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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
SurnameJoshi-Tope
First nameGeeta
InitialsG
AffiliationCold Spring Harbor Laboratory
Author of summation(s)
After assembly of the complete RNA polymerase II-preinitiati...
After transcription, some RNA molecules are altered to conta...
Although TBP (TATA box binding factor) is necessary and suff...
Aly/Ref recruits TAP to the Exon Junction Complex. This make...
Apoptosis is a distinct form of cell death that is functiona...
Binding of XPC complex to the damaged site on the DNA substr...
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Cross-linking experiments performed in the yeast system have...
Cytosolic fatty acid synthase (FAS) complex catalyzes the re...
DNA damage can be directly reversed by dealkylation.
DNA repair is a phenomenal multi-enzyme, multi-pathway syste...
Dual incision at defined positions flanking the DNA damage i...
Factor TFIIE enters the preinitiation complex after TFIIF re...
Formation of phosphodiester bonds nine and ten creates RNA ...
Formation of the open complex exposes the template strand t...
Formation of the pre-initiation complex...
Formation of the second phosphodiester bond creates a 3-nt p...
Formation of the second phosphodiester bond creates a 3-nt p...
Formation of the third phosphodiester bond creates a 4-nt p...
Gap junctions are clusters of intercellular channels connect...
Gene Expression covers the pathways by which genomic DNA is ...
Histone mRNAs are exported by a mechanism that requires TAP,...
Histone mRNAs are exported by a mechanism that requires TAP,...
In a healthy, well-nourished individual, the production of k...
In humans the deamination of adenosines to inosines is the m...
NER was first described in the model organism E. coli in the...
Numerous types of DNA damage can occur within a cell due to ...
Of the three major pathways involved in the repair of nucleo...
Post-transcriptional splicing of introns is affected neither...
Processing is initiated once the SLBP (bound to the stem loo...
Processing is initiated once the U7 snRNP is loaded onto the...
Protein synthesis is accomplished through the process of tra...
Proteolytic and scanning electron microscopy studies indicat...
Proteolytic and scanning electron microscopy studies indicat...
Reactive cellular catabolites can cause DNA damage by 6-O-me...
RNA Polymerase II promoter escape occurs after the first pho...
RNA polymerase II transcription complexes are susceptible to...
RNA polymerase III is one of three types of nuclear RNA poly...
Several subunits of the NER multiprotein repair machinery ar...
SNAPc binds specifically to the PSE. This binding is mediat...
Telomeres are protein-DNA complexes at the ends of linear ch...
TFIIIA contains nine C2H2 zinc fingers (Arakawa et al., 1995...
The 32 kDa stem-loop binding protein (SLBP), also termed hai...
The binding of SNAPc to the PSE is stabilized not only by co...
The binding of TFIIH completes the assembly of the preinitia...
The cleavage of the damaged strand of DNA 3' to the site of ...
The cleavage of the damaged strand of DNA 5' to the site of ...
The detailed annotation of this section will be completed in...
The general transcription factor TFIIB is a single polypepti...
The general transcription factor TFIIF has a high affinity f...
The HRR pathway is an "error free" DNA repair mechanism that...
The levels of acetone in ketone bodies are much lower than t...
The mechanisms governing the process of elongation during eu...
The metazoan-specific type 3 promoters, which are exemplifie...
The NHEJ pathway is initiated in response to the formation o...
The preferential repair of UV-induced damage in transcribed ...
The recruitment of Brf1-TFIIIB to type 1 and 2 promoters has...
The replication of the genome and the subsequent segregation...
The snRNA activating protein complex (SNAPc) (Sadowski et al...
The type 1 promoters recruit TFIIIA, the founding member of ...
The type 2 promoters can recruit TFIIIC without the help of ...
The U1 snRNP is a particle consisting of the U1 snRNA and Sm...
The U4atac/U6atac enters the spliceosome and U6atac snRNA fo...
The U7 snRNP. This particle contains the U7 snRNA, the smal...
There are three basic types of RNA polymerase III promoters....
There are two well-documented trans-acting factors required ...
This class of mRNAs is expressed from genes that lack intron...
This section includes the cleavage of both polyadenylated an...
Transcription by RNA Polymerase I, RNA Polymerase III and t...
Transcription factor II H (TFIIH) and XPG are added to the d...
