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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P10145
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Interleukin-8 shortName:IL-8 alternativeName: C-X-C motif chemokine 8 alternativeName: Chemokine (C-X-C motif) ligand 8 alternativeName: Emoctakin alternativeName: Granulocyte chemotactic protein 1 shortName:GCP-1 alternativeName: Monocyte-derived neutrophil chemotactic factor shortName:MDNCF alternativeName: Monocyte-derived neutrophil-activating peptide shortName:MONAP alternativeName: Neutrophil-activating protein 1 shortName:NAP-1 alternativeName: Protein 3-10C alternativeName: T-cell chemotactic factor component recommendedName: MDNCF-a alternativeName: GCP/IL-8 protein IV alternativeName: IL8/NAP1 form I /component component recommendedName: Interleukin-8 alternativeName: (Ala-IL-8)77 alternativeName: GCP/IL-8 protein II alternativeName: IL-8(1-77) alternativeName: IL8/NAP1 form II alternativeName: MDNCF-b /component component recommendedName: IL-8(5-77) /component component recommendedName: IL-8(6-77) alternativeName: (Ser-IL-8)72 alternativeName: GCP/IL-8 protein I alternativeName: IL8/NAP1 form III alternativeName: Lymphocyte-derived neutrophil-activating factor shortName:LYNAP alternativeName: MDNCF-c alternativeName: Neutrophil-activating factor shortName:NAF /component component recommendedName: IL-8(7-77) alternativeName: GCP/IL-8 protein V alternativeName: IL8/NAP1 form IV /component component recommendedName: IL-8(8-77) alternativeName: GCP/IL-8 protein VI alternativeName: IL8/NAP1 form V /component component recommendedName: IL-8(9-77) alternativeName: GCP/IL-8 protein III alternativeName: IL8/NAP1 form VI /component
Links to corresponding entries in other databasesBioGPS Gene:3576
CTD Gene:3576
DOCK Blaster:1ICW
DOCK Blaster:1IKL
DOCK Blaster:1IKM
DOCK Blaster:1IL8
DOCK Blaster:1ILP
DOCK Blaster:1ILQ
DOCK Blaster:1QE6
DOCK Blaster:1ROD
DOCK Blaster:2IL8
DOCK Blaster:3IL8
ENSEMBL:ENSG00000169429
GeneCards:P10145
HapMap:NM_000584
KEGG Gene:3576
NCBI Gene:3576
OMIM:146930
PRO:P10145
Protein Data Bank:1ICW
Protein Data Bank:1IKL
Protein Data Bank:1IKM
Protein Data Bank:1IL8
Protein Data Bank:1ILP
Protein Data Bank:1ILQ
Protein Data Bank:1QE6
Protein Data Bank:1ROD
Protein Data Bank:2IL8
Protein Data Bank:3IL8
RefSeq:NM_000584
RefSeq:NP_000575
UCSC human:P10145
UniProt:P10145
ZINC_target:P10145
dbSNP Gene:3576
Other identifiers related to this sequenceIL8_HUMAN, B2R4L8, Q6FGF6, Q6LAE6, Q96RG6, Q9C077, Q9UCE1, Q9UCR8, Q9UCR9, Q9UCS0, 11754026_a_at, EAX05688, 1IKL, BAG34815, 3IL8, CCDS34005, BT007067, A_14_P105298, AAA36323, EntrezGene:3576, M28130_rna1_s_at, AF385628, 1IL8, AAH13615, PH_hs_0043211, HGNC:6025, AAK60276, 1ILP, M28130, M26383, 1QE6, uc003hhe.3, CXCL8-001, M17017, AAA59158, ENSP00000306512, AF043337, 2731335, PR00437, 0005670500, 202859_x_at, 35372_r_at, CR542151, CH471057, GE62180, IPR001089, 3576, Hs.624, AAP35730, 1ICW, A_32_P87013, Hs.632880, A_14_P107514, PH_hs_0000069, 211506_s_at, g12641914_3p_a_at, CAG46948, UPI0000000DD0, 2731333, 1ILQ, 2731334, AK311874, 1369_s_at, CXCL8, Y00787_s_at, C9J4T6, ENSG00000169429, Y00787, NM_000584, IPR001811, Z11686, PF00048, NP_000575, HPA057179, g10834977_3p_at, 2731338, 8095680, CAA68742, AAK00048, SM00199, ILMN_2184373, 1IKM, ILMN_1666733, BC013615, CAA77745, 2IL8, 11763226_x_at, 1ROD, PR00436, MIM:146930, 2731339, D14283, 16967771, AC112518, OTTHUMP00000199824, 2731341, g10834977_3p_x_at, BAA03245, 11718841_s_at, AAA35611
Molecules with this sequenceIL8 [extracellular region] UKENBCdORHPGPPPPPPPPPPURDDDDDDDDDDZ
Component ofCXCR1:CXCR1 ligands [plasma membrane]
CXCR2:CXCR2 ligands [plasma membrane]
DARC:CXCL8 [plasma membrane]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane]
Represented by generalisation(s)CXCR2 ligands [extracellular region]
CXCR1 ligands [extracellular region]
Ligands of GPCRs that activate Gi [extracellular region]
Processes where molecules and complexes with this sequence are involved

Metabolism of proteins

Signal Transduction

Cellular responses to stress

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