Reactome: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine

N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine [Homo sapiens]

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References
N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine
Stable identifier	REACT_21253.1
Authored	Jupe, S, 2010-02-19
Reviewed	D'Eustachio, P, 2009-12-11
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GPR18 (GPRW) is a receptor for the biologically active anandamide derivative n-arachidonyl glycine.
Input (present at start of reaction)	N-arachidonyl glycine receptor [plasma membrane] U K E G B C d O R R H H U R R N-arachidonyl glycine [extracellular region] C
Output (present at end of reaction)	N-arachidonyl glycine receptor:NAGly [plasma membrane]
Following event(s)	Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi [Homo sapiens]
Organism	Homo sapiens
Cellular compartment	plasma membrane GO
Kohno, M, Hasegawa, H, Inoue, A, Muraoka, M, Miyazaki, T, Oka, K, Yasukawa, M Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18 2006 Biochem Biophys Res Commun PubMed
Participating molecules
N-arachidonyl glycine [extracellular region] C N-arachidonyl glycine receptor [plasma membrane] U K E G B C d O R R H H U R R

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