Transport of mRNA through the Nuclear Pore Complex (NPC) is ...
Two DNA helicases XPG and XPD, which are part of TFIIH, unwi...
U12-type AT-AC introns are distinguished from the major U2-t...
Author of entries
/figures/atac_1.jpg
/figures/atac_2.jpg
/figures/atac_3.jpg
/figures/atac_4.jpg
/figures/atac_5.jpg
/figures/atac_6.jpg
/figures/cyclinab_cdk1.jpg
/figures/cyclinab_cdk1_dp.jpg
/figures/cyclinab_cdk1_g2m.jpg
/figures/cyclinab_cdk1_p.jpg
/figures/cycline_cdk2.jpg
/figures/cycline_cdk2_dp.jpg
/figures/cycline_cdk2_g1s.jpg
/figures/cycline_cdk2_p.jpg
/figures/cytoC_mediated_response.jpg
/figures/denovo_IMP_synthesis.jpg
/figures/fructose_catab.jpg
/figures/g2m.jpg
/figures/galactose_catab.jpg
/figures/glucose_uptake.jpg
/figures/glycolysis_gluconeogenesis.png
/figures/ox_decarb_and_TCA.jpg
/figures/purine_catabolism.jpg
/figures/purine_salvage.jpg
/figures/pyrimidine_catabolism.jpg
/figures/pyrimidine_salvage.jpg
/figures/SMAC_mediated_response.jpg
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing [Homo sapiens]
3' incision of the lesioned strand of DNA in TC-NER [Homo sapiens]
3'- incision of DNA by XPG in GG-NER [Homo sapiens]
3'-polyadenylated, capped mRNA complex [nucleoplasm]
5' incision leading to excision of DNA fragment with lesion in TC-NER [Homo sapiens]
5'-incision of DNA by ERCC1-XPF in GG-NER [Homo sapiens]
53BP1 associates with gamma H2AX at nuclear foci [Homo sapiens]
6-O-methyguanine containing damaged DNA [nucleoplasm]
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest [Homo sapiens]
A to I edited RNA [nucleoplasm]
A to I edited RNA:Editosome (ADAR1) complex [nucleoplasm]
ABH2 mediated Reversal of Alkylation Damage [Homo sapiens]
ABH3 mediated Reversal of Alkylation Damage [Homo sapiens]
Abortive initiation after formation of the first phosphodiester bond [Homo sapiens]
Abortive Initiation After Second Transition [Homo sapiens]
Abortive Initiation Before Second Transition [Homo sapiens]
Abortive termination of early transcription elongation by DSIF:NELF [Homo sapiens]
Abortive termination of elongation after arrest [Homo sapiens]
Activated BAX [mitochondrial outer membrane]
Activation of caspases through apoptosome-mediated cleavage [Homo sapiens]
Active oligomeric BAK [mitochondrial outer membrane]
Active Pol II complex with repaired DNA template:mRNA hybrid [nucleoplasm]
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition [Homo sapiens]
Addition of Nucleotides 5 through 9 on the growing Transcript [Homo sapiens]
Addition of nucleotides between position +11 and +30 [Homo sapiens]
Addition of nucleotides leads to transcript elongation [Homo sapiens]
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition [Homo sapiens]
Addition of the third nucleotide on the nascent transcript [Homo sapiens]
ALYREF [nucleoplasm] UKENBCdORHPGUR
Apaf-1:Cytochrome C [cytosol]
Apoptosis [Homo sapiens]
Apoptosis induced DNA fragmentation [Homo sapiens]
Apoptosome [cytosol]
Apoptotic cleavage of cellular proteins [Homo sapiens]
Apoptotic factor-mediated response [Homo sapiens]
Assembly of repair proteins at the site of Pol II blockage [Homo sapiens]
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks [Homo sapiens]
Assembly of the RAD51-ssDNA nucleoprotein complex [Homo sapiens]
Association of RPA complexes with ssDNA [Homo sapiens]
Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex [Homo sapiens]
Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks [Homo sapiens]
Association of gamma-H2AX with NBS1 [Homo sapiens]
Association of Ku heterodimer with ends of DNA double-strand break [Homo sapiens]
