Toll-like receptor 4 (TLR4) is a membrane-spanning prote...
The triggering receptor expressed on myeloid cells 1 (TREM-1...
The two MASP2 fragments are linked via a disulphide bond bet...
The vertebrate fibroblast growth factor receptor 1 (FGFR1) i...
Thioester bond hydrolysis causes conformational rearrangemen...
This pathway depicts the binding of an experimentally-verifi...
This pathway depicts the binding of an experimentally-verifi...
This pathway depicts the binding of an experimentally-verifi...
This pathway depicts the binding of an experimentally-verifi...
This pathway depicts the binding of an experimentally-verifi...
This pathway depicts the binding of an experimentally-verifi...
TLR1 is expressed by monocytes. TLR1 and TLR2 cotranslationa...
TLR2 and TLR4 recognize different bacterial cell wall compon...
TLR2 is involved in recognition of peptidoglycan from gram-p...
TLR4 is unique among the TLR family in its ability to recrui...
TLR5 is the receptor for flagellin, the protein that forms b...
TLR9 signaling has the uncommon property of triggering PI3K-...
Toll-like Receptor 4 is a Microbe Associated Molecular Patte...
TRAF6 binding to MAPK kinase kinase 1 (MEKK1) is mediated by...
TRIF (TICAM1) mediates the MyD88-independent pathway from TL...
TRIF-related adapter molecule (TRAM, also called TIRP or TIC...
Tyrosine phosphorylation of SHP2 by FGFR kinase is required ...
UniProt identifiers for both variable and constant portions ...
While not ubiquitously distributed, CD200 is expressed on a ...
Author of entries
'ECSIT [cytosol]' is required for 'TRAF6 binds MEKK1'
'EEA1:EEA1 [endosome membrane]' positively regulates 'Engulfed CpG DNA binds to endosomal TLR9'
'Heparan Sulphate [extracellular region]' is required for 'FGFR1b binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR1c binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR1c binds to Klotho-bound FGF23'
'Heparan Sulphate [extracellular region]' is required for 'FGFR2b binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR2c binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR3b binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR3c binds to FGF'
'Heparan Sulphate [extracellular region]' is required for 'FGFR4 binds to FGF'
'Heparan Sulphate [extracellular region]' positively regulates 'Basigin binds CyPA'
'Heterdimerization of CEACAMs' positively regulates 'Integrin alpha5beta1 binds FN1 dimer'
'Inhibition of TSC complex formation by PKB' positively regulates 'GTP loading by Rheb'
'IRAK-M [cytosol]' negatively regulates 'Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:Mal:p-IRAK4 complex'
'JAM-B binds JAM-C' positively regulates 'Integrin alpha4beta1 binds JAM2'
'LRIG1 [plasma membrane]' negatively regulates 'EGFR binds EGF ligand'
'Platelet Factor 4 [extracellular region]' positively regulates 'protein C -> activated protein C + protein C heavy chain activation peptide'
'Rab5 [endosome membrane]' is required for 'Rab5-mediated recruitment of class III PI3K to TLR9'
'RP105:MD1 [plasma membrane]' negatively regulates 'Transfer of LPS onto TLR4'
'SIGRR [plasma membrane]' negatively regulates 'MyD88 forms a complex with MAL:activated TLR2/4'
/figures/GPIIbII3inside_out.png
/figures/GPIIbII3Integrin-MAPK.png
/figures/GPIIbII3Integrin-MAPK.png
/figures/hm_plt_adhesion.jpg
/figures/hm_plt_response_to_ca.jpg
/figures/immune_synapse_figure_1.jpg
/figures/integrin_signaling.png
/figures/mono-plt-endo.jpg
/figures/plateletactivation.jpg
11xCbxE-GAS6(39-691) [extracellular region] UKENBCdOGUPPDD
11xCbxE-PROS1 [extracellular region] UKENBCdORHGURPD
2xN4GlycoAsn-LY96 [plasma membrane] UKENBCdORHGURPD
2xN4GlycoAsn-TLR4 [plasma membrane] UKENBCdORHGUR
3',5'-cyclic-nucleotide phosphodiesterase activity of Phosphorylated PDE3B [cytosol]
5HT [extracellular region] CCP
A2M [platelet alpha granule lumen] UKENBCdORHGURPD
Activated C1R [extracellular region]
Activated C1S [extracellular region]
Activated C1S:activated C1R tetramer [extracellular region]
Activated conventional protein kinase C [plasma membrane]
Activated FGFR [plasma membrane, extracellular region]
Activated FGFR and FRS2 bind to SHP2 [Homo sapiens]
Activated FGFR binds PLC-gamma [Homo sapiens]
Activated FGFR bound to activated PLC gamma [plasma membrane]
Activated FGFR bound to PI3K [plasma membrane]
Activated FGFR bound to PLC gamma [plasma membrane]
