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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
First nameLena
AffiliationUppsala University, Department of Genetics and Pathology
Valgeirsdóttir, S, Paukku, K, Silvennoinen, O, Heldin, CH, Claesson-Welsh, L Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains 1998 Oncogene PubMed
Sasaki, T, Larsson, H, Tisi, D, Claesson-Welsh, L, Hohenester, E, Timpl, R Endostatins derived from collagens XV and XVIII differ in structural and binding properties, tissue distribution and anti-angiogenic activity 2000 J Mol Biol PubMed
Yokote, K, Margolis, B, Heldin, CH, Claesson-Welsh, L Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors 1996 J Biol Chem PubMed
Rönnstrand, L, Mori, S, Arridsson, AK, Eriksson, A, Wernstedt, C, Hellman, U, Claesson-Welsh, L, Heldin, CH Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma 1992 EMBO J PubMed
Mori, S, Rönnstrand, L, Yokote, K, Engström, A, Courtneidge, SA, Claesson-Welsh, L, Heldin, CH Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases 1993 EMBO J PubMed
Ito, N, Wernstedt, C, Engstrom, U, Claesson-Welsh, L Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules 1998 J Biol Chem PubMed
Dixelius, J, Makinen, T, Wirzenius, M, Karkkainen, MJ, Wernstedt, C, Alitalo, K, Claesson-Welsh, L Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites 2003 J Biol Chem PubMed
Hawkins, PT, Eguinoa, A, Qiu, RG, Stokoe, D, Cooke, FT, Walters, R, Wennström, S, Claesson-Welsh, L, Evans, T, Symons, M PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase 1995 Curr Biol PubMed
Klint, P, Kanda, S, Claesson-Welsh, L Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells 1995 J Biol Chem PubMed
Koch, S, Claesson-Welsh, L Signal transduction by vascular endothelial growth factor receptors 2012 Cold Spring Harb Perspect Med PubMed
Shibuya, M, Claesson-Welsh, L Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis 2006 Exp Cell Res PubMed
Ong, SH, Goh, KC, Lim, YP, Low, BC, Klint, P, Claesson-Welsh, L, Cao, X, Tan, YH, Guy, GR Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2 1996 Biochem Biophys Res Commun PubMed
Holmqvist, K, Cross, MJ, Rolny, C, Hägerkvist, R, Rahimi, N, Matsumoto, T, Claesson-Welsh, L, Welsh, M The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration 2004 J. Biol. Chem. PubMed
Arvidsson, AK, Rupp, E, Nånberg, E, Downward, J, Rönnstrand, L, Wennström, S, Schlessinger, J, Heldin, CH, Claesson-Welsh, L Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation 1994 Mol Cell Biol PubMed
Cross, MJ, Hodgkin, MN, Roberts, S, Landgren, E, Wakelam, MJ, Claesson-Welsh, L Tyrosine 766 in the fibroblast growth factor receptor-1 is required for FGF-stimulation of phospholipase C, phospholipase D, phospholipase A(2), phosphoinositide 3-kinase and cytoskeletal reorganisation in porcine aortic endothelial cells 2000 J Cell Sci PubMed
Olsson, AK, Dimberg, A, Kreuger, J, Claesson-Welsh, L VEGF receptor signalling - in control of vascular function 2006 Nat Rev Mol Cell Biol PubMed
Matsumoto, T, Bohman, S, Dixelius, J, Berge, T, Dimberg, A, Magnusson, P, Wang, L, Wikner, C, Qi, JH, Wernstedt, C, Wu, J, Bruheim, S, Mugishima, H, Mukhopadhyay, D, Spurkland, A, Claesson-Welsh, L VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis 2005 EMBO J. PubMed
Cross, MJ, Dixelius, J, Matsumoto, T, Claesson-Welsh, L VEGF-receptor signal transduction 2003 Trends Biochem Sci PubMed
Claesson-Welsh, L, Welsh, M VEGFA and tumour angiogenesis 2013 J. Intern. Med. PubMed
Sun, Z, Li, X, Massena, S, Kutschera, S, Padhan, N, Gualandi, L, Sundvold-Gjerstad, V, Gustafsson, K, Choy, WW, Zang, G, Quach, M, Jansson, L, Phillipson, M, Abid, MR, Spurkland, A, Claesson-Welsh, L VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd 2012 J. Exp. Med. PubMed