Association of MRN with sites of DSB [Homo sapiens]
Association of RAD50:MRE11 complex with NBS1 via MRE11 interaction [Homo sapiens]
Association of RAD51 with BRCA2 [Homo sapiens]
Association of RAD51 with RAD52:DNA double-strand break ends [Homo sapiens]
Association of RAD51 with the RPA complex [Homo sapiens]
Association of RAD52 with the RPA complex [Homo sapiens]
ATAC A Complex [nucleoplasm]
ATAC B Complex [nucleoplasm]
ATAC C Complex [nucleoplasm]
ATAC C Complex with lariat containing 5'-end cleaved mRNA [nucleoplasm]
ATAC spliceosome mediated 3' splice site cleavage, exon ligation [Homo sapiens]
ATAC spliceosome mediated Lariat formation,5' splice site cleavage [Homo sapiens]
ATM mediated phosphorylation of repair proteins [Homo sapiens]
ATM mediated response to DNA double-strand break [Homo sapiens]
Autophosphorylation of DNA-PKcs [Homo sapiens]
BAD:BCL-2 [mitochondrial outer membrane]
BCL2L1 [mitochondrial outer membrane] UKENBCdORHPGPPPPPPPPPPPPPPPURDDDDDDDDDDDDDDDZ
Binding of A1CF to stem-looped RNA [Homo sapiens]
Binding of ADAR1 homodimer to dsRNA duplex [Homo sapiens]
Binding of ADAR2 homodimer to dsRNA duplex [Homo sapiens]
Binding of APOBEC-1 to form editosome [Homo sapiens]
Binding of ERCC1-XPF to preincision complex [Homo sapiens]
Binding of SLBP to Replication-Dependent Histone Pre-mRNA [Homo sapiens]
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex [Homo sapiens]
Binding of TFIIE to the growing preinitiation complex [Homo sapiens]
Binding of TFIIIA To type 1 Promoter [Homo sapiens]
Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex [Homo sapiens]
Binding of TFIIIC to TFIIIA:Type I Promoter complex [Homo sapiens]
BRCA1 associates with 53BP1at the site of DNA double-strand break [Homo sapiens]
Budding and maturation of HIV virion [Homo sapiens]
C to U edited ApoB RNA [nucleoplasm]
C4 deamination of cytidine [Homo sapiens]
C6 deamination of adenosine [Homo sapiens]
Capped intronless pre-mRNA [nucleoplasm]
capped intronless pre-mRNA:CBC complex [nucleoplasm]
capped, methylated pre-mRNA [nucleoplasm]
Cell Cycle, Mitotic [Homo sapiens]
Chromosome Maintenance [Homo sapiens]
Cleavage of Growing Transcript in the Termination Region [Homo sapiens]
Cleavage of Holliday junctions [Homo sapiens]
Cleavage of Procaspase-3 by the apoptosome [Homo sapiens]
Cleavage of Procaspase-7 by the apoptosome [Homo sapiens]
Cleavage of Procaspase-9 to Caspase-9 [Homo sapiens]
Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA [Homo sapiens]
Cleavage of the 3'-end of the Histone Pre-mRNA [Homo sapiens]
Connexin 43 hemi-channel [plasma membrane]
Connexon 26 [plasma membrane]
Connexon36 [plasma membrane]
CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm]
CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm]
Cytochrome C Binds to Apaf-1 [Homo sapiens]
Cytochrome c-mediated apoptotic response [Homo sapiens]
Cytochrome C:Apaf-1 binds Procaspase-9 [Homo sapiens]
Cytochrome C:Apaf-1:ATP:Procaspase-9 [cytosol]
damaged DNA substrate [nucleoplasm]
damaged DNA substrate:nascent mRNA hybrid [nucleoplasm]
damaged DNA substrate:nascent mRNA hybrid with 3' incision [nucleoplasm]
damaged DNA substrate:nascent mRNA hybrid with dual incisions [nucleoplasm]
damaged DNA with 3' incision [nucleoplasm]
damaged DNA with open bubble structure [nucleoplasm]
Deamination at C6 position of adenosine in Editosome (ADAR1) [Homo sapiens]
Deamination at C6 position of adenosine in Editosome (ADAR2) [Homo sapiens]
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels [Homo sapiens]
Displacement of stalled Pol II from the lesion site [Homo sapiens]