Activated FGFR1b homodimer [plasma membrane]
Activated FGFR1c homodimer [plasma membrane]
Activated FGFR2b long homodimer [plasma membrane]
Activated FGFR2c long homodimer [plasma membrane]
Activated FGFR3b homodimer [plasma membrane]
Activated FGFR3c homodimer [plasma membrane]
Activated FGFR4 homodimer [plasma membrane]
Activated FGFR:FRS2beta [plasma membrane]
Activated FGFR:p-FRS2-alpha:p-SHP2 [plasma membrane]
Activated FGFR:p-FRS2alpha [plasma membrane]
Activated FGFR:p-FRS2beta [plasma membrane]
Activated MASP-1 dimer [extracellular region]
Activated MASP-2 dimer [extracellular region]
Activated mTORC1 [cytosol]
Activated PI3K [plasma membrane, endosome membrane, cytosol]
Activated PKC alpha [plasma membrane]
Activated PKC beta [plasma membrane]
Activated PLC gamma release by activated FGFR [Homo sapiens]
Activated Rac1:PI3K alpha [cytosol]
Activated TLR1:2 or TLR 2:6 heterodimers or TLR4 homodimer [plasma membrane]
Activated TLR4 signalling [Homo sapiens]
activated TLR9:PI3K class III [endosome membrane]
Activation of C1R [Homo sapiens]
Activation of C1S [Homo sapiens]
Activation of C3 and C5 [Homo sapiens]
Activation of C5 [Homo sapiens]
Activation of conventional Protein Kinase C [Homo sapiens]
Activation of MASPs [Homo sapiens]
Activation of PKB [Homo sapiens]
Activation of S6K1 [Homo sapiens]
ACTN4 [platelet alpha granule lumen] UKENBCdOORHGURPPDD
Adhesion of integrin alphaIIbbeta3 to fibrin network [Homo sapiens]
ADORA3 [plasma membrane] UKENBCdORHGURPD
ADP [extracellular region] CCP
ADP [platelet dense granule lumen] CCP
AGER [plasma membrane] UKEEENBCdORHGURPD
AKT2 [cytosol] UKENBCdORHGURPPPPPPPDDDDDDD
ALB(19-609) [extracellular region] UKENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
ALCAM [plasma membrane] UKENBCdORHGURPD
Alpha IIb Beta 3 Integrin [platelet alpha granule membrane]
Alternative complement activation [Homo sapiens]
AMICA1 [plasma membrane] UKENBCdORHGUR
Antigen [plasma membrane]
Antigen peptide bound class I MHC [plasma membrane]
Antigen-antibody complex [plasma membrane]
Antigen-bound antibody bound to lymphoid Fc gamma receptors [plasma membrane]
Antigen-bound Ig G Antibody [extracellular region]
Antigen: antibody: C1 (activated C1R and C1S) complex [plasma membrane]
Antigen: antibody: C1 (activated C1R) complex [plasma membrane]
Antigen: antibody: C1 complex [plasma membrane]
APP(18-770) [platelet alpha granule lumen] UKENBCdOOOORHGURPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
ARHGEF1 [cytosol] UKENBCdORRHHGURRPPDD
Association of LBP with LPS [Homo sapiens]
Autocatalytic phosphorylation of FGFR1b [Homo sapiens]
Autocatalytic phosphorylation of FGFR1c [Homo sapiens]
Autocatalytic phosphorylation of FGFR2b [Homo sapiens]
Autocatalytic phosphorylation of FGFR2c [Homo sapiens]
Autocatalytic phosphorylation of FGFR3b [Homo sapiens]
Autocatalytic phosphorylation of FGFR3c [Homo sapiens]
Autocatalytic phosphorylation of FGFR4 [Homo sapiens]
Autocatalytic phosphorylation of Klotho-bound FGFR1c [Homo sapiens]
AXL [plasma membrane] UKENBCdORHGURPD
Bacterial mannose-based carbohydrate surface pattern [plasma membrane]
Basigin binds CyPA [Homo sapiens]
Basigin binds MCT1, MCT3 and MCT4 [Homo sapiens]
Basigin bound to CD43 [plasma membrane]
Basigin bound to CyPA [plasma membrane]
Basigin bound to MCTs [plasma membrane]
Basigin homodimer [plasma membrane]
Basigin homodimerises [Homo sapiens]
Basigin interacts with CD43 [Homo sapiens]
Betaproteobacteria
Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen [Homo sapiens]
Binding of IP3 to IP3 receptor [Homo sapiens]
Binding of Syk tyrosine kinase [Homo sapiens]
BOC-1 [plasma membrane] UKENBCdORHGUR
BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 [Homo sapiens]
BSG [Golgi membrane] UKENBCdOORHGURR
BSG [plasma membrane] UKENBCdOORHGURR
BSG:Integrin alpha3beta1, alpha6beta1 [plasma membrane]
BTK [cytosol] UKENBCdOORHGURPPPPPPPDDDDDDD
BTLA [plasma membrane] UKENBCdORHGURPD
C1 complement factor (with activated C1R and C1S) [extracellular region]
C1 complement factor (with activated C1R) [extracellular region]
C1 complement factor [extracellular region]
C1Q [extracellular region]
C1Q subunit (C1QA:C1QB:C1QC heterotrimer) [extracellular region]
C1QA [extracellular region] UKENBCdORHGURPD
C1QB [extracellular region] UKENBCdORHGURPD
C1QC [extracellular region] UKENBCdORHGURPD
C1R C-terminal fragment [extracellular region] UKGU
