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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
First nameStephen H
AffiliationNCI - Frederick, HIV Drug Resistance Program
Hughes, SH, Mutschler, A, Bishop, JM, Varmus, HE A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration 1981 Proc Natl Acad Sci U S A PubMed
Jacobo-Molina, A, Ding, J, Nanni, RG, Clark AD, Jr, Lu, X, Tantillo, C, Williams, RL, Kamer, G, Ferris, AL, Clark, P, Hizi, A, Arnold, E, Hughes, SH Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. 1993 Proc Natl Acad Sci U S A PubMed
Julias, JG, McWilliams, MJ, Sarafianos, SG, Alvord, WG, Arnold, E, Hughes, SH Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage 2004 J Virol PubMed
Driscoll, MD, Hughes, SH Human immunodeficiency virus type 1 nucleocapsid protein can prevent self-priming of minus-strand strong stop DNA by promoting the annealing of short oligonucleotides to hairpin sequences 2000 J Virol PubMed
Coffin, JM, Hughes, SH, Varmus, HE Integration 1997 Retroviruses (Book) Integration
Hughes, SH, Shank, PR, Spector, DH, Kung, HJ, Bishop, JM, Varmus, HE, Vogt, PK, Breitman, ML Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites 1978 Cell PubMed
Whitcomb, JM, Hughes, SH Retroviral reverse transcription and integration: progress and problems 1992 Annu Rev Cell Biol PubMed
Coffin, JM, Hughes, SH, Varmus, HE Retroviruses 1997 Retroviruses (CSHL Press) Retroviruses
Ghosh, M, Howard, KJ, Cameron, CE, Benkovic, SJ, Hughes, SH, Le Grice, SF Truncating alpha-helix E' of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer 1995 J Biol Chem PubMed
Hughes, SH, Hostomsky, Z, Le Grice, SF, Lentz, K, Arnold, E What is the orientation of DNA polymerases on their templates? 1996 J Virol PubMed