Dissociation of Caspase-3 from SMAC:XIAP:Caspase-3 [Homo sapiens]
Dissociation of Caspase-7 from SMAC:XIAP:Caspase-7 [Homo sapiens]
Dissociation of Caspase-9 from SMAC:XIAP:Caspase-9 [Homo sapiens]
Dissociation of dimeric phospho-ATM complexes [Homo sapiens]
Dissociation of the extended strands [Homo sapiens]
DNA containing Pol II promoter with transcript with 2 or 3 nucleotides [nucleoplasm]
DNA containing RNA Polymerase II promoter [nucleoplasm]
DNA Damage Recognition in GG-NER [Homo sapiens]
DNA Damage Reversal [Homo sapiens]
DNA Repair [Homo sapiens]
DNA repair synthesis [Homo sapiens]
DNA with no 6-O-methylated guanine [nucleoplasm]
DNA with RNA Polymerase III Type 1 Closed Promoter [nucleoplasm]
DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
Docking of Mature Histone mRNA complex:TAP at the NPC [Homo sapiens]
Docking of Mature Replication Dependent Histone mRNA with the NPC [Homo sapiens]
Docking of the TAP:EJC Complex with the NPC [Homo sapiens]
Double-Strand Break Repair [Homo sapiens]
downstream intronless mRNA fragment [nucleoplasm]
DSIF complex binds to RNA Pol II (hypophosphorylated) [Homo sapiens]
dsRNA duplex [nucleoplasm]
Dual incision reaction in GG-NER [Homo sapiens]
Dual incision reaction in TC-NER [Homo sapiens]
Early Phase of HIV Life Cycle [Homo sapiens]
Editosome (ADAR1) complex [nucleoplasm]
EJC complex [nucleoplasm]
Electric Transmission Across Gap Junctions [Homo sapiens]
Eukaryotic Translation Termination [Homo sapiens]
Exon Junction Complex [nucleoplasm]
Export Receptor bound mature mRNA Complex [cytosol]
Export Receptor bound mature mRNA Complex [nucleoplasm]
Fall Back to Closed Pre-initiation Complex [Homo sapiens]
FAS dimer [cytosol]
Fill-in DNA synthesis [Homo sapiens]
Formation of active Pol II complex with lesioned DNA template [Homo sapiens]
Formation of apoptosome [Homo sapiens]
Formation of AT-AC A complex [Homo sapiens]
Formation of AT-AC B Complex [Homo sapiens]
Formation of AT-AC C complex [Homo sapiens]
Formation of DSIF:NELF:early elongation complex [Homo sapiens]
Formation of dsRNA structure by looping [Homo sapiens]
Formation of editosomes by ADAR proteins [Homo sapiens]
Formation of Exon Junction Complex [Homo sapiens]
Formation of incision complex in GG-NER [Homo sapiens]
Formation of NELF complex [Homo sapiens]
Formation of open bubble structure in DNA by helicases [Homo sapiens]
Formation of RAD50:MRE11 complex [Homo sapiens]
Formation of RAD52 heptameric ring structure complexes on ssDNA [Homo sapiens]
Formation of RNA Pol II elongation complex [Homo sapiens]
Formation of stem-loop structure in ApoB mRNA [Homo sapiens]
Formation of the closed pre-initiation complex [Homo sapiens]
Formation of the Early Elongation Complex [Homo sapiens]
Formation of the Editosome [Homo sapiens]
Formation of transcription-coupled NER (TC-NER) repair complex [Homo sapiens]
Gap junction trafficking and regulation [Homo sapiens]
Gap-filling DNA repair synthesis and ligation in GG-NER [Homo sapiens]
Gap-filling DNA repair synthesis and ligation in TC-NER [Homo sapiens]
Gene Expression [Homo sapiens]
GJA1 [plasma membrane] UKENBCdOOOOORHPGURH
GJD2 [plasma membrane] UKENBCdORHPGUR
Global Genomic NER (GG-NER) [Homo sapiens]
GTF2A1(1-274) [nucleoplasm] UKENBCdORHPGPURRD
GTF2A1(275-376) [nucleoplasm] UKENBCdORHPGPURRD
GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex [Homo sapiens]
GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex [Homo sapiens]
helicase activity of TFIIH [nucleoplasm]
HIV Infection [Homo sapiens]
HIV Life Cycle [Homo sapiens]