C1R N-terminal fragment [extracellular region] UKGU
C1R(18-705) [extracellular region] UKGU
C1S C-terminal fragment [extracellular region] UKENBCdORRHHGURRPPDD
C1S N-terminal fragment [extracellular region] UKENBCdORRHHGURRPPDD
C1S(16-688) [extracellular region] UKENBCdORRHHGURRPPDD
C1S:activated C1R tetramer [extracellular region]
C1S:C1R tetramer [extracellular region]
C2 [extracellular region] UKEEENBCdORHGUR
C2a [extracellular region] UKEEENBCdORHGUR
C2b [extracellular region] UKEEENBCdORHGUR
C3 alpha chain [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
C3 beta chain [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
C3 convertases [plasma membrane, extracellular region]
C3(H2O) [extracellular region]
C3(H2O):Bb [extracellular region]
C3(H2O):CFB [extracellular region]
C3(H2O):Factor Bb cleaves C3 to C3b and C3a [Homo sapiens]
C3a [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
C3b [extracellular region]
C3b alpha' [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
C3b:Bb:C3b:Properdin [plasma membrane]
C3d complexed with antigen [extracellular region]
C3d fragment [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
C3d-complexed antigen binds to complement receptor [Homo sapiens]
C4 activator [plasma membrane]
C4 alpha [extracellular region] UKKENBCdOOORHGURPD
C4A alpha b [extracellular region] UKKENBCdOOORHGURPD
C4A beta [extracellular region] UKKENBCdOOORHGURPD
C4A gamma [extracellular region] UKKENBCdOOORHGURPD
C4A-derived C4a [extracellular region] UKKENBCdOOORHGURPD
C4b:C2a:C3b [plasma membrane]
C5 alpha [extracellular region] UKENBCdOORHGURPPPDDD
C5 beta [extracellular region] UKENBCdOORHGURPPPDDD
C5 convertases [plasma membrane]
C5a [extracellular region] UKENBCdOORHGURPPPDDD
C5b [extracellular region]
C5b alpha' [extracellular region] UKENBCdOORHGURPPPDDD
C5b:C6 complex [extracellular region]
C5b:C6:C7 complex [extracellular region]
C5b:C6:C7 complex [plasma membrane]
C5b:C6:C7:C8 complex [plasma membrane]
C6 [extracellular region] UKENBCdORHGUR
C7 [extracellular region] UKENBCdOORHGUR
C7 allows complex to insert into membrane under attack [Homo sapiens]
C8 [extracellular region]
C8A [extracellular region] UKENBCdORHGUR
C8B [extracellular region] UKENBCdORHGUR
C8G [extracellular region] UKENBCdORHGURPPDD
C9(22-559) [extracellular region] UKENBCdORHGUR
Ca2+ [platelet dense granule lumen] CCP
Ca2+ [platelet dense tubular network lumen] CCP
Ca2+ [platelet dense tubular network membrane] CCP
CADM3 [plasma membrane] UKEOGUPD
calcium channel activity of IP3 receptor bound to IP3 and Ca++ [platelet dense tubular network membrane]
calcium channel activity of P2X1 purinoreceptor bound to ATP [plasma membrane]
calcium-dependent protein kinase C activity of Activated conventional protein kinase C [plasma membrane]
CAV1 [Golgi membrane] UKENBCdORHGUR
Caveolin-1 binds Basigin [Homo sapiens]
Caveolin-1 bound to Basigin [Golgi membrane]
CBL [cytosol] UKENBCdORHGURPPPPDDDD
CBL [plasma membrane] UKENBCdORHGURPPPPDDDD
CD14 [plasma membrane, extracellular region]
CD14(20-345) [extracellular region] UKENBCdORRHHGURR
CD160 [plasma membrane] UKENBCdORHGUR
CD177 [plasma membrane] UKGU
CD177 binds PECAM-1 [Homo sapiens]
CD180 [plasma membrane] UKENBCdORHGUR
CD19 [plasma membrane] UKENBCdORHGUR
CD2 [plasma membrane] UKENBCdORHGURPPPPPPDDDDDD
CD200 [plasma membrane] UKEOGU
CD200 binds to CD200R [Homo sapiens]
CD200 bound to CD200R [plasma membrane]
CD200R1 [plasma membrane] UKENBCdORRHHGURR
cd21(1-?) [plasma membrane] UGU
CD226 [plasma membrane] UKENBCdORHGUR
CD226 bound to Nectin 2 [plasma membrane]
CD226:PVR [plasma membrane]
CD244 [plasma membrane] UKEOGU
CD247-1 [plasma membrane] UKENBCdOORHGURPPDD
CD28 homodimer [plasma membrane]
CD3 epsilon delta [plasma membrane]
CD3 epsilon gamma [plasma membrane]
CD34-1 [plasma membrane] UKENBCdORHGUR
CD36 [platelet alpha granule membrane] UKENBCdOOORRRHHHGURRR
CD3D [plasma membrane] UKENBCdOORHGURPD
CD3E [plasma membrane] UKENBCdORHGURPPPDDD
CD3G [plasma membrane] UKENBCdORHGURPD
CD40 complexed with CD40L [plasma membrane]
CD40 interacting with CD40L [Homo sapiens]
CD40-1 [plasma membrane] UKENBCdOORHGURPPPPPDDDDD
CD40LG(1-261) [plasma membrane] UKENBCdOORHGURPPDD
CD47 [plasma membrane] UKENBCdORHGUR
CD47 binds SIRP [Homo sapiens]
CD47 bound to its ligand [plasma membrane]
CD47-binding SIRPs [plasma membrane]
CD48 [plasma membrane] UKENBCdORHGUR
