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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P13760
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: HLA class II histocompatibility antigen, DRB1-4 beta chain alternativeName: MHC class II antigen DRB1*4 shortName:DR-4 shortName:DR4
Links to corresponding entries in other databasesBioGPS Gene:3123
CTD Gene:3123
DOCK Blaster:1AQD
DOCK Blaster:1BX2
DOCK Blaster:1D5M
DOCK Blaster:1D5X
DOCK Blaster:1D5Z
DOCK Blaster:1D6E
DOCK Blaster:1DLH
DOCK Blaster:1FYT
DOCK Blaster:1J8H
DOCK Blaster:1JWM
DOCK Blaster:1JWS
DOCK Blaster:1JWU
DOCK Blaster:1KG0
DOCK Blaster:1KLG
DOCK Blaster:1KLU
DOCK Blaster:1LO5
DOCK Blaster:1SEB
DOCK Blaster:1SJE
DOCK Blaster:1SJH
DOCK Blaster:1T5W
DOCK Blaster:1T5X
DOCK Blaster:1YMM
DOCK Blaster:2SEB
ENSEMBL:ENSG00000196126
GeneCards:P13760
HapMap:NM_002124
NCBI Gene:3123
OMIM:142857
OMIM:181000
Protein Data Bank:1AQD
Protein Data Bank:1BX2
Protein Data Bank:1D5M
Protein Data Bank:1D5X
Protein Data Bank:1D5Z
Protein Data Bank:1D6E
Protein Data Bank:1DLH
Protein Data Bank:1FYT
Protein Data Bank:1J8H
Protein Data Bank:1JWM
Protein Data Bank:1JWS
Protein Data Bank:1JWU
Protein Data Bank:1KG0
Protein Data Bank:1KLG
Protein Data Bank:1KLU
Protein Data Bank:1LO5
Protein Data Bank:1SEB
Protein Data Bank:1SJE
Protein Data Bank:1SJH
Protein Data Bank:1T5W
Protein Data Bank:1T5X
Protein Data Bank:1YMM
Protein Data Bank:2SEB
RefSeq:NM_002124
RefSeq:NP_002115
UCSC human:P13760
UniProt:P13760
dbSNP Gene:3123
Other identifiers related to this sequence2B14_HUMAN, O19717, O19739, P13759, Q29875, Q30145, Q9GIX9, Q9GIY4, Q9MY13, Q9XRY5, ENSG00000196126, ENST00000360004, ENSP00000353099, 215193_x_at, 209312_x_at, 238900_at, 54906_r_at, 63416_s_at, 66780_at, 75284_f_at, M33600_f_at, Hs.279930.1.S1_3p_x_at, Hs.194490.0.S1_3p_x_at, Hs.194490.0.S1_3p_s_at, g5478215_3p_x_at, 238900_3p_at, Hs.194490.0.S1_3p_at, Hs.279930.0.S2_3p_s_at, A_23_P31006, A_24_P343233, AM412363, EF156366, BX296568, AF092562, U84892, U08932, U26558, U45999, L23963, M28584, DQ021904, AY961074, AY766103, AJ508388, AJ539471, AY174180, AY042678, AF029291, AF029290, AF029275, AF029270, AF029267, EF078988, AY604574, AF010142, M81170, AJ223124, AF093411, U08274, U25638, M16957, X65031, X12544, M28583, DQ284435, M30180, M94460, M63337, M35651, AM110006, DQ002917, AY663414, AJ536121, AJ507382, AJ507425, U56640, AF029292, AF029281, X64436, AY604576, AY604578, AJ001253, L26306, DQ525631, L14852, M64794, L27216, DQ192647, AY912074, AM110004, AM109970, AY663409, AY663393, AY179