Homologous DNA pairing and strand exchange [Homo sapiens]
Homologous Recombination Repair [Homo sapiens]
Homologous recombination repair of replication-independent double-strand breaks [Homo sapiens]
Host Interactions of HIV factors [Homo sapiens]
Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Homo sapiens]
Import of PIC to the Host Nucleus [Homo sapiens]
Incision complex with 3'-incised damaged DNA [nucleoplasm]
incision complex for GG-NER [nucleoplasm]
Integration of provirus [Homo sapiens]
Intermolecular autophosphorylation of ATM within dimeric ATM complexes [Homo sapiens]
Intrinsic Pathway for Apoptosis [Homo sapiens]
intronless pre-mRNA cleavage complex [nucleoplasm]
lariat containing 5'-end cleaved mRNA [nucleoplasm]
lariat containing 5'-end cleaved mRNA:CBC complex [nucleoplasm]
Late Phase of HIV Life Cycle [Homo sapiens]
Ligation of DNA and formation of Holliday structures following repair synthesis [Homo sapiens]
Ligation of newly synthesized repair patch to incised DNA in GG-NER [Homo sapiens]
Ligation of newly synthesized repair patch to incised DNA in TC-NER [Homo sapiens]
MAGOH [cytosol] UKENBCdORHPGPPPPURDDDD
MAGOH [nucleoplasm] UKENBCdORHPGPPPPURDDDD
Magoh-Y14 complex [cytosol]
Magoh-Y14 complex [nucleoplasm]
Mature intronless derived mRNA [cytosol]
Mature intronless derived mRNA complex [nucleoplasm]
Mature intronless transcript derived Histone mRNA [cytosol]
Mature intronless transcript derived mRNA [nucleoplasm]
Mature Intronless Transcript Derived mRNA:eIF4E Complex [cytosol]
mature mRNA [nucleoplasm]
MDC1/NFBD1 associates with gamma H2AX at nuclear foci [Homo sapiens]
MetC-MGMT [nucleoplasm] UKENBCdOORHPGPPPPPPPURDDDDDDDZH
methylated-DNA-[protein]-cysteine S-methyltransferase activity of MGMT [nucleoplasm]
MGMT/hAGT mediated DNA Damage Reversal [Homo sapiens]
MRN complex relocalizes to nuclear foci [Homo sapiens]
mRNA [cytosol] C
mRNA Editing [Homo sapiens]
mRNA Editing: A to I Conversion [Homo sapiens]
mRNA Editing: C to U Conversion [Homo sapiens]
mRNA Splicing [Homo sapiens]
mRNA Splicing - Minor Pathway [Homo sapiens]
Myristoylation of Nef [Homo sapiens]
NCBP1 [cytosol] UKENBCdORHPGPPPPPPURDDDDDD
NCBP2 [cytosol] UKENBCdORRHHPGPPPPPPURDDDDDD
Neuronal System [Homo sapiens]
Neurotransmitter Clearance In The Synaptic Cleft [Homo sapiens]
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell [Homo sapiens]
Neurotransmitter Release Cycle [Homo sapiens]
Neurotransmitter uptake and Metabolism In Glial Cells [Homo sapiens]
Newly Formed Phosphodiester Bond Stabilized and PPi Released [Homo sapiens]
newly synthesized DNA fragment [nucleoplasm]
NFX.1 [cytosol] UENBCdORRHHPGURR
NFX.1 [nucleoplasm] UENBCdORRHHPGURR
Nonhomologous End-joining (NHEJ) [Homo sapiens]
NTP Binds Active Site of RNA Polymerase II [Homo sapiens]
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP [Homo sapiens]
Nucleotide Excision Repair [Homo sapiens]
Open DNA -10 to +2 containing RNA Polymerase II promoter [nucleoplasm]
Oxidative demethylation of 1-EtA damaged DNA By ABH2 [Homo sapiens]
Oxidative demethylation of 1-EtA damaged DNA By ABH3 [Homo sapiens]
Oxidative demethylation of 1-MeA damaged DNA By ABH2 [Homo sapiens]
Oxidative demethylation of 1-MeA damaged DNA By ABH3 [Homo sapiens]
Oxidative demethylation of 3-MeC damaged DNA By ABH2 [Homo sapiens]
Oxidative demethylation of 3-MeC damaged DNA By ABH3 [Homo sapiens]
PAK1 [cytosol] UKENBCdORHPGPPPPPURDDDDDZH
phospho-ATM (Serine 1981) associates with DNA at the site of double-strand breaks [Homo sapiens]
pol II closed pre-initiation complex [nucleoplasm]