CD48 binds CD244 [Homo sapiens]
CD48 bound to CD244 [plasma membrane]
CD58 [plasma membrane] UKENBCdORHGURPPDD
CD58 binds CD2 [Homo sapiens]
CD58 bound to CD2 [plasma membrane]
CD63 [plasma membrane] UKENBCdORRHHGURR
CD72 [plasma membrane] UKENBCdORHGUR
CD79A [plasma membrane] UKENBCdORHGUR
CD79B [plasma membrane] UKENBCdORHGUR
CD8 [plasma membrane]
CD80 (B7-1) homodimer [plasma membrane]
CD80 [plasma membrane] UKENBCdORHGURPPDD
CD81 [plasma membrane] UKENBCdORHGURPPDD
CD84 dimer [plasma membrane]
CD84 homodimerises [Homo sapiens]
CD86 [plasma membrane] UKENBCdORHGURRPPDD
CD8A [plasma membrane] UKENBCdOORHGURPPPDDD
CD9 [platelet alpha granule membrane] UKENBCdORHGUR
CD96 [plasma membrane] UKENBCdORHGUR
CD96 binds PVR [Homo sapiens]
CD96:PVR [plasma membrane]
CDH1(155-882) [plasma membrane] UKENBCdOOORHGURPD
CDH12 [plasma membrane] UKENBCdORRRRRHGUR
CDH2 [plasma membrane] UKENBCdORHGUR
CDH3 [plasma membrane] UKENBCdOOORHGUR
CDON [plasma membrane] UKENBCdOGU
CEACAM heterodimer [plasma membrane]
CEACAM1 [plasma membrane] UKENBCdORHGUR
CEACAM6 [plasma membrane] UKENBCdORHGUR
CEACAM8 [plasma membrane] UKENBCdORHGUR
Cell surface interactions at the vascular wall [Homo sapiens]
Cell surface:C3b:Bb [plasma membrane]
Cell surface:C3b:Bb:Properdin [plasma membrane]
Cell surface:C3b:CFB [plasma membrane]
Cell surface:C4b:C2a [plasma membrane]
CFB(26-259) [extracellular region] UKEENBCdORHGURPPPPPDDDDD
CFB(26-764) [extracellular region] UKEENBCdORHGURPPPPPDDDDD
CFB(260-764) [extracellular region] UKEENBCdORHGURPPPPPDDDDD
CFB(260-764) [plasma membrane] UKEENBCdORHGURPPPPPDDDDD
CFD [platelet alpha granule lumen] UKENBCdORHGURPPPPPPPDDDDDDD
CFP [extracellular region] UKENBCdOORHGURPPDD
Chlamydia
Chlamydia trachomatis
Chlamydiaceae
Chlamydiae
Chlamydiae (class)
Chlamydiae/Verrucomicrobia group
Chlamydiales
class I MHC B13 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B14 [plasma membrane] UEOGUPPPPPPPDDDDDDD
class I MHC B15 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B18 [plasma membrane] UKENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B27 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B35 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B37 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B38 [plasma membrane] UEOGUPPPPPPPDDDDDDD
class I MHC B39 [plasma membrane] UEOGUPPPPPPPDDDDDDD
class I MHC B40 [plasma membrane] UENBCdOOOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
class I MHC B41 [plasma membrane] UEOGUPPPPPPPDDDDDDD
class I MHC B42 [plasma membrane] UENBCdORHGUR
Classical antibody-mediated complement activation [Homo sapiens]
Cleavage of C3 by C3 convertases [Homo sapiens]
Clostridial peptidoglycan [extracellular region] CC
Coagulation factor VIII precursor [platelet alpha granule lumen] UKENBCdOORHGURPPPPDDDD
COL1A2 [extracellular region] UKENBCdOOOOOOORHGUR
COL4A3(29-1670) [extracellular region] UKENBCdOOORRRRHHHHGURRRR
Collagen IV:vWF complex [extracellular region]
Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 [Homo sapiens]
Complement cascade [Homo sapiens]
Complement factor 3 [extracellular region]
Complement factor 4A [extracellular region]
Complement factor 5 [extracellular region]
Complex of CD19, CD81, CD225 and CD21 [plasma membrane]
Complex of CD19, CD81, CD225 and CD21 with C3d-bound Antigen [plasma membrane]
Conversion of C2 into C2a and C2b [Homo sapiens]
Conversion of C4 into C4a and C4b [Homo sapiens]
Creation of C4 and C2 activators [Homo sapiens]
Creation of the Membrane Attack Complex (MAC) [Homo sapiens]
CRTAM [plasma membrane] UKENBCdRHGUR
CRTAM binds to NECL2 [Homo sapiens]
CRTAM bound to NECL2 [plasma membrane]
CTLA-4 homodimer [plasma membrane]
CTLA4 [plasma membrane] UKENBCdOOOOORHGURPPPPDDDD
CXADR [plasma membrane] UKENBCdORHGURPPPPPPPPPDDDDDDDDD
CXADR binds to AMICA1 [Homo sapiens]
CXADR bound to JAML [plasma membrane]
CyP60 chaperones Basigin [Homo sapiens]
CyP60 complexed with Basigin [Golgi membrane]
DAG [plasma membrane] CC
DAPP1 [cytosol] UKEOGUPPDD
DARC [plasma membrane] UKENBCdORHGUR
DCC [plasma membrane] UKENBCdORHGUR
DDX58 [cytosol] UKENBCdORHGUR
Diacyl lipopeptide [extracellular region] C
Dimerization of phosphorylated IRF3/IRF7 [Homo sapiens]
Disinhibition of SNARE formation [Homo sapiens]
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:Mal:p-IRAK4 complex [Homo sapiens, Chlamydia trachomatis, etc.]
