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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
First nameSanford J
AffiliationUniversity of California, San Diego, Department of Medicine
Kasirer-Friede, A, Moran, B, Nagrampa-Orje, J, Swanson, K, Ruggeri, ZM, Schraven, B, Neel, BG, Koretzky, G, Shattil, SJ ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists 2007 Blood PubMed
Obergfell, A, Eto, K, Mocsai, A, Buensuceso, C, Moores, SL, Brugge, JS, Lowell, CA, Shattil, SJ Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton 2002 J Cell Biol PubMed
Judd, BA, Myung, PS, Obergfell, A, Myers, EE, Cheng, AM, Watson, SP, Pear, WS, Allman, D, Shattil, SJ, Koretzky, GA Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling 2002 J Exp Med PubMed
Judd, BA, Myung, PS, Leng, L, Obergfell, A, Pear, WS, Shattil, SJ, Koretzky, GA Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors 2000 Proc Natl Acad Sci U S A PubMed
Calderwood, DA, Shattil, SJ, Ginsberg, MH Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling 2000 J Biol Chem PubMed
Shattil, SJ Integrins and Src: dynamic duo of adhesion signaling 2005 Trends Cell Biol PubMed
Shattil, SJ, Newman, PJ Integrins: dynamic scaffolds for adhesion and signaling in platelets 2004 Blood PubMed
Kasirer-Friede, A, Kahn, ML, Shattil, SJ Platelet integrins and immunoreceptors 2007 Immunol Rev PubMed
Arias-Salgado, EG, Haj, F, Dubois, C, Moran, B, Kasirer-Friede, A, Furie, BC, Furie, B, Neel, BG, Shattil, SJ PTP-1B is an essential positive regulator of platelet integrin signaling 2005 J Cell Biol PubMed
Gao, J, Zoller, KE, Ginsberg, MH, Brugge, JS, Shattil, SJ Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3 1997 EMBO J PubMed
Clark, EA, Shattil, SJ, Ginsberg, MH, Bolen, J, Brugge, JS Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3 1994 J Biol Chem PubMed
Kasirer-Friede, A, Cozzi, MR, Mazzucato, M, De Marco, L, Ruggeri, ZM, Shattil, SJ Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors 2004 Blood PubMed
Shattil, SJ Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways 1999 Thromb Haemost PubMed
Obergfell, A, Judd, BA, del Pozo, MA, Schwartz, MA, Koretzky, GA, Shattil, SJ The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton 2001 J Biol Chem PubMed
Woodside, DG, Obergfell, A, Talapatra, A, Calderwood, DA, Shattil, SJ, Ginsberg, MH The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin beta cytoplasmic domains 2002 J Biol Chem PubMed