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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Morrison, CJ, Butler, GS, Bigg, HF, Roberts, CR, Soloway, PD, Overall, CM Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway 2001 J Biol Chem PubMed
Tam, EM, Wu, YI, Butler, GS, Stack, MS, Overall, CM Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage 2002 J Biol Chem PubMed
Morrison, CJ, Butler, GS, RodrĂ­guez, D, Overall, CM Matrix metalloproteinase proteomics: substrates, targets, and therapy 2009 Curr Opin Cell Biol PubMed
Butler, GS, Will, H, Atkinson, SJ, Murphy, G Membrane-type-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases 1997 Eur J Biochem PubMed
Butler, GS, Butler, MJ, Atkinson, SJ, Will, H, Tamura, T, Schade van Westrum, S, Crabbe, T, Clements, J, d'Ortho, MP, Murphy, G The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study 1998 J Biol Chem PubMed
Bigg, HF, Morrison, CJ, Butler, GS, Bogoyevitch, MA, Wang, Z, Soloway, PD, Overall, CM Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase 2001 Cancer Res PubMed
Butler, GS, Overall, CM Updated biological roles for matrix metalloproteinases and new "intracellular" substrates revealed by degradomics 2009 Biochemistry PubMed
Kai, HS, Butler, GS, Morrison, CJ, King, AE, Pelman, GR, Overall, CM Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding the MMP-2 hemopexin C-domain 2002 J Biol Chem PubMed