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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P38398
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Breast cancer type 1 susceptibility protein ecNumber6.3.2.-/ecNumber alternativeName: RING finger protein 53
Links to corresponding entries in other databasesBioGPS Gene:672
CTD Gene:672
DOCK Blaster:1JM7
DOCK Blaster:1JNX
DOCK Blaster:1N5O
DOCK Blaster:1OQA
DOCK Blaster:1T15
DOCK Blaster:1T29
DOCK Blaster:1T2U
DOCK Blaster:1T2V
DOCK Blaster:1Y98
ENSEMBL:ENSG00000012048
GeneCards:P38398
HapMap:NM_007294
HapMap:NM_007295
HapMap:NM_007296
KEGG Gene:672
NCBI Gene:672
OMIM:113705
OMIM:114480
Orphanet:15377
PRO:P38398
Protein Data Bank:1JM7
Protein Data Bank:1JNX
Protein Data Bank:1N5O
Protein Data Bank:1OQA
Protein Data Bank:1T15
Protein Data Bank:1T29
Protein Data Bank:1T2U
Protein Data Bank:1T2V
Protein Data Bank:1Y98
RefSeq:NM_007294
RefSeq:NM_007295
RefSeq:NM_007296
RefSeq:NP_009225
RefSeq:NP_009226
RefSeq:NP_009227
RefSeq:NP_009228
UCSC human:P38398
UniProt:P38398
dbSNP Gene:672
Other identifiers related to this sequenceBRCA1_HUMAN, O15129, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9, 3758334, 33724_at, 3758362, DQ190457, ABB87070, 11749632_a_at, IPR011364, g6552300_3p_a_at, DQ299329, 11750373_a_at, HE600032, DQ190452, DQ299312, ABB87074, 3758372, XP_006722094, BAK64160, DQ190454, ABB87063, 1T2V, 1JNX, HE600036, JX480460, DQ299324, AY093487, DQ299305, 3758357, G4V4Z8, 16845349, ABB87079, 1676470, Q3YB53, 11744317_x_at, 3PXD, 3PXE, Q9NQR3, 3758359, ABF14462, ABB87054, DQ145822, Q3LRH8, PH_hs_0044730, 3758371, MIM:614320, 3758324, ENST00000357654, FJ940752, 4IGK, 1OQA, 1T29, AAC00049, PR00493, NM_007294, 3758351, CCDS11453, ILMN_2311089, AAZ16492, E7EWN5, AY093486, 11735584_x_at, BC106745, 3758366, XP_006722099, ABB87056, DQ299306, G1UI37, HPA034966, XM_006722034, DQ299311, CCD57772, CAA70003, XP_006722095, 3758361, ABB87055, K4JXS7, CCD57773, ABA29220, ABB87062, 3758358, AAB61673, BRCA1, DQ190456, 3758318, XM_006722035, DQ299328, AAP12647, 3PXC, AAN61423, DQ190453, SM00184, 3COJ, 3758344, HE600033, AB621825, XP_006722097, HE600037, ACR33809, Hs.622171, AAC37594, K7EPC7, DQ299321, DQ299330, 1Y98, ABB87073, OTTHUMP00000212143, A_23_P207400, L78833, AFU88808, 3758321, 3758375, AAZ79409, ABA29211, L78833_cds1_at, HGNC:1100, 3K15, AAM18222, DQ116737, LRG_292, DQ299315, AY093490, AAC50330, ABB87076, 1T2U, uc002icq.3, G4V500, ABA29217, PF04873, 8015769, 1993_s_at, AY093485, ENSG00000012048, G4V503, g2218153_3p_a_at, DQ299327, Q3YB49, U64805, DQ145826, ABB87057, AFU88804, ABB87069, SM00292, JX480462, Y08757, AAN61425, U64805_s_at, 3758337, XP_006722096, MIM:604370, ABA29214, AAB40910, PH_hs_0011459, AAB08105, 3758319, HE600038, AY093493, 3758360, AAM18223, ABA29208, ENSP00000350283, XM_006722036, 672, PF00533, 3758364, JX480466, 3758341, AAZ79406, ENSP00000420705, 3758368, ABB87072, C4PFY7, Q9UE29, Q3B891, 1T15, U37574, AAM18221, ABB87061, 3758350, LRG_292t1, AAH72418, 3758355, E9PFZ0, K4JUB1, DQ299309, G4V4Z7, U68041, XP_006722093, XM_006722029, MIM:113705, AAI06746, ABB87077, 3PXB, XM_006722032, 3758345, DQ190455, Q92897, AAM18219, Q7KYU6, BC072418, U14680, DQ190450, 204531_s_at, K4K7V3, DQ299326, DQ299322, CCD57774, C9IZW4, AAZ79410, DQ299314, 3K16, GE59309, UPI0000126AC8, AF507076, AY273801, IPR001841, 4IFI, AC135721, PF00097, AAM18226, DQ299331, BRCA1-001, XM_006722033, ABB87075, ABA29223, ABB87053, ABB87071, IPR001357, ABB87078, ABB87058, AF507078, 3758367, XP_006722092, AF005068, 3758335, G4V502, CAB018369, AAA73985, 3758342, CCD57769, AY093489, 604_at, AFU88802, 3758363, ENST00000491747, AAF97939, 1JM7, 3758323, 11755416_x_at, DQ299325, 211851_x_at, DQ299308, ILMN_1738027, AC060780, HE600035, Q3YB50, 0000510746, EntrezGene:672, DQ299310, DQ478408, E7EP70, XM_006722031, 3PXA, 3K0K, AF284812, U61268, Hs.194143, DQ190451, ABA29226, IPR018957, ABA29229, ABB87059, CCD57770, MIM:114480, 2395433, 2ING, 3K0H, XM_006722030, ABB87060, HE600034, Q4EW25, MIM:167000, NP_009225, CAB001946, CCD57768, XP_006722098, DQ145825, DQ299307, 1N5O, DQ299313, AAM18220, CCD57771, DQ299323, UPI000013ECD3, OTTHUMP00000275469, ENSP00000312236, PF11789, BRCA1-029, NM_007299, CCDS11455, OTTHUMP00000212149, BRCA1-007, UPI000037834E, uc002icu.3, NP_009230, ENSP00000417148, GE475511, OTTHUMP00000212152, 69578_at, BRCA1-010, ENSP00000418548, 3758374, 3758316, UPI0000145115, BRCA1-014, XP_006722100, XP_006722102, CCDS11454, UPI000013C85E, AK293762, XP_006722103, NP_009229, uc010whl.2, BAG57181, XP_006722101, OTTHUMP00000212155, B4DES0, NM_007298, BRCA1-020, ENSP00000417988, uc010whs.1, OTTHUMP00000212161
Molecules with this sequenceBRCA1 [nucleoplasm] UKENBCdOOORRRHHHPGPPPPPPPPPURRRRDDDDDDDDD
p-S1189,S1524,S1542-BRCA1 [nucleoplasm] UKENBCdOOORRRHHHPGPPPPPPPPPURRRRDDDDDDDDD
Component ofBRCA1:53BP1 complex at site of DNA double-strand break [nucleoplasm]
BRCA1:BRCA2:PALB2 [nucleoplasm]
Meiotic single-stranded DNA complex [nucleoplasm]
Synaptonemal Complex:BRCA1 [nucleoplasm]
Synaptonemal Complex:BRCA1:ATR [nucleoplasm]
Processes where molecules and complexes with this sequence are involved

Cell Cycle

DNA Repair

Modifications in molecules with this sequenceO-phospho-L-serine at 1189
O-phospho-L-serine at 1542
O-phospho-L-serine at 1524
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