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name	oxidoreductase activity, acting on NADH or NADPH
Accession	GO
Definition	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
Enzyme Classification (EC) number	1.6 1.6
Molecules/complexes with this activity
Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase (name copied from entity in Homo sapiens) [mitochondrial inner membrane] Complex I - NADH:Ubiquinone oxidoreductase [mitochondrial inner membrane] CYB5R3:FAD (name copied from entity in Homo sapiens) [mitochondrial outer membrane] CYB5R3:FAD (name copied from entity in Homo sapiens) [mitochondrial outer membrane] ... List all 61 items
Reactions catalysed by this activity
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Homo sapiens] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Canis familiaris] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Bos taurus] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Sus scrofa] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Mus musculus] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Rattus norvegicus] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Gallus gallus] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Taeniopygia guttata] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Xenopus tropicalis] glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ [Danio rerio] ... List all 63 items
Is a specialisation of activities
oxidoreductase activity GO catalytic activity GO molecular_function GO
Is a generalisation of more specialised activities
oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor GO oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor GO oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO NADH dehydrogenase activity GO oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO