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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P49841
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Glycogen synthase kinase-3 beta shortName:GSK-3 beta ecNumber2.7.11.26/ecNumber alternativeName: Serine/threonine-protein kinase GSK3B ecNumber2.7.11.1/ecNumber
Links to corresponding entries in other databasesBrenda:2.7.11.1
Brenda:2.7.11.26
DOCK Blaster:1GNG
DOCK Blaster:1H8F
DOCK Blaster:1I09
DOCK Blaster:1J1B
DOCK Blaster:1J1C
DOCK Blaster:1O9U
DOCK Blaster:1PYX
DOCK Blaster:1Q3D
DOCK Blaster:1Q3W
DOCK Blaster:1Q41
DOCK Blaster:1Q4L
DOCK Blaster:1Q5K
DOCK Blaster:1R0E
DOCK Blaster:1UV5
EC:2.7.11.1
EC:2.7.11.26
ENSEMBL:ENSG00000082701
GeneCards:P49841
IntEnz:2.7.11.1
IntEnz:2.7.11.26
KEGG Gene:2932
OMIM:605004
PRO:P49841
Protein Data Bank:1GNG
Protein Data Bank:1H8F
Protein Data Bank:1I09
Protein Data Bank:1J1B
Protein Data Bank:1J1C
Protein Data Bank:1O9U
Protein Data Bank:1PYX
Protein Data Bank:1Q3D
Protein Data Bank:1Q3W
Protein Data Bank:1Q41
Protein Data Bank:1Q4L
Protein Data Bank:1Q5K
Protein Data Bank:1R0E
Protein Data Bank:1UV5
UCSC human:P49841
UniProt:P49841
ZINC_target:P49841
Other identifiers related to this sequenceGSK3B_HUMAN, D3DN89, Q9BWH3, Q9UL47, AAH00251, 40645_at, 3ZDI, HGNC:4617, 1GNG, 2691093, SM00219, 1O6L, 52456_at, 2691022, 4EKK, 3F88, Hs.90063.1.A2_3p_at, 4IQ6, 2691100, IPR001245, 3PUP, EAW79535, 2691096, 4ACD, 242336_at, CH471052, 2691102, 2XH5, 2691046, 2691057, 49465_at, 11754361_s_at, 1J1B, GSK3B-001, 4J1R, ENSG00000082701, 3E8D, 4NM3, 3SD0, 1Q3D, 2691017, 43373_s_at, 1Q5K, 2932, Hs.25777.0.A1_3p_at, 3GB2, 3L1S, 226191_at, 2691015, AAA66475, 2691016, IPR011009, CAG38748, 3OW4, 2691023, 2691106, HPA028017, uc003edo.3, 1R0E, 4J71, A_23_P251342, 209945_s_at, 2JLD, 2OW3, 2O5K, EU302497, Hs.743698, 1253_at, AF098789, 3237612, 2691045, NM_001146156, L33801, 3ZRK, 4DIT, 3ZRM, BAF83586, A_24_P243044, 2691020, 2691061, 2691104, 3DU8, OTTHUMP00000165239, 4ACH, BC012760, 1Q4L, 2691080, 2691095, EAW79536, 2UW9, CAB016263, PF07714, 3E88, Hs.90063.1.A1_3p_at, 4B7T, 1I09, SM00220, 240562_at, 4NM0, 2X39, GE56933, AK290897, L33801_at, g12652980_3p_a_at, GSK3B, 2691021, 4ACC, 2JDO, EAW79534, 3M1S, 3QKK, 1UV5, AAC69340, EAW79533, AF074333, 1H8F, 0007050020, 10486203, 1O9U, 2691018, AAH12760, IPR000719, 16957843, 1Q41, 2691019, 11744456_s_at, Q6FI27, ABX89591, 226183_at, 1J1C, 2691060, IPR002290, 3Q3B, 1O6K, GE57725, 3F7Z, 1Q3W, 4ACG, Hs.614334, 4AFJ, 3CQU, CR536510, 2691031, PH_hs_0038609, MIM:605004, NP_001139628, 3I4B, 3CQW, 2691101, 1PYX, BC000251, CCDS54628, AAD48517, PF00069, 2691111, XP_006713674, ILMN_1779376, 2JDR, 3E87, PH_hs_0023448, 2691059, 3SAY, ENSP00000264235, 2691094, 3ZRL, 8089801, UPI000004DAA4, EntrezGene:2932, 2691036, IPR020635, 2691097, 2691070, OTTHUMP00000165240, NM_002093, 2691039, UPI000002ACBB, uc003edn.3, XP_006713673, GSK3B-002, NP_002084, CCDS2996, ENSP00000324806
Molecules with this sequenceGSK3B [cytosol] UKEOPGPPPPPPPPPPPPPPUDDDDDDDDDDDDDDZ
p-S9-GSK3B [cytosol] UKEOPGPPPPPPPPPPPPPPUDDDDDDDDDDDDDDZ
GSK3B del304-316 [cytosol] UKEOPGPPPPPPPPPPPPPPUDDDDDDDDDDDDDDZ
Component ofAXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
p-S33,S37,T41,S45-beta-catenin:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
p-S33,S37,T41,S45-beta-catenin:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
FRAT1,2:GSK3beta [cytosol]
GSK3B:AXIN1 [cytosol]
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol]
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
CTNNB1 S45 mutants:AXIN:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol]
...
List all 27 items
Represented by generalisation(s)GSK3 [cytosol]
CK1alpha (GSK3) [cytosol]
p-S9/21-GSK3 [cytosol]
Processes where molecules and complexes with this sequence are involved

frog CK1gamma phosphorylates LRP5/6 [Homo sapiens]

Immune System

Signal Transduction

Developmental Biology

Cellular responses to stress

Disease

Modifications in molecules with this sequenceO-phospho-L-serine at 9
Deletion of residues 304 to 316
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