Pol II elongation complex moves on the template as transcript elongates [Homo sapiens]
pol II open pre-initiation complex [nucleoplasm]
pol II promoter:TFIID complex [nucleoplasm]
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm]
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm]
pol II transcription complex [nucleoplasm]
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm]
Pol II transcription complex containing transcript to +30 [nucleoplasm]
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm]
Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex [Homo sapiens]
post exon ligation complex [nucleoplasm]
Post-Elongation Processing of Intron-Containing pre-mRNA [Homo sapiens]
Post-Elongation Processing of Intronless pre-mRNA [Homo sapiens]
Post-Elongation Processing of the Transcript [Homo sapiens]
pre-EJC complex [nucleoplasm]
pre-incision complex in GG-NER [nucleoplasm]
pre-incision complex with open DNA bubble [nucleoplasm]
Presynaptic phase of homologous DNA pairing and strand exchange [Homo sapiens]
Processing of Capped Intron-Containing Pre-mRNA [Homo sapiens]
Processing of Capped Intronless Pre-mRNA [Homo sapiens]
Processing of DNA double-strand break ends [Homo sapiens]
Processing of DNA ends prior to end rejoining [Homo sapiens]
PRPF8 [nucleoplasm] UKENBCdOOORHPGUR
RBM8A [cytosol] UKENBCdOORHPGPPPPURDDDD
RBM8A [nucleoplasm] UKENBCdOORHPGPPPPURDDDD
Recognition and Binding of Core Promoter Elements by TFIID [Homo sapiens]
Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [Homo sapiens]
Recruitment of elongation factors to form elongation complex [Homo sapiens]
Recruitment of repair and signaling proteins to double-strand breaks [Homo sapiens]
Recruitment of repair factors to form preincision complex [Homo sapiens]
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex [Homo sapiens]
Recruitment of TAP to the EJC [Homo sapiens]
Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA [Homo sapiens]
Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA [Homo sapiens]
Release from the NPC and Disassembly of the mRNP [Homo sapiens]
Release of apoptotic factors from the mitochondria [Homo sapiens]
Release of Cytochrome c from mitochondria [Homo sapiens]
Release of SMAC from mitochondria [Homo sapiens]
Removal of repair proteins and ligation of the processed ends of the DNA double-strand break [Homo sapiens]
Repair synthesis for gap-filling by DNA pol delta in TC-NER [Homo sapiens]
Repair synthesis for gap-filling by DNA pol epsilon in TC-NER [Homo sapiens]
Repair synthesis for gap-filling by DNA polymerase in TC-NER [Homo sapiens]
Repair synthesis of patch ~27-30 bases long by DNA Pol Delta [Homo sapiens]
Repair synthesis of patch ~27-30 bases long by DNA polymerase [Homo sapiens]
Repair synthesis of ~27-30 bases long patch by DNA Pol Epsilon [Homo sapiens]
repaired DNA template:nascent mRNA hybrid [nucleoplasm]
Repaired double-stranded DNA [nucleoplasm]
Resection of double-strand break ends [Homo sapiens]
Resolution of D-loop structures [Homo sapiens]
Resolution of D-loop structures through Holliday junction intermediates [Homo sapiens]
Resolution of D-loop structures through synthesis-dependent strand-annealing [Homo sapiens]
Resumption of elongation after recovery from pausing [Homo sapiens]
Resumption of transcription after TC-NER [Homo sapiens]
Reversal of Alkylation Damage By DNA Dioxygenases [Homo sapiens]
Reverse Transcription of HIV RNA [Homo sapiens]
RNA Pol II is blocked by the lesion leading to reduced transcription [Homo sapiens]
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm]
