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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P46527
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Cyclin-dependent kinase inhibitor 1B alternativeName: Cyclin-dependent kinase inhibitor p27 alternativeName: p27Kip1
Links to corresponding entries in other databasesBioGPS Gene:1027
CTD Gene:1027
DOCK Blaster:1H27
DOCK Blaster:1JSU
DOCK Blaster:2AST
ENSEMBL:ENSG00000111276
GeneCards:P46527
HapMap:NM_004064
KEGG Gene:1027
NCBI Gene:1027
OMIM:600778
OMIM:610755
Orphanet:18426
PRO:P46527
Protein Data Bank:1H27
Protein Data Bank:1JSU
Protein Data Bank:2AST
RefSeq:NM_004064
RefSeq:NP_004055
UCSC human:P46527
UniProt:P46527
dbSNP Gene:1027
Other identifiers related to this sequenceCDN1B_HUMAN, Q16307, Q5U0H2, Q9BUS6, 2AST, Hs.238990, CDKN1B, CAB021888, 7954029, 1H27, 3405455, 1027, 8033212, 3405445, 3405456, HGNC:1785, 2034_s_at, BT019554, AAV38360, 3405446, BAG70237, S76988, BAG70105, AAH01971, CAG33680, BC001971, Q6I9V6, AB451423, AF213700, 33847_s_at, g12805034_3p_at, AK298335, 11748603_a_at, 1JSU, AAV38361, CAB003691, MIM:600778, AB451291, ENSG00000111276, BT019553, 33848_r_at, AAL78041, MIM:610755, ENSP00000228872, CR457399, UPI0000035C92, Q9UH60, PH_hs_0012886, A_14_P102019, AAD14244, A_23_P204696, 0002100280, BAG35368, AF480891, IPR003175, 16748477, NM_004064, 3405449, B4DPH2, BAG60584, EntrezGene:1027, AAF21058, Hs.628402, CCDS8653, EAW96275, 52535_s_at, S76986, OTTHUMP00000195098, Hs.593269, AAA20240, ILMN_2196347, 11717091_s_at, 209112_at, CH471094, ILMN_1722811, A_24_P81841, GE81344, uc001rat.2, CDKN1B-001, U10906, AK312461, NP_004055, PF02234
Molecules with this sequenceCDKN1B [nucleoplasm] UKENBCdOOORHPGPPPURDDD
p-T187-CDKN1B [nucleoplasm] UKENBCdOOORHPGPPPURDDD
CDKN1B [cytosol] UKENBCdOOORHPGPPPURDDD
p-T157-CDKN1B [cytosol] UKENBCdOOORHPGPPPURDDD
Component ofCyclin E:Cdk2:p21/p27 complex [nucleoplasm]
Cyclin D:phospho-CDK4/6:p21/p27 [nucleoplasm]
Cyclin D:Cdk4/6:p21/p27 [nucleoplasm]
Cyclin E/A:Cdk2:p27/p21 complex [nucleoplasm]
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
Cyclin A:Cdk2:substrate complex [nucleoplasm]
Cyclin E/A:Cdk2:phospho-p27/p21 [nucleoplasm]
Cyclin A:Cdk2:phospho-p27/p21 complex [nucleoplasm]
Cyclin A:Cdk2:phosphorylated substrate complex [nucleoplasm]
Cyclin D:CDK4/6:p21/p27 complex [cytosol]
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List all 12 items
Represented by generalisation(s)p21/p27 [nucleoplasm]
Cyclin A:Cdk1 substrate proteins [nucleoplasm]
phospho-p27/p21 [nucleoplasm]
phosphorylated Cyclin A:Cdk2 substrate proteins [nucleoplasm]
p21/p27 [cytosol]
CDKN1A/B [cytosol]
p-T-CDKN1A/B [cytosol]
Processes where molecules and complexes with this sequence are involved

Immune System

Signal Transduction

DNA Replication

Cell Cycle

Cellular responses to stress

Disease

Modifications in molecules with this sequenceO-phospho-L-threonine at 187
O-phospho-L-threonine at 157
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