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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P22455
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Fibroblast growth factor receptor 4 shortName:FGFR-4 ecNumber2.7.10.1/ecNumber cdAntigenNameCD334/cdAntigenName
Links to corresponding entries in other databasesBioGPS Gene:2264
Brenda:2.7.10.1
CTD Gene:2264
DOCK Blaster:1QCT
EC:2.7.10.1
ENSEMBL:ENSG00000160867
GeneCards:P22455
HapMap:NM_002011
HapMap:NM_213647
IntEnz:2.7.10.1
KEGG Gene:2264
NCBI Gene:2264
OMIM:134935
PRO:P22455
Protein Data Bank:1QCT
RefSeq:NM_002011
RefSeq:NM_213647
RefSeq:NP_002002
RefSeq:NP_998812
UCSC human:P22455
UniProt:P22455
ZINC_target:P22455
dbSNP Gene:2264
Other identifiers related to this sequenceFGFR4_HUMAN, G3JVM2, G3JVM5, G3JVM7, G3JVM9, O43785, Q14309, Q71TW8, Q8TDA0, Q96KE5, JN007480, 211237_s_at, AEO19712, NP_998812, XP_005265895, SM00408, ILMN_1730355, SM00219, XM_005265837, 2842932, AEO19714, NM_002011, 2842936, IPR001245, D6R9V0, CH471195, 8110265, AF487555, 2842918, 2842915, IPR013098, CAA40490, JN007473, NP_002002, 2842930, AEO19718, 2842939, JN007474, 11735873_a_at, 0005290176, 11752172_a_at, AEO19723, D6RJD4, FGFR4, MIM:134935, PF07679, IPR011009, ENSP00000292408, A_14_P131381, 2842933, HPA027273, FGFR4-001, IPR007110, AEO19721, JN007477, 2264, IPR003598, L03840, XM_005265838, ABQ01235, AAH11847, XP_005265894, JN007478, 2842943, 2842922, AAK51435, 11740240_a_at, CAB005196, 2842913, AF359246, 2842935, g13112051_3p_at, A_23_P92754, JN007482, AEO19715, 2842941, E7EWF4, HPA027369, AAM13666, JN007475, PR00109, 204579_at, ILMN_2410713, AF202063, 2842926, SM00409, 1QCT, AEO19717, JN007481, PF07714, AAB59389, Y13901, AEO19716, AEO19719, AAF27432, JN007479, 0001090372, SM00220, OTTHUMP00000161429, 2842912, 1554962_a_at, 2842920, M59373, 2842938, AEO19713, g6739817_3p_a_at, PF00047, 2842916, JN007471, HPA028251, IPR000719, PH_hs_0010000, HGNC:3691, 2842928, 11757181_x_at, 2842924, AEO19722, UPI000012A72D, 2842944, IPR002290, IPR016248, GE57553, L03840_s_at, 16992957, AC027314, CAA74200, IPR003599, uc003mfm.3, ENSG00000160867, AAA63208, EAW85036, AEO19720, CCDS4410, BC011847, JN007472, 2842923, PF00069, JN007476, 1291_s_at, EntrezGene:2264, 2842934, NM_213647, 11753528_a_at, X57205, 11744657_x_at, 2842914, EF571596, D6RG06, IPR020635, IPR013151, uc003mfl.3, FGFR4-004, ENSP00000424960, OTTHUMP00000223541, NM_022963, NP_075252, FGFR4-002, 2842931, uc003mfo.3, ENSP00000377254, OTTHUMP00000161430, 0000110440, UPI000013E0B8, CCDS4411, ILMN_2241412
Molecules with this sequenceFGFR4 [plasma membrane] UKENBCdORRHHPGPURRDZ
p-5Y-FGFR4 [plasma membrane] UKENBCdORRHHPGPURRDZ
FGFR4 N535D mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
FGFR4 N535K mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
FGFR4 V550E mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
FGFR4 V550L mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
FGFR4 Y367C mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
phosphorylated FGFR4 Y367C mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
phosphorylated FGFR4 N535K mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
phosphorylated FGFR4 V550E mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
phosphorylated FGFR4 N535D mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
phosphorylated FGFR4 V550L mutant [plasma membrane] UKENBCdORRHHPGPURRDZ
Component ofFGFR4 homodimer [plasma membrane]
FGFR4:HS:KLB:FGF19 [plasma membrane]
Activated FGFR4 homodimer [plasma membrane]
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]
FGFR4 N535D mutant dimer [plasma membrane]
FGFR4 N535K mutant dimer [plasma membrane]
FGFR4 V550E mutant dimer [plasma membrane]
FGFR4 V550L mutant dimer [plasma membrane]
FGFR4 Y367C mutant dimer [plasma membrane]
Activated FGFR4 Y367C mutant [plasma membrane]
...
List all 46 items
Represented by generalisation(s)FGFR4 enhanced kinase mutants [plasma membrane]
Processes where molecules and complexes with this sequence are involved

Immune System

Signal Transduction

Disease

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 643
O4'-phospho-L-tyrosine at 719
O4'-phospho-L-tyrosine at 642
O4'-phospho-L-tyrosine at 754
O4'-phospho-L-tyrosine at 764
L-asparagine 535 replaced with L-aspartic acid
L-asparagine 535 replaced with L-lysine
L-valine 550 replaced with L-glutamic acid
L-valine 550 replaced with L-leucine
L-tyrosine 367 replaced with L-cysteine
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