Dissociation of phosphorylated 4EBP1 from eIF4E [Homo sapiens]
dNQ-C3(672-1663) [extracellular region] UKENNBBCCddORHGURPPPPPPPPPDDDDDDDDD
Downstream signaling of activated FGFR [Homo sapiens]
DSCAM [plasma membrane] UKENBCdORHGUR
DSCAML1 [plasma membrane] UKENBCdRHGURPD
dsRNA binds to RIG-I [Homo sapiens]
dsRNA bound to RIG-I [cytosol]
E-cadherin bound to KLRG1 [plasma membrane]
E-cadherin bound to KLRG1 [plasma membrane]
EEA1 [endosome membrane] UKENBCdORHGURPPPDDD
EEA1:EEA1 [endosome membrane]
EEF2K [cytosol] UKKENBCdORHGUR
Effects of PIP2 hydrolysis [Homo sapiens]
eIF4E:4E-BP1-P [cytosol]
Elevation of cytosolic Ca2+ levels [Homo sapiens]
Engulfed CpG DNA binds to endosomal C-ter TLR9 [Homo sapiens]
Epithelial cadherin binds to KLRG1 [Homo sapiens]
Epithelial cadherin binds to KLRG1 in mice [Mus musculus]
Epithelial-cadherin precursor [plasma membrane] UENBCdRHRPPPPPPDDDDDD
ESAM [plasma membrane] UKENBCdRHGUR
F11R [plasma membrane] UKENBCdORRRHHHGURRPD
F2R [plasma membrane] UKENBCdORHGURPPPPPDDDDD
F2R(27-41) [extracellular region] UKENBCdORHGURPPPPPDDDDD
F2RL2 [plasma membrane] UKENBCdORHGUR
F2RL2(22-38) [extracellular region] UKENBCdORHGUR
F2RL3 [plasma membrane] UKENBCdORHGUR
F2RL3(18-47) [extracellular region] UKENBCdORHGUR
Factor B binds to C3(H2O) [Homo sapiens]
Factor B binds to surface-associated C3b [Homo sapiens]
Factor D cleaves C3(H2O)-bound Factor B [Homo sapiens]
Factor D cleaves C3b-bound Factor B [Homo sapiens]
Fc gamma receptors interact with antigen-bound IgG [Homo sapiens]
FCER1A [plasma membrane] UKENBCdORHGURPPPPPPPPPDDDDDDDDD
FCGR1A [plasma membrane] UKENBCdORHGUR
FCGR2A [plasma membrane] UKENBCdOGUPD
FCGR2B [plasma membrane] UKENBCdORRHHGURRPD
FCGR3A [plasma membrane] UKENNBBCCddORRHHGUR
FGF1 [extracellular region] UKENBCdORHGURPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
FGF10 [extracellular region] UKENBCdOORHGURPD
FGF16 [extracellular region] UKGU
FGF17-1 [extracellular region] UKENBCdORHGUR
FGF18 [extracellular region] UKENBCdORHGUR
FGF19 [extracellular region] UKENBCdORHGURPD
FGF2(10-155) [extracellular region] UKENBCdORHGURPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDD
FGF20 [extracellular region] UKENBCdORHGUR
FGF22 [extracellular region] UKENBCdORHGUR
FGF23 bound to Klotho and FGFR1c [plasma membrane]
FGF23(25-251) [extracellular region] UKENBCdOOORHGUR
FGF3 [extracellular region] UKENBCdOORHGUR
FGF4 [extracellular region] UKENBCdORHGURPD
FGF5-1 [extracellular region] UKENBCdORHGUR
FGF6 [extracellular region] UKENBCdORHGUR
FGF7 [extracellular region] UKENBCdORHGUR
FGF8-1 [extracellular region] UKENBCdORHGURPD
FGF9 [extracellular region] UKENBCdORHGURPPDD
FGFR ligand binding and activation [Homo sapiens]
FGFR1 ligand binding and activation [Homo sapiens]
FGFR1b [plasma membrane]
FGFR1b binds to FGF [Homo sapiens]
FGFR1b homodimer [plasma membrane]
FGFR1b homodimer bound to FGF [plasma membrane]
FGFR1b ligand binding and activation [Homo sapiens]
FGFR1b-binding FGFs [extracellular region]
FGFR1c [plasma membrane] UKENBCdOOOOOORHGURRPPPPPPPPPDDDDDDDDD
FGFR1c and Klotho ligand binding and activation [Homo sapiens]
FGFR1c binds to FGF [Homo sapiens]
FGFR1c binds to Klotho-bound FGF23 [Homo sapiens]
FGFR1c homodimer [plasma membrane]
FGFR1c homodimer bound to FGF [plasma membrane]
FGFR1c ligand binding and activation [Homo sapiens]
FGFR1c-binding FGFs [extracellular region]
FGFR2 ligand binding and activation [Homo sapiens]
FGFR2b binds to FGF [Homo sapiens]
FGFR2b ligand binding and activation [Homo sapiens]
FGFR2b long [plasma membrane] UKENBCdOOOOOOOOORHGURPPPPPPPPPPDDDDDDDDDD
FGFR2b long homodimer [plasma membrane]
FGFR2b long homodimer bound to FGF [plasma membrane]
FGFR2b-binding FGFs [extracellular region]
FGFR2c binds to FGF [Homo sapiens]
FGFR2c ligand binding and activation [Homo sapiens]
FGFR2c long [plasma membrane] UKENBCdOOOOOOOOORHGURPPPPPPPPPPDDDDDDDDDD
FGFR2c long homodimer [plasma membrane]
FGFR2c long homodimer bound to FGF [plasma membrane]
FGFR2c short [plasma membrane] UKENBCdOOOOOOOOORHGURPPPPPPPPPPDDDDDDDDDD
FGFR2c-binding FGFs [extracellular region]
FGFR3 ligand binding and activation [Homo sapiens]
FGFR3b [plasma membrane] UKENBCdOOOOOOOOOOOORHGURPD
FGFR3b binds to FGF [Homo sapiens]
FGFR3b homodimer [plasma membrane]
FGFR3b homodimer bound to FGF [plasma membrane]
FGFR3b ligand binding and activation [Homo sapiens]
FGFR3b-binding FGFs [extracellular region]
FGFR3c [plasma membrane] UKENBCdOOOOOOOOOOOORHGURPD
FGFR3c binds to FGF [Homo sapiens]
FGFR3c homodimer [plasma membrane]
FGFR3c homodimer bound to FGF [plasma membrane]
FGFR3c ligand binding and activation [Homo sapiens]
FGFR3c-binding FGFs [extracellular region]
FGFR4 [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 binds to FGF [Homo sapiens]
FGFR4 homodimer [plasma membrane]
FGFR4 homodimer bound to FGF [plasma membrane]
FGFR4 ligand binding and activation [Homo sapiens]
FGFR4-binding FGFs [extracellular region]
fibrin multimer [extracellular region]
fibrin multimer [plasma membrane]
Fibrinogen [extracellular region]
fibrinogen [platelet alpha granule lumen]
FIGF [extracellular region] UKENBCdORHGUR
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal [Homo sapiens, Chlamydia trachomatis, etc.]
