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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P22455
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Fibroblast growth factor receptor 4 shortName:FGFR-4 ecNumber2.7.10.1/ecNumber cdAntigenNameCD334/cdAntigenName
Links to corresponding entries in other databasesBioGPS Gene:2264
Brenda:2.7.10.1
CTD Gene:2264
DOCK Blaster:1QCT
EC:2.7.10.1
ENSEMBL:ENSG00000160867
GeneCards:P22455
HapMap:NM_002011
HapMap:NM_213647
IntEnz:2.7.10.1
KEGG Gene:2264
NCBI Gene:2264
OMIM:134935
Protein Data Bank:1QCT
RefSeq:NM_002011
RefSeq:NM_213647
RefSeq:NP_002002
RefSeq:NP_998812
UCSC human:P22455
UniProt:P22455
dbSNP Gene:2264
Other identifiers related to this sequenceFGFR4_HUMAN, G3JVM2, G3JVM5, G3JVM7, G3JVM9, O43785, Q14309, Q71TW8, Q8TDA0, Q96KE5, ENSG00000160867, ENST00000393648, ENSP00000377259, ENST00000292408, ENSP00000292408, 1291_s_at, 204579_at, 211237_s_at, 1554962_a_at, 1554961_at, L03840_s_at, g6739817_3p_a_at, g13112051_3p_at, Hs2.165950.4.S1_3p_at, A_14_P131381, A_23_P92754, CCDS4410, CCDS4411, GE57553, X68559, AF359246, AF487555, EF571596, X57205, L03840, Y13901, BC011847, M59373, AF202063, AB209631, EntrezGene:2264, GI_13112049-A, GI_13112051-I, GI_13112049-I, ILMN_29492, IPI00304578, IPI00420109, IPI00556393, MIM:134935, OTTHUMP00000161430, OTTHUMT00000253411, 1QCT, CAB75718, AAK51435, AAM13666, ABQ01235, CAA40490, AAB59389, CAA74200, AAH11847, AAA63208, AAF27432, BAD92868, NM_002011, NM_213647, NM_022963, NP_002002, NP_998812, NP_075252, OTTHUMT00000253410, Hs.165950, Q6LBK2, Q96KE5, Q8TDA0, P22455, Q71TW8, Q59F30, Q6LBK2_HUMAN, Q96KE5_HUMAN, Q8TDA0_HUMAN, FGFR4_HUMAN, Q71TW8_HUMAN, Q59F30_HUMAN, IPR000719, IPR008266, IPR001245, IPR009134, IPR013098, IPR013106, IPR013151, IPR007110
Molecules with this sequenceFGFR4 [plasma membrane] UKENBCdORRHHGURRPD
p-5Y-FGFR4 [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 N535D mutant [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 N535K mutant [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 V550E mutant [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 V550L mutant [plasma membrane] UKENBCdORRHHGURRPD
FGFR4 Y367C mutant [plasma membrane] UKENBCdORRHHGURRPD
phosphorylated FGFR4 Y367C mutant [plasma membrane] UKENBCdORRHHGURRPD
phosphorylated FGFR4 N535K mutant [plasma membrane] UKENBCdORRHHGURRPD
phosphorylated FGFR4 V550E mutant [plasma membrane] UKENBCdORRHHGURRPD
phosphorylated FGFR4 N535D mutant [plasma membrane] UKENBCdORRHHGURRPD
phosphorylated FGFR4 V550L mutant [plasma membrane] UKENBCdORRHHGURRPD
Component ofFGFR4 homodimer [plasma membrane]
FGFR4:HS:KLB:FGF19 [plasma membrane]
Activated FGFR4 homodimer [plasma membrane]
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]
FGFR4 N535D mutant dimer [plasma membrane]
FGFR4 N535K mutant dimer [plasma membrane]
FGFR4 V550E mutant dimer [plasma membrane]
FGFR4 V550L mutant dimer [plasma membrane]
FGFR4 Y367C mutant dimer [plasma membrane]
Activated FGFR4 Y367C mutant [plasma membrane]
...
List all 46 items
Represented by generalisation(s)FGFR4 enhanced kinase mutants [plasma membrane]
Processes where molecules and complexes with this sequence are involved

Immune System

Signal Transduction

Disease

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 643
O4'-phospho-L-tyrosine at 719
O4'-phospho-L-tyrosine at 642
O4'-phospho-L-tyrosine at 754
O4'-phospho-L-tyrosine at 764
L-asparagine 535 replaced with L-aspartic acid
L-asparagine 535 replaced with L-lysine
L-valine 550 replaced with L-glutamic acid
L-valine 550 replaced with L-leucine
L-tyrosine 367 replaced with L-cysteine
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