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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P10145
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Interleukin-8 shortName:IL-8 alternativeName: C-X-C motif chemokine 8 alternativeName: Emoctakin alternativeName: Granulocyte chemotactic protein 1 shortName:GCP-1 alternativeName: Monocyte-derived neutrophil chemotactic factor shortName:MDNCF alternativeName: Monocyte-derived neutrophil-activating peptide shortName:MONAP alternativeName: Neutrophil-activating protein 1 shortName:NAP-1 alternativeName: Protein 3-10C alternativeName: T-cell chemotactic factor component recommendedName: MDNCF-a alternativeName: GCP/IL-8 protein IV alternativeName: IL8/NAP1 form I /component component recommendedName: Interleukin-8 alternativeName: (Ala-IL-8)77 alternativeName: GCP/IL-8 protein II alternativeName: IL-8(1-77) alternativeName: IL8/NAP1 form II alternativeName: MDNCF-b /component component recommendedName: IL-8(5-77) /component component recommendedName: IL-8(6-77) alternativeName: (Ser-IL-8)72 alternativeName: GCP/IL-8 protein I alternativeName: IL8/NAP1 form III alternativeName: Lymphocyte-derived neutrophil-activating factor shortName:LYNAP alternativeName: MDNCF-c alternativeName: Neutrophil-activating factor shortName:NAF /component component recommendedName: IL-8(7-77) alternativeName: GCP/IL-8 protein V alternativeName: IL8/NAP1 form IV /component component recommendedName: IL-8(8-77) alternativeName: GCP/IL-8 protein VI alternativeName: IL8/NAP1 form V /component component recommendedName: IL-8(9-77) alternativeName: GCP/IL-8 protein III alternativeName: IL8/NAP1 form VI /component
Links to corresponding entries in other databasesBioGPS Gene:3576
CTD Gene:3576
DOCK Blaster:1ICW
DOCK Blaster:1IKL
DOCK Blaster:1IKM
DOCK Blaster:1IL8
DOCK Blaster:1ILP
DOCK Blaster:1ILQ
DOCK Blaster:1QE6
DOCK Blaster:1ROD
DOCK Blaster:2IL8
DOCK Blaster:3IL8
ENSEMBL:ENSG00000169429
GeneCards:P10145
HapMap:NM_000584
KEGG Gene:3576
NCBI Gene:3576
OMIM:146930
Protein Data Bank:1ICW
Protein Data Bank:1IKL
Protein Data Bank:1IKM
Protein Data Bank:1IL8
Protein Data Bank:1ILP
Protein Data Bank:1ILQ
Protein Data Bank:1QE6
Protein Data Bank:1ROD
Protein Data Bank:2IL8
Protein Data Bank:3IL8
RefSeq:NM_000584
RefSeq:NP_000575
UCSC human:P10145
UniProt:P10145
dbSNP Gene:3576
Other identifiers related to this sequenceIL8_HUMAN, B2R4L8, Q6FGF6, Q6LAE6, Q96RG6, Q9C077, Q9UCE1, Q9UCR8, Q9UCR9, Q9UCS0, ENSG00000169429, ENST00000395775, ENSP00000379121, ENST00000307407, ENSP00000306512, 1369_s_at, 211506_s_at, 202859_x_at, 35372_r_at, M28130_rna1_s_at, Y00787_s_at, g10834977_3p_at, g10834977_3p_x_at, g12641914_3p_a_at, A_14_P105298, A_14_P107514, A_32_P87013, A_23_P81006, A_32_P144353, CCDS34005, GE62180, Y00787, M17017, M26383, M28130, D14283, AF043337, BT007067, CR542151, AF385628, BC013615, Z11686, EntrezGene:3576, GI_28610153-S, ILMN_2247, IPI00288914, IPI00215621, MIM:146930, 1ILP, 1ILQ, 1ROD, 1ICW, 1IKL, 1IKM, 1IL8, 1QE6, 2IL8, 3IL8, CAA68742, AAA35611, AAA36323, AAA59158, BAA03245, AAK00048, AAP35730, CAG46948, AAK60276, AAH13615, CAA77745, NM_000584, NP_000575, Hs.624, Q9UCR8, P10145, Q9UCR8_HUMAN, IL8_HUMAN, P10145-2, IPR001089, IPR002473, IPR001811
Molecules with this sequenceIL8 [extracellular region] UKENBCdORHGURPPPPPPPPPPDDDDDDDDDD
Component ofCXCR1:CXCR1 ligands [plasma membrane]
CXCR2:CXCR2 ligands [plasma membrane]
DARC:CXCL8 [plasma membrane]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane]
Represented by generalisation(s)CXCR2 ligands [extracellular region]
CXCR1 ligands [extracellular region]
Ligands of GPCRs that activate Gi [extracellular region]
Processes where molecules and complexes with this sequence are involved

Metabolism of proteins

Signal Transduction

Cellular responses to stress

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