FL-TLR7 dimer [endolysosome membrane]
fl-TLR9:unmethylated CpG DNA [endosome membrane]
Flagellin binds to TLR5 [Homo sapiens, Escherichia coli]
FN1(32-2386) [platelet alpha granule lumen] UKENBCdOGURPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDD
Formation of active mTORC1 complex [Homo sapiens]
Formation of alternative pathway C5 convertase [Homo sapiens]
Formation of C5b:C6 complex [Homo sapiens]
Formation of C5b:C6:C7 complex [Homo sapiens]
Formation of C5b:C6:C7:C8 complex [Homo sapiens]
Formation of classic pathway C5 convertase [Homo sapiens]
Formation of Classical C3 convertase (C4b:C2a complex) [Homo sapiens]
FRS2-mediated cascade [Homo sapiens]
FRS3 [plasma membrane] UKENBCdORHGUR
Fyn/Lyn-mediated phosphorylation of FcR1 gamma [Homo sapiens]
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) [Homo sapiens]
G-protein alpha (12):GDP [plasma membrane]
G-protein alpha (12):GTP [plasma membrane]
G-protein alpha (q/11): GTP [plasma membrane]
G-protein alpha (q/11):GDP [plasma membrane]
G-protein coupled receptor activity of Thrombin-activated PAR [plasma membrane]
G12/13 activation by PAR [Homo sapiens]
G13-activated p115-RhoGEF [plasma membrane]
GLYCAM1 [plasma membrane] UGU
GP VI : FceRI gamma dimer [plasma membrane]
GP VI : phosphorylated Fc Epsilon R1 gamma complex [plasma membrane]
GP6 [plasma membrane] UKGU
GPI-bound CD14 binds LPS [Homo sapiens]
GPIb [plasma membrane]
GPIb-IX-V binds to vWF:Collagen complex [Homo sapiens]
GPIb-IX-V complex [plasma membrane]
GPIN-CD14(20-345) [plasma membrane] UKENBCdORRHHGURR
GPVI-mediated activation cascade [Homo sapiens]
Gq activation by PAR [Homo sapiens]
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
GRB2:GAB1:PI3Kreg binds to p-SHP2 on p-FRS2:activated FGFR [Homo sapiens]
GTP loading by Rheb [Homo sapiens]
Guanine nucleotide-binding protein beta subunit [plasma membrane]
Guanine nucleotide-binding protein gamma subunit [plasma membrane]
guanyl-nucleotide exchange factor activity of G13-activated p115-RhoGEF [plasma membrane]
HCST [plasma membrane] UKENBCdRRHHGURR
Hemostasis [Homo sapiens]
Hepatocyte growth factor [extracellular region]
Hepatocyte growth factor [platelet alpha granule lumen]
Heterdimerization of CEACAMs [Homo sapiens]
Heterotrimeric G-protein G12 (active) [plasma membrane]
Heterotrimeric G-protein G12 (inactive) [plasma membrane]
Heterotrimeric G-protein Gq (active) [plasma membrane]
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane]
HGF(32-494) [platelet alpha granule lumen] UKENBCdORRRHHHGURRRPPPPPPPPDDDDDDDD
HGF(495-728) [extracellular region] UKENBCdORRRHHHGURRRPPPPPPPPDDDDDDDD
HGF(495-728) [platelet alpha granule lumen] UKENBCdORRRHHHGURRRPPPPPPPPDDDDDDDD
HLA Bw4 interacting with KIR3DL1 [plasma membrane]
HLA class I histocompatibility antigen, A-1 alpha chain precursor [plasma membrane] UKEOGUPPDD
HLA class I histocompatibility antigen, A-2 alpha chain [plasma membrane] UKEENNBBCCddORRHHGURRPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
HLA class I histocompatibility antigen, A-3 alpha chain precursor [plasma membrane] UKENBCdORHGURPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD
HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] UKENBCdOGUR
HLA class I histocompatibility antigen, alpha chain G precursor [plasma membrane] UKEEENBCdORHGURPPPDDD
HLA class I histocompatibility antigen, Cw-3 alpha chain precursor [plasma membrane] UEOOGUPPPDDD
HLA class I histocompatibility antigen, Cw-4 alpha chain precursor [plasma membrane] UEOOGUPPPDDD
HLA class I histocompatibility antigen, Cw-5 alpha chain precursor [plasma membrane] UEOOGUPPPDDD
HLA class I histocompatibility antigen, Cw-6 alpha chain precursor [plasma membrane] UEOOGUPPPDDD
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [plasma membrane] UKENBCdORHGUR
HLA class I histocompatibility antigen, E alpha chain precursor [plasma membrane] UKEEOGUPPPPDDDD
