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name	phosphoribosylformylglycinamidine synthase activity
Accession	GO
Definition	Catalysis of the reaction: ATP + 5'-phosphoribosylformylglycinamide + L-glutamine + H2O = ADP + phosphate + 5'-phosphoribosylformylglycinamidine + L-glutamate.
Enzyme Classification (EC) number	6.3.5.3 6.3.5.3
Molecules/complexes with this activity
ENSCAFP00000025062 [cytosol] EE ENSRNOP00000007087 [cytosol] EE ENSTGUP00000016583 [cytosol] EE FGAM synthase [cytosol] UEGBCdORHUR Homologues of FGAM synthase [cytosol] Homologues of FGAM synthase [intracellular] Homologues of FGAM synthase [intracellular] O14228 [cytosol] UKEG P15254 [intracellular] UKKE P35421 [cytosol] UKEEGBCdFRRR ... List all 17 items
Reactions catalysed by this activity
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Homo sapiens] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Canis familiaris] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Bos taurus] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Mus musculus] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Rattus norvegicus] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Taeniopygia guttata] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Danio rerio] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Drosophila melanogaster] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Caenorhabditis elegans] FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi [Arabidopsis thaliana] ... List all 17 items
Is a specialisation of activities
carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO ligase activity, forming carbon-nitrogen bonds GO ligase activity GO catalytic activity GO molecular_function GO