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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P0C0L4
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Complement C4-A alternativeName: Acidic complement C4 alternativeName: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 component recommendedName: Complement C4 beta chain /component component recommendedName: Complement C4-A alpha chain /component component recommendedName: C4a anaphylatoxin /component component recommendedName: C4b-A /component component recommendedName: C4d-A /component component recommendedName: Complement C4 gamma chain /component
Links to corresponding entries in other databasesKEGG Gene:721
BioGPS Gene:720
CTD Gene:720
DOCK Blaster:1HZF
ENSEMBL:ENSG00000204319
GeneCards:P0C0L4
HapMap:NM_007293
KEGG Gene:720
NCBI Gene:720
OMIM:120790
OMIM:120810
OMIM:120820
Orphanet:17447
PRO:P0C0L4
Protein Data Bank:1HZF
RefSeq:NM_007293
RefSeq:NP_009224
UCSC human:P0C0L4
UniProt:P0C0L4
dbSNP Gene:720
Other identifiers related to this sequenceCO4A_HUMAN, A6H8M8, A6NHJ5, A7E2V2, B0QZR6, B0V2C8, B2RUT6, B7ZVZ6, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q4LE82, Q5JNX2, Q5JQM8, Q6P4R1, Q6U2E5, Q6U2E8, Q6U2F0, Q6U2F3, Q6U2F4, Q6U2F6, Q6U2F8, Q6U2G0, Q96EG2, Q96SA8, Q9NPK5, Q9UIP5, ENSG00000244731, AAB63422, AAH12372, AY379930, MIM:152700, 2902978, AY379913, C4B, 2903003, NM_007293, AAR89141, 17030967, 2902983, PH_hs_0031857, 2902998, MIM:120790, PR00004, AAH63289, 8118455, AL929593, BC151204, 2902964, AY379961, AAR89165, S81585, AY379934, PF07677, AY379915, 214428_x_at, CCDS47404, 17007048, IPR018933, BC012372, 4FXK, AAR89146, 8118409, AY379925, ILMN_2179533, AY379928, AAI71786, 2902973, 2903007, AAR89153, 2902993, 11734747_a_at, 17035749, 2903015, 2902967, BC146673, AY379968, Hs.534847, IPR002890, 2903002, AY379897, AAR89112, AAA51855, AY379891, CR936924, 2902979, AY379967, 17041030, CAB032603, 2903024, AY379931, AY379963, 720, AY379885, M59815, Q6U2E0, 2903026, 2903004, U07855, AL844853, AAR89126, PF01759, 2903022, 2902974, Q6U2K2, AAR89108, 2902984, AY379881, AY379921, 40766_at, AAR89152, AAR89157, 2902988, MIM:614374, AAA20121, AAR89159, AY379960, 2903017, 8179399, IPR018081, 2902989, AAR89160, AAR89147, GE62331, HPA046356, AAK49810, X77491, SM00643, AAR89166, M59816, AY379935, 2902963, AY379887, AAR89143, 2903000, AAR89118, ILMN_1813695, 2902980, AAR89170, AAB63418, AAR89158, PF01835, AAR89173, 2902960, AAR89120, 74611_s_at, K02403, 2903006, 2902966, EntrezGene:720, AY379927, V00502, AAI46674, PF07678, BC146849, AAR89149, 2903020, ILMN_1715109, 11754270_a_at, IPR011626, IPR001840, 2902997, AY379966, AAR89169, 2902969, AAI44547, g5579450_3p_s_at, 2902970, IPR008930, BC144546, 2902975, 2902981, Q9UM89, U07851, PF10569, NP_009224, AY379970, AAI46850, 17031045, AAR89156, C4A-001, IPR011625, AAR89172, AY379962, LRG_137, 2903005, AY379932, AAR89167, 2903027, A_23_P42282, AAR89161, AAA52292, ENST00000428956, AY379889, IPR009048, ZA, LRG_137t1, 2902962, 2902985, BC171786, AAR89155, V9H0D6, 2902991, 0004280167, AY379933, AY379926, BC063289, AAB59537, MIM:120810, AAR89114, AAR89171, Q6U2E7, BAE06071, AY379899, 17041111, AY379893, IPR001599, 2902999, M59815_at, SM00104, AY379965, L26261, PF07703, uc011doy.2, AY379917, 2903018, 2903010, HPA050103, 1HZF, HGNC:1323, AAB36122, CAB009811, ENSP00000420212, 2903012, IPR008993, AAR89140, ENST00000498271, 2902976, OTTHUMP00000029266, AAI51205, AY379923, AAR89124, HPA048287, 4FXG, UPI00001AF648, AY379964, 2902961, C4A, 17038462, AY379895, CAA23760, U07852, U07853, 2902986, 11749926_a_at, AAR89168, 2902965, 0000580121, U77886, AAR89162, PF00207, AAB63419, AY379883, K00830, AY379929, 2902982, IPR008964, PF01821, AAR89175, AY379971, AAR89174, Q9UMV1, AL645922, AAB63420, ENSP00000396688, IPR019565, AAR89164, M14824, AB209989, 2903009, IPR000020, MIM:614380, AY379969, 2902977, AAR89110, AAR89154, 2903028, 2902994, 17007118, 2902995, 2902972, 208451_s_at, CAA54627, AY379919, 17028176, IPR001134, AAA36229, AAR89122, 2902959, A_14_P137370, AAR89116, C4A-013, CCDS59005, uc011doz.2, UPI0001574E5D, OTTHUMP00000216221, NP_001239133, NM_001252204, UPI00004A3B2C, ENSG00000206340, ENSP00000372815, OTTHUMP00000014606, OTTHUMP00000194382, ENSG00000227746, UPI000165DC7C, ENSP00000388662
Molecules with this sequenceC4 alpha [extracellular region] UKKENBCdOOOORHPGPURD
C4A gamma [extracellular region] UKKENBCdOOOORHPGPURD
C4A beta [extracellular region] UKKENBCdOOOORHPGPURD
C4A alpha b [extracellular region] UKKENBCdOOOORHPGPURD
C4A-derived C4a [extracellular region] UKKENBCdOOOORHPGPURD
C4A(956-1336) [plasma membrane] UKKENBCdOOOORHPGPURD
C4A alpha3 [extracellular region] UKKENBCdOOOORHPGPURD
C4A alpha4 fragment [extracellular region] UKKENBCdOOOORHPGPURD
dNQ-C4A(757-1446) [extracellular region] UKKENBCdOOOORHPGPURD
Component ofComplement factor 4A [extracellular region]
C4A-derived C4c [extracellular region]
thioester-C1010-Q1013- C4A-derived C4b [extracellular region]
deamidated-Q1013-C4A-derived C4b [extracellular region]
C4-binding protein:C4b [plasma membrane]
Cell surface:C4b [plasma membrane]
C4b-binding protein:Factor I [plasma membrane]
Cell surface:C4b:C2a [plasma membrane]
DAF:C4b [plasma membrane]
CD46:C4b [plasma membrane]
...
List all 16 items
Represented by generalisation(s)C4a [extracellular region]
C4d [plasma membrane]
C4d, iC3b [plasma membrane]
Processes where molecules and complexes with this sequence are involved

Immune System

Modifications in molecules with this sequencedeamidated L-glutamine at 1013
Intra-chain Crosslink via S-(L-isoglutamyl)-L-cysteine at 1010 and 1013
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