HLA class II histocompatibility antigen, DP [plasma membrane] UKENBCdRHGUR
HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] UKEEENBCdORHGURPD
HLA class II histocompatibility antigen, DQ [plasma membrane] UKEENBCdRHGUR
HLA class II histocompatibility antigen, DQ [plasma membrane] UKEEGUPPPDDD
HLA class II histocompatibility antigen, DQ [plasma membrane] UKKEENNBBCCddOGUPPPDDD
HLA class II histocompatibility antigen, DQ beta 2 chain [plasma membrane] UKEGU
HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor [plasma membrane] UKEEGUPPPDDD
HLA class II histocompatibility antigen, DR alpha chain precursor [plasma membrane] UKEOGUPPPPPPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DR-1 beta chain precursor [plasma membrane] UKEENBCdOOGUPD
HLA class II histocompatibility antigen, DRB1-15 beta chain [plasma membrane] UKENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-9 beta chain precursor [plasma membrane] UENNBBCCddORHGURPPPPDDDD
HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [plasma membrane] UKENBCdOORHGUR
HLA-A3 [plasma membrane]
HLA-A3 interacting with KIR3DL2 [plasma membrane]
HLA-Bw4 [plasma membrane]
HLA-C Cw3 (group 1) [plasma membrane]
HLA-C Cw4 (group 2) [plasma membrane]
HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane]
HLA-C group 1 interacting with KIR2DS2 [plasma membrane]
HLA-C group 2 interacting with KIR2DL1 [plasma membrane]
HLA-C group 2 interacting with KIR2DS1 [plasma membrane]
HLA-C group-I-interacting KIRs [plasma membrane]
HLA-E [plasma membrane]
HLA-E interacting with KLRC1:KLRD1 [plasma membrane]
HLA-G [plasma membrane]
HLA-G interacting with KIR2DL4 [plasma membrane]
Hormone Sensitve Lipase [cytosol] UENBCdRHR
HRG [extracellular region] UKENBCdORHGUR
HS [extracellular region] CC
Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B [Homo sapiens]
I(1,4,5)P3 [cytosol] CCP
I(1,4,5)P3 [platelet dense tubular network membrane] CCP
ICAM 1-4 [plasma membrane]
ICAM1 [plasma membrane] UKENBCdORHGURPPPPPPPPDDDDDDDD
ICAM1-4 bind Integrin alphaLbeta2 (LFA-1) [Homo sapiens]
ICAM2 [plasma membrane] UKENBCdORRRRRHHHHHGURRRRRPD
ICAM3 [plasma membrane] UKENBCdORHGURPD
ICOS-1 [plasma membrane] UKENBCdOORHGUR
ICOSLG [plasma membrane] UKKENBCdORHGUR
IFITM1 [plasma membrane] UKENBCdORHGUR
Ig Antibody Light Chain [extracellular region]
Ig Heavy Chain V Region [extracellular region]
Ig Kappa Light Chain V Region [extracellular region]
Ig Lamda Light Chain V Region [extracellular region]
IGF1 [platelet alpha granule lumen] UKEOOGUPPPPPDDDDD
IgG [extracellular region]
IgH heavy chain V-III region VH26 precursor [extracellular region] UEGUPD
IGHV(1-?) [extracellular region] UGU
IGHV7-81(1-?) [extracellular region] UEGU
IGKC [extracellular region] UEOGUPPPPPDDDDD
IGKV1-5(23-?) [extracellular region] UEGU
IGKV4-1(21-?) [extracellular region] UEGU
IGKVA18(21-?) [extracellular region] UEGU
IGLC1 [extracellular region] UGU
IGLV(23-?) [extracellular region] UEGU
IGLV1-36(1-?) [extracellular region] UEGU
IGLV1-40(1-?) [extracellular region] UEGU
IGLV1-44(1-?) [extracellular region] UEGU
IGLV10-54(1-?) [extracellular region] UEGU
IGLV11-55(1-?) [extracellular region] UENBCdGU
IGLV2-11(1-?) [extracellular region] UEGU
IGLV2-18(1-?) [extracellular region] UEGU
IGLV2-23(1-?) [extracellular region] UEGU
IGLV2-33(1-?) [extracellular region] UEGU
IGLV3-12(1-?) [extracellular region] UEGU
IGLV3-16(1-?) [extracellular region] UEGU
IGLV3-22(1-?) [extracellular region] UEGU
IGLV3-25(1-?) [extracellular region] UEGU
IGLV3-27(1-?) [extracellular region] UEGU
IGLV4-3(1-?) [extracellular region] UEGU
IGLV4-60(1-?) [extracellular region] UEGU
IGLV4-69(1-?) [extracellular region] UEGU
IGLV5-37(1-?) [extracellular region] UEGU
IGLV5-45(1-?) [extracellular region] UENBCdGU
IGLV7-43(1-?) [extracellular region] UEGU
IGLV7-46(1-?) [extracellular region] UEGU
IGLV8-61(1-?) [extracellular region] UEGU
