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name	cyclin-dependent protein kinase activity
Accession	GO
Definition	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
Enzyme Classification (EC) number	2.7.11.22 2.7.11.22
Molecules/complexes with this activity
active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] active nuclear Cyclin B1:Cdc2 complexes [nucleoplasm] ... List all 87 items
Reactions catalysed by this activity
CDK5 phosphorylates DARPP-32 on Thr75 [Homo sapiens] CDK5 phosphorylates DARPP-32 on Thr75 [Canis familiaris] CDK5 phosphorylates DARPP-32 on Thr75 [Bos taurus] CDK5 phosphorylates DARPP-32 on Thr75 [Mus musculus] CDK5 phosphorylates DARPP-32 on Thr75 [Rattus norvegicus] CDK5 phosphorylates DARPP-32 on Thr75 [Danio rerio] Cyclin A:Cdk2 mediated phosphorylation of p27/p21 [Homo sapiens] Cyclin A:Cdk2 mediated phosphorylation of p27/p21 [Canis familiaris] Cyclin A:Cdk2 mediated phosphorylation of p27/p21 [Bos taurus] Cyclin A:Cdk2 mediated phosphorylation of p27/p21 [Sus scrofa] ... List all 110 items
Is a specialisation of activities
protein serine/threonine kinase activity GO protein kinase activity GO kinase activity GO transferase activity, transferring phosphorus-containing groups GO transferase activity GO catalytic activity GO molecular_function GO phosphotransferase activity, alcohol group as acceptor GO transferase activity, transferring phosphorus-containing groups GO transferase activity GO catalytic activity GO molecular_function GO