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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P46527
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Cyclin-dependent kinase inhibitor 1B alternativeName: Cyclin-dependent kinase inhibitor p27 alternativeName: p27Kip1
Links to corresponding entries in other databasesBioGPS Gene:1027
CTD Gene:1027
DOCK Blaster:1H27
DOCK Blaster:1JSU
DOCK Blaster:2AST
ENSEMBL:ENSG00000111276
GeneCards:P46527
HapMap:NM_004064
KEGG Gene:1027
NCBI Gene:1027
OMIM:600778
OMIM:610755
Protein Data Bank:1H27
Protein Data Bank:1JSU
Protein Data Bank:2AST
RefSeq:NM_004064
RefSeq:NP_004055
UCSC human:P46527
UniProt:P46527
dbSNP Gene:1027
Other identifiers related to this sequenceCDN1B_HUMAN, Q16307, Q5U0H2, Q9BUS6, ENSG00000111276, ENST00000228872, ENSP00000228872, 2034_s_at, 209112_at, 33847_s_at, 33848_r_at, 52535_s_at, 69792_r_at, g12805034_3p_at, A_14_P102019, A_23_P204696, A_24_P81841, CCDS8653, GE81344, X84849, AJ616234, AF247551, CR457399, AY004255, AF213700, BT019553, BT019554, U10906, S76988, S76986, AF480891, BC001971, EntrezGene:1027, GI_17978497-S, ILMN_6132, IPI00853130, IPI00006991, MIM:600778, MIM:610755, OTTHUMP00000195100, OTTHUMT00000313880, 1H27, 1JSU, 2AST, CAA59284, CAE82383, AAF69497, CAG33680, AAF88142, AAF21058, AAV38360, AAV38361, AAA20240, AAD14244, AAL78041, AAH01971, NM_004064, NP_004055, OTTHUMT00000313878, Hs.238990, Hs.593269, Hs.628402, Hs.697066, O43806, Q708J1, Q9NYG6, Q6I9V6, Q96TE0, Q9UH60, Q5U0H2, P46527, O43806_HUMAN, Q708J1_HUMAN, Q9NYG6_HUMAN, Q6I9V6_HUMAN, Q96TE0_HUMAN, Q9UH60_HUMAN, Q5U0H2_HUMAN, CDN1B_HUMAN, IPR003175
Molecules with this sequenceCDKN1B [nucleoplasm] UKENBCdOORHGURPPPDDD
p-T187-CDKN1B [nucleoplasm] UKENBCdOORHGURPPPDDD
CDKN1B [cytosol] UKENBCdOORHGURPPPDDD
p-T157-CDKN1B [cytosol] UKENBCdOORHGURPPPDDD
Component ofCyclin E:Cdk2:p21/p27 complex [nucleoplasm]
Cyclin D:phospho-CDK4/6:p21/p27 [nucleoplasm]
Cyclin D:Cdk4/6:p21/p27 [nucleoplasm]
Cyclin E/A:Cdk2:p27/p21 complex [nucleoplasm]
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
Cyclin A:Cdk2:substrate complex [nucleoplasm]
Cyclin E/A:Cdk2:phospho-p27/p21 [nucleoplasm]
Cyclin A:Cdk2:phospho-p27/p21 complex [nucleoplasm]
Cyclin A:Cdk2:phosphorylated substrate complex [nucleoplasm]
Cyclin D:CDK4/6:p21/p27 complex [cytosol]
...
List all 12 items
Represented by generalisation(s)p21/p27 [nucleoplasm]
Cyclin A:Cdk1 substrate proteins [nucleoplasm]
phospho-p27/p21 [nucleoplasm]
phosphorylated Cyclin A:Cdk2 substrate proteins [nucleoplasm]
p21/p27 [cytosol]
CDKN1A/B [cytosol]
p-T-CDKN1A/B [cytosol]
Processes where molecules and complexes with this sequence are involved

Immune System

Signal Transduction

DNA Replication

Cell Cycle

Cellular responses to stress

Disease

Modifications in molecules with this sequenceO-phospho-L-threonine at 187
O-phospho-L-threonine at 157
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