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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:Q9NWZ3
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Interleukin-1 receptor-associated kinase 4 shortName:IRAK-4 ecNumber2.7.11.1/ecNumber alternativeName: Renal carcinoma antigen NY-REN-64
Links to corresponding entries in other databasesBioGPS Gene:51135
Brenda:2.7.11.1
CTD Gene:51135
EC:2.7.11.1
ENSEMBL:ENSG00000198001
GeneCards:Q9NWZ3
HapMap:NM_016123
IntEnz:2.7.11.1
KEGG Gene:51135
NCBI Gene:51135
OMIM:606883
OMIM:607676
OMIM:610799
RefSeq:NM_016123
RefSeq:NP_057207
UCSC human:Q9NWZ3
UniProt:Q9NWZ3
dbSNP Gene:51135
Other identifiers related to this sequenceIRAK4_HUMAN, Q69FE1, Q8TDF7, Q9Y589, ENSG00000198001, ENST00000356669, ENSP00000349096, 219618_at, 81368_at, g7705840_3p_x_at, 219618_3p_at, A_14_P122539, A_23_P13978, A_24_P158903, CCDS8744, GE58687, GE801884, GE825166, AK027301, AY283670, AY340964, AY340965, AY340966, AY340967, AY340962, AY340963, AY730682, AF445802, AF155118, AK000528, AY186092, BC013316, AY283671, EntrezGene:51135, GI_7705840-S, ILMN_5035, IPI00007641, IPI00798404, IPI00385374, MIM:606883, MIM:607676, MIM:610799, BAD12234, AAP57089, AAR02360, AAR02361, AAR02362, AAR02363, AAR02358, AAR02359, AAX22228, AAM15772, AAD42884, BAA91232, AAN75440, AAH13316, AAP57090, NM_016123, NP_057207, Hs.138499, Q6ZWT8, Q7Z6A8, Q69FE1, Q69FE3, Q9NWZ3, Q7Z6A7, Q6ZWT8_HUMAN, Q7Z6A8_HUMAN, Q69FE1_HUMAN, Q69FE3_HUMAN, IRAK4_HUMAN, Q7Z6A7_HUMAN, IPR001245, IPR000719
Molecules with this sequenceIRAK4 [cytosol] UKENBCdOOORHGUR
p-T342,T345,S346-IRAK4 [cytosol] UKENBCdOOORHGUR
p-T342,T345,S346-IRAK4 [plasma membrane] UKENBCdOOORHGUR
IRAK4 [plasma membrane] UKENBCdOOORHGUR
p-T342,T345,S346-IRAK4 [endosome membrane] UKENBCdOOORHGUR
IRAK4 [endosome membrane] UKENBCdOOORHGUR
Component ofIL1 receptor complex [plasma membrane]
IRAK4: p-Pellino-1,2,3 [cytosol]
IRAK4: Pellino-1,2,3 [cytosol]
IL1 receptor complex - activated IRAK4:TOLLIP [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR receptor [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
...
List all 45 items
Represented by generalisation(s)hp-IRAK1, IRAK4 [cytosol]
Processes where molecules and complexes with this sequence are involved

Immune System

Modifications in molecules with this sequenceO-phospho-L-threonine at 342
O-phospho-L-threonine at 345
O-phospho-L-serine at 346
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