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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:Q9NWZ3
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Interleukin-1 receptor-associated kinase 4 shortName:IRAK-4 ecNumber2.7.11.1/ecNumber alternativeName: Renal carcinoma antigen NY-REN-64
Links to corresponding entries in other databasesBioGPS Gene:51135
Brenda:2.7.11.1
CTD Gene:51135
EC:2.7.11.1
ENSEMBL:ENSG00000198001
GeneCards:Q9NWZ3
HapMap:NM_016123
IntEnz:2.7.11.1
KEGG Gene:51135
NCBI Gene:51135
OMIM:606883
OMIM:607676
OMIM:610799
Orphanet:16266
PRO:Q9NWZ3
RefSeq:NM_016123
RefSeq:NP_057207
UCSC human:Q9NWZ3
UniProt:Q9NWZ3
ZINC_target:Q9NWZ3
dbSNP Gene:51135
Other identifiers related to this sequenceIRAK4_HUMAN, Q69FE1, Q8TDF7, Q9Y589, XP_005269004, 2O8Y, IPR017428, 3412321, ENSG00000198001, PF07714, LRG_75, HGNC:17967, SM00219, SM00220, 3412307, AAR02362, 3412324, 10508479, 3772297, 3412322, AK299944, XP_005269005, IPR001245, 51135, XP_006719505, AAN75440, MIM:610799, 7954969, AC093012, IRAK4-005, Hs.138499, AAR02361, OTTHUMP00000241037, AY186092, AAD42884, BC013316, 2NRU, 3412318, 11740649_a_at, IPR000719, 11742042_a_at, uc010sky.1, MIM:606883, 2NRY, BAG61774, AY340966, 3412320, AY340964, 3412297, AY340967, 2OIC, IPR002290, CCDS44862, AF155118, IPR011009, AAR02363, HPA000924, ENSP00000408734, XP_006719502, NP_001138730, CAB016685, NM_001145258, MIM:607676, 3412309, 3412311, XP_006719503, AAH13316, AK000528, AY340965, 81368_at, 16750277, CAB022077, IRAK4, 2OID, PF00069, 3412308, UPI0000401AEB, EntrezGene:51135, 3412317, 3412316, 2OIB, 3412323, XP_006719504, AAM15772, AF445802, BAA91232, XP_006719506, 3412325, PR00109, 3MOP, IPR020635, AAR02360, g7705840_3p_x_at, XM_005268944, AAX22228, XM_005268946, A_23_P13978, 3412302, 11734066_x_at, AY340962, A_24_P158903, ILMN_1692352, AY730682, 3412326, XP_005269003, OTTHUMP00000241041, uc001rnt.3, LRG_75t1, ENST00000448290, 11734067_a_at, F8VW24, 219618_3p_at, XP_005269001, GE58687, F8VR40, EAW57867, 3412306, XP_006719501, NP_057207, ENST00000551736, AY340963, 0002370333, Q69FE3, ENSP00000390651, XM_005268943, 3412327, IPR011029, AAR02358, UPI000004ABE6, XP_005269000, XP_005269002, NM_016123, 3412328, 219618_at, AAR02359, IRAK4-001, ENSP00000446490, CH471111, CCDS8744, uc001rnu.3, NP_001107654, NM_001114182, IRAK4-002, 3412299, OTTHUMP00000241042, GE595587, IRAK4-201, ENSP00000390327, XM_005268949, NM_001145256, 3412329, 3412330, uc001rny.3, NP_001138729, NP_001138728, NM_001145257, XP_005269006
Molecules with this sequenceIRAK4 [cytosol] UKENBCdOOOORHPGURZ
p-T342,T345,S346-IRAK4 [cytosol] UKENBCdOOOORHPGURZ
p-T342,T345,S346-IRAK4 [plasma membrane] UKENBCdOOOORHPGURZ
IRAK4 [plasma membrane] UKENBCdOOOORHPGURZ
p-T342,T345,S346-IRAK4 [endosome membrane] UKENBCdOOOORHPGURZ
IRAK4 [endosome membrane] UKENBCdOOOORHPGURZ
Component ofIL1 receptor complex [plasma membrane]
IRAK4: p-Pellino-1,2,3 [cytosol]
IRAK4: Pellino-1,2,3 [cytosol]
IL1 receptor complex - activated IRAK4:TOLLIP [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:Mal:activated TLR receptor [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
IRAK4:oligo-MyD88:Mal:activated TLR [plasma membrane]
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
p-S,2T-IRAK4:oligo-MyD88:activated TLR7/8 or 9 receptor [endosome membrane]
IRAK4:oligo-MyD88:activated TLR 7/8 or 9 [endosome membrane]
...
List all 45 items
Represented by generalisation(s)hp-IRAK1, IRAK4 [cytosol]
Processes where molecules and complexes with this sequence are involved

Immune System

Modifications in molecules with this sequenceO-phospho-L-threonine at 342
O-phospho-L-threonine at 345
O-phospho-L-serine at 346
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