IL1R1 [plasma membrane] UKENBCdORHGURPPPDDD
IL1R2 [plasma membrane] UKENBCdORRHHGURR
IL2RB [plasma membrane] UKENBCdORHGURPPPPDDDD
IL6R [plasma membrane] UKENBCdORHGURPPPDDD
Imidazoquinoline compounds [endosome membrane]
IMIQ [endosome membrane] C
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell [Homo sapiens]
Inhibition of HSL [Homo sapiens]
Inhibition of TSC complex formation by PKB [Homo sapiens]
Initial triggering of complement [Homo sapiens]
INPP5D [cytosol] UKGU
Integrin alpha IIb beta 3:Fibrin complex [plasma membrane]
Integrin alpha2bbeta3 [plasma membrane]
Integrin alpha2beta1 [plasma membrane]
Integrin alpha3beta1 [plasma membrane]
Integrin alpha3beta1, alpha6beta1 [plasma membrane]
Integrin alpha4beta1 (VLA-4) [plasma membrane]
Integrin alpha4beta1 binds JAM2 [Homo sapiens]
integrin alpha4beta1:JAM2 [plasma membrane]
integrin alpha4beta1:VCAM1 [plasma membrane]
Integrin alpha4beta7 [plasma membrane]
Integrin alpha4beta7:MADCAM1 [plasma membrane]
Integrin alpha5beta1 [plasma membrane]
Integrin alpha5beta1 binds FN1 dimer [Homo sapiens]
Integrin alpha5beta1:FN1 dimer [plasma membrane]
Integrin alpha6beta1 [plasma membrane]
Integrin alphaLbeta2 (LFA-1) [plasma membrane]
Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) [Homo sapiens]
Integrin alphaLbeta2:F11R [plasma membrane]
Integrin alphaMbeta2 (MAC1) binds JAM3 [Homo sapiens]
Integrin alphaMbeta2 [plasma membrane]
Integrin alphaMbeta2:JAM3 [plasma membrane]
Integrin alphaXbeta2 [plasma membrane]
Integrin alphaXbeta2 binds JAM3 [Homo sapiens]
Integrin alphaXbeta2:JAM3 [plasma membrane]
Integrins alpha1beta1, alpha2beta1:Collagen type I fibril:Mg2+ [plasma membrane]
IP3 receptor bound to IP3 and Ca++ [platelet dense tubular network membrane]
IPS-1 interacts with RIP-1 and FADD [Homo sapiens]
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:Mal complex [Homo sapiens, Chlamydia trachomatis, etc.]
IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:Mal:activated TLR [plasma membrane]
IRAK3 [cytosol] UKENBCdORHGUR
IRAK4 [cytosol] UKENBCdOOORHGUR
IRAK4 binds to the activated TLR receptor:Mal:MyD88 complex [Homo sapiens, Chlamydia trachomatis, etc.]
IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
IRF3 [cytosol] UKENBCdORHGURPPPPDDDD
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR [Homo sapiens]
ITGA2B(32-?) [platelet alpha granule membrane] UKENBCdOORHGURPPPPPPPPPPPPPPDDDDDDDDDDDDDD
ITGA3(33-1051) [plasma membrane] UKENBCdORHGUR
ITGA4 [plasma membrane] UKEOGU
ITGA5(42-894) [plasma membrane] UKENBCdORHGUR
ITGA6(24-1130) [plasma membrane] UKEOOGU
ITGAL [plasma membrane] UKENBCdORHGURPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDD
ITGAM [plasma membrane] UKENBCdORHGURPPPPPPPPPPDDDDDDDDDD
ITGAX [plasma membrane] UKENBCdORHGURPD
ITGB2 [plasma membrane] UKENBCdOORHGURPPPDDD
ITGB3(27-?) [platelet alpha granule membrane] UKENBCdOORHGURPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDD
JAM-A Homodimer [plasma membrane]
JAM-A homodimerises [Homo sapiens]
JAM-B binds JAM-C [Homo sapiens]
JAM-B bound to JAM-C [plasma membrane]
JAM-B homodimer [plasma membrane]
JAM-B homodimerises [Homo sapiens]
JAM-C homodimer [plasma membrane]
JAM-C homodimerises [Homo sapiens]
JAM2 [plasma membrane] UKENBCdORHGUR
JAM2(20-394) [plasma membrane] UKENBCdORHGUR
JAM3 [plasma membrane] UKENBCdORHGUR
K63-linked ubiquitination of RIP1 bound to the activated TLR complex [Homo sapiens]
kinase activity of Activated mTORC1 [cytosol]
kinase activity of Activated PI3K [plasma membrane]
kinase activity of Phosphorylated AKT-1 [cytosol]
kinase activity of PIP3:PDK1 complex [plasma membrane] [plasma membrane]
kinase activity of PIP3:Phosphorylated PKB complex [plasma membrane]
kinase activity of S6K1-P [cytosol]
KIR2DL1 [plasma membrane] UKENBCdOOORRHHGURPPDD
KIR2DL1 interacting with HLA-C group 2 (Cw3) [Homo sapiens]
KIR2DL2 [plasma membrane] UK