RNA Polymerase II Promoter Escape [Homo sapiens]
RNA Polymerase II Promoter Opening: First Transition [Homo sapiens]
RNA Polymerase II Transcription [Homo sapiens]
RNA Polymerase II Transcription Elongation [Homo sapiens]
RNA Polymerase II Transcription Initiation [Homo sapiens]
RNA Polymerase II Transcription Initiation And Promoter Clearance [Homo sapiens]
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening [Homo sapiens]
RNA Polymerase II Transcription Termination [Homo sapiens]
RNA Polymerase III Transcription [Homo sapiens]
RNA Polymerase III Transcription Initiation [Homo sapiens]
RNA Polymerase III Transcription Initiation From Type 1 Promoter [Homo sapiens]
RNA Polymerase III Transcription Initiation From Type 2 Promoter [Homo sapiens]
RNA Polymerase III Transcription Initiation From Type 3 Promoter [Homo sapiens]
RNPS1 [cytosol] UKENNNBBBCCCdddORRHHPGURR
RNPS1 [nucleoplasm] UKENNNBBBCCCdddORRHHPGURR
S-methyl-L-cysteine at 145
Separation of elongating transcript from template [Homo sapiens]
SF3B14 [nucleoplasm] UKENBCdORHPGPPURDD
Signal Transduction [Homo sapiens]
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs [Homo sapiens]
SLBP independent Processing of Histone Pre-mRNAs [Homo sapiens]
SMAC binds to IAPs [Homo sapiens]
SMAC binds XIAP:Caspase-3 [Homo sapiens]
SMAC binds XIAP:Caspase-7 [Homo sapiens]
SMAC binds XIAP:Caspase-9 [Homo sapiens]
SMAC-mediated apoptotic response [Homo sapiens]
SMAC-mediated dissociation of IAP:caspase complexes [Homo sapiens]
SMAC:XIAP [cytosol]
Spliceosomal active C complex with lariat containing, 5'-end cleaved pre-mRNP:CBC complex [nucleoplasm]
SRRM1 [cytosol] UKENBCdORHPGPURD
SRRM1 [nucleoplasm] UKENBCdORHPGPURD
Stalled Pol II complex with damaged DNA hybrid [nucleoplasm]
Stalled Pol II in TC-NER [nucleoplasm]
Strand exchange/Branch migration [Homo sapiens]
Synapsis, or interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB [Homo sapiens]
TAP:3'-polyadenylated, capped mRNA complex [nucleoplasm]
Telomere Maintenance [Homo sapiens]
template DNA with first transcript dinucleotide, opened to +8 position [nucleoplasm]
template DNA:30 nt transcript hybrid [nucleoplasm]
template DNA:4 nucleotide transcript hybrid [nucleoplasm]
TFIIA [nucleoplasm]
TFIID [nucleoplasm]
TFIIE [nucleoplasm]
TFIIF [nucleoplasm]
TFIIH [nucleoplasm]
TFIIIA:Type 1 Promoter complex [nucleoplasm]
TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex [nucleoplasm]
TFIIIC:TFIIIA:Type I Promoter Complex [nucleoplasm]
TNF-alpha:TNFR1 [plasma membrane]
Transcription [Homo sapiens]
Transcription-coupled NER (TC-NER) [Homo sapiens]
Translation [Homo sapiens]
Transmission across Chemical Synapses [Homo sapiens]
Transmission across Electrical Synapses [Homo sapiens]
Transport of Mature Transcript to Cytoplasm [Homo sapiens]
Transport of the export-competent complex through the NPC [Homo sapiens]
U11 snRNA [nucleoplasm]
U11 snRNP [nucleoplasm]
U12 snRNA [nucleoplasm]
U12 snRNP [nucleoplasm]
U4 ATAC snRNA [nucleoplasm]
U4 ATAC snRNP [nucleoplasm]
U4 ATAC snRNP:U6 ATAC snRNP [nucleoplasm]
U4 ATAC:U5:U6 ATAC Complex [nucleoplasm]
U4:U5:U6 trisnRNP complex [nucleoplasm]
U6 ATAC snRNA [nucleoplasm]
U6 ATAC snRNP [nucleoplasm]
Uncoating of the HIV Virion [Homo sapiens]
UPF3B [cytosol] UKENBCdORHPGPURD
UPF3B [nucleoplasm] UKENBCdORHPGPURD
upstream intronless mRNA fragment [nucleoplasm]
upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm]
XPC binds to HR23B forming a heterodimeric complex [Homo sapiens]
XPC:HR23B complex binds to damaged DNA site with lesion [Homo sapiens]
XPC:HR23B:damaged DNA complex [nucleoplasm]