370, AJ421519, U58978, AF029289, AF029274, AF235034, AF239244, AF190132, AF142467, AY604573, AY604575, AF028590, X64546, U38974, X74343, L34025, M63338, M20504, AM110005, DQ133167, AY961073, AY331806, AF489519, AF363727, AF373015, AF335231, AJ297503, AF029280, AF029268, AF242355, AJ238410, X69599, AM419948, AF011786, M13278, M81172, DQ837166, DQ514603, U08276, U41489, M16959, AM040719, M30179, U59686, D14352, AM056024, AY947537, AY225130, AJ506752, AF436097, AF297459, AF172070, AM409257, EF078985, Y15404, D49823, U25442, AM258966, U08277, DQ284432, L27217, DQ179043, DQ097864, AY663400, AY429729, AY283603, AY304505, AJ507782, AJ431718, AF349316, AF304866, AJ293861, AF029273, AF029272, AJ245881, AY604572, AY604577, M81176, DQ525632, U25639, U38520, M16958, M15068, M17378, DQ179036, DQ130065, AY961075, AY714542, AY626552, AY374099, M35002, AY122288, AJ297705, AF243536, AF029271, AF191104, AF101127, X64437, AB007634, AF017440, U03721, U26659, DQ525633, DQ514601, L02545, BC108922, DQ185603, DQ179040, AY663404, AY525097, AY428805, AB176445, AB106127, AF439712, AF029282, AF142469, AF142468, AF142461, AL713966, M20430, BC033827, AY663406, AY663395, AY663411, AY961072, AY961063, AJ556173, BC024269, AY961062, AF291675, AY961068, M11161, X03069, X64547, AF029288, AF029293, M21008, Z50871, M33600, X99896, AB015184, AF089723, AJ303118, AJ276206, M20548, M20549, M20550, AL137064, M17381, K02776, X96851, AJ297586, AF029269, AF112876, AJ295845, X02902, M15069, L42143, EntrezGene:3123, GI_4504410-S, ILMN_18172, ILMN_20550, IPI00010397, IPI00472169, IPI00738107, MIM:142857, MIM:181000, OTTHUMT00000076393, 1YMM, 1J8H, 1AQD, 1BX2, 1DLH, 1FYT, 1JWM, 1JWS, 1JWU, 1KG0, 1KLG, 1KLU, 1LO5, 1SEB, 1SJE, 1SJH, 1T5W, 1T5X, 1D5M, 1D5X, 1D5Z, 1D6E, 2SEB, CAL85404, ABL98033, AAD03597, AAB42072, AAA21276, AAA67957, AAA87226, AAA67123, AAA59681, AAY43234, AAX63462, AAW47394, CAD48196, CAD62435, AAO17052, AAK94509, AAF65500, AAF65499, AAF65485, AAF65480, AAF65477, ABK56698, AAV33675, AAB81176, AAA91837, CAA11127, AAD10735, AAB87709, AAB02172, AAA36279, CAA46165, CAA31061, AAA59680, ABC66201, AAA59714, AAA59779, AAC41708, AAA59806, CAJ33613, AAY21682, AAU88033, CAD60087, CAD45639, CAD45638, AAC02715, AAF65501, AAF65490, CAL69438, AAV33677, AAV33679, CAA04627, AAA67471, ABF74596, AAC37561, AAA36273, AAA59789, ABA39176, AAY17287, CAJ33611, CAJ33577, AAU88018, AAO23241, CAD13439, AAB07001, AAF65498, AAF65484, AAF73947, AAF59946, AAF08286, AAD31311, AAV33674, AAV33676, AAB84140, CAA45844, AAA81369, CAA52390, AAA74994, AAC41709, AAA59827, CAJ33612, AAZ41843, AAX63461, AAU87974, AAP93590, AAL92173, AAK51524, AAK54252, AAK20873, CAC27124, AAF65489, AAF65478, AAF82750, CAB42824, CAL69446, CAL99240, AAB65751, AAA59798, AAA91839, ABH05946, ABF60566, AAB06832, AAA86242, AAA36281, CAJ13641, AAA59842, AAB52230, BAA03281, CAJ20745, AAX47961, AAO67518, CAD44945, AAL30416, AAG17449, AAD51969, CAL64839, ABK56695, CAA75604, BAA08628, AAB50934, CAJ90451, AAB06831, ABC66199, AAA99889, ABA06601, AAZ43252, AAU87993, AAR10883, AAQ18119, AAP76509, CAD47818, CAD24479, AAK30584, AAG22827, CAC05373, AAF65483, AAF65482, CAB75359, AAV33673, AAV33678, CAM25995, AAA91843, ABF74597, AAB02173, AAA96820, AAA36280, AAA59811, AAA59801, ABA06594, AAZ42160, AAX63463, AAW57989, AAV41230, AAR21104, AAA53102, AAM88570, CAC10354, AAG00413, AAF65481, AAF03162, AAD16437, CAL69439, BAA22609, AAB70554, AAA03486, AAD09441, ABF74598, ABF60564, AAA59777, AAI08923, ABA28306, ABA06598, AAU88003, AAS19443, AAR07616, BAD15071, BAC66086, AAL35224, AAF65491, AAD31313, AAD31312, AAD31305, AAA59831, AAH33827, AAU88008, CAI18081, AAU87979, AAU88023, AAX63460, AAX63451, CAD89003, AAH24269, AAX63450, AAK91825, AAX63456, AAA59781, CAA26873, CAA45845, AAF65497, AAF65502, AAA59780, AAA59782, CAA68171, BAA28761, AAD51131, CAC19693, CAC27123, CAC19360, AAA59805, AAA59808, CAC08826, AAF65479, AAD29581, CAC08181, CAA26660, AAA59809, AAA67104, NM_002124, NP_002115, A0PFV9, A1Z0K9, O98046, P79552, Q29650, Q29691, Q29744, Q29830, Q29975, Q4U0U6, Q56FN8, Q5ID26, Q860S0, Q861A5, Q861H6, Q95IE6, Q9MXZ2, Q9MXZ3, Q9MY07, Q9MY12, Q9MY15, A0N0W3, A1A415, O19517, O19731, O78044, O98047, Q29646, Q29687, Q29790, Q29888, Q29890, Q29974, Q2LIR3, Q30008, Q30123, Q30157, Q31624, Q3LA84, Q4ZJJ2, Q5Y7B0, Q860C0, Q860S1, Q860S2, Q95379, Q9MXZ1, Q9MY02, A0N998, A1A417, A1A419, O78048, Q15442, Q19K84, Q29786, Q30122, Q30128, Q3HUP9, Q3KTM1, Q3LA86, Q3LAC0, Q5Y7C5, Q861G2, Q8WLR9, Q95381, Q9MXZ4, Q9MY08, Q9MYA1, Q9MYD9, Q9TP94, Q9TQ40, A1A414, A1A416, O19594, Q06653, Q29728, Q29834, Q30130, Q30156, Q30159, Q3LA85, Q45G75, Q56FN9, Q5Y7G9, Q7YP63, Q8SNC3, Q95HN3, Q95IG7, Q9BCS7, Q9BD10, Q9MY03, Q9MY14, Q9MYA0, Q9Y454, A0N9E1, A4F5N0, O19518, O19729, O19732, Q0PGR5, Q1G0Z8, Q29648, Q29734, Q29792, Q2PBC3, Q30179, Q30200, Q31645, Q4A1G9, Q58HT8, Q860T0, Q861B8, Q95HL8, Q9GJ37, Q9TPW2, A0AQZ0, A0N0W0, O19786, P79494, Q29686, Q1JRP4, Q29649, Q2LIR5, Q30129, Q3LTJ1, Q45W57, Q5Y7E9, Q6T713, Q6WIG7, Q7YPW3, Q8HWN3, Q8MGY6, Q9BCQ0, Q9GJ28, Q9GJE9, Q9MY09, Q9MY10, Q9MYB9, A1A413, A1A418, A2BFX2, O19734, Q19K83, Q29688, Q29727, Q29791, Q30103, Q30142, Q3LTJ8, Q45KF7, Q56FN7, Q5DKQ6, Q5IWM0, Q6UB42, Q7JFU9, Q8MGZ7, Q9GIX7, Q9GJG1, Q9MY11, Q9TP93, Q9TQ83, A0N999, O19502, O19586, O19621, O98212, Q19K82, Q1G100, Q30120, Q32MY7, Q3LRY0, Q3LTJ4, Q5Y7E0, Q6QUQ1, Q6T865, Q75NJ4, Q860S9, Q8WMA1, Q9MY01, Q9TQ38, Q9TQ39, Q9TQ46, Q30166, Q5Y7B9, Q70Q10, Q8TB62, Q95IH1, P04229, P13760, P01911, A0PFV9_HUMAN, A1Z0K9_HUMAN, O98046_HUMAN, P79552_HUMAN, Q29650_HUMAN, Q29691_HUMAN, Q29744_HUMAN, Q29830_HUMAN, Q29975_HUMAN, Q4U0U6_HUMAN, Q56FN8_HUMAN, Q5ID26_HUMAN, Q860S0_HUMAN, Q861A5_HUMAN, Q861H6_HUMAN, Q95IE6_HUMAN, Q9MXZ2_HUMAN, Q9MXZ3_HUMAN, Q9MY07_HUMAN, Q9MY12_HUMAN, Q9MY15_HUMAN, A0N0W3_HUMAN, A1A415_HUMAN, O19517_HUMAN, O19731_HUMAN, O78044_HUMAN, O98047_HUMAN, Q29646_HUMAN, Q29687_HUMAN, Q29790_HUMAN, Q29888_HUMAN, Q29890_HUMAN, Q29974_HUMAN, Q2LIR3_HUMAN, Q30008_HUMAN, Q30123_HUMAN, Q30157_HUMAN, Q31624_HUMAN, Q3LA84_HUMAN, Q4ZJJ2_HUMAN, Q5Y7B0_HUMAN, Q860C0_HUMAN, Q860S1_HUMAN, Q860S2_HUMAN, Q95379_HUMAN, Q9MXZ1_HUMAN, Q9MY02_HUMAN, A0N998_HUMAN, A1A417_HUMAN, A1A419_HUMAN, O78048_HUMAN, Q15442_HUMAN, Q19K84_HUMAN, Q29786_HUMAN, Q30122_HUMAN, Q30128_HUMAN, Q3HUP9_HUMAN, Q3KTM1_HUMAN, Q3LA86_HUMAN, Q3LAC0_HUMAN, Q5Y7C5_HUMAN, Q861G2_HUMAN, Q8WLR9_HUMAN, Q95381_HUMAN, Q9MXZ4_HUMAN, Q9MY08_HUMAN, Q9MYA1_HUMAN, Q9MYD9_HUMAN, Q9TP94_HUMAN, Q9TQ40_HUMAN, A1A414_HUMAN, A1A416_HUMAN, O19594_HUMAN, Q06653_HUMAN, Q29728_HUMAN, Q29834_HUMAN, Q30130_HUMAN, Q30156_HUMAN, Q30159_HUMAN, Q3LA85_HUMAN, Q45G75_HUMAN, Q56FN9_HUMAN, Q5Y7G9_HUMAN, Q7YP63_HUMAN, Q8SNC3_HUMAN, Q95HN3_HUMAN, Q95IG7_HUMAN, Q9BCS7_HUMAN, Q9BD10_HUMAN, Q9MY03_HUMAN, Q9MY14_HUMAN, Q9MYA0_HUMAN, Q9Y454_HUMAN, A0N9E1_HUMAN, A4F5N0_HUMAN, O19518_HUMAN, O19729_HUMAN, O19732_HUMAN, Q0PGR5_HUMAN, Q1G0Z8_HUMAN, Q29648_HUMAN, Q29734_HUMAN, Q29792_HUMAN, Q2PBC3_HUMAN, Q30179_HUMAN, Q30200_HUMAN, Q31645_HUMAN, Q4A1G9_HUMAN, Q58HT8_HUMAN, Q860T0_HUMAN, Q861B8_HUMAN, Q95HL8_HUMAN, Q9GJ37_HUMAN, Q9TPW2_HUMAN, A0AQZ0_HUMAN, A0N0W0_HUMAN, O19786_HUMAN, P79494_HUMAN, Q29686_HUMAN, Q1JRP4_HUMAN, Q29649_HUMAN, Q2LIR5_HUMAN, Q30129_HUMAN, Q3LTJ1_HUMAN, Q45W57_HUMAN, Q5Y7E9_HUMAN, Q6T713_HUMAN, Q6WIG7_HUMAN, Q7YPW3_HUMAN, Q8HWN3_HUMAN, Q8MGY6_HUMAN, Q9BCQ0_HUMAN, Q9GJ28_HUMAN, Q9GJE9_HUMAN, Q9MY09_HUMAN, Q9MY10_HUMAN, Q9MYB9_HUMAN, A1A413_HUMAN, A1A418_HUMAN, A2BFX2_HUMAN, O19734_HUMAN, Q19K83_HUMAN, Q29688_HUMAN, Q29727_HUMAN, Q29791_HUMAN, Q30103_HUMAN, Q30142_HUMAN, Q3LTJ8_HUMAN, Q45KF7_HUMAN, Q56FN7_HUMAN, Q5DKQ6_HUMAN, Q5IWM0_HUMAN, Q6UB42_HUMAN, Q7JFU9_HUMAN, Q8MGZ7_HUMAN, Q9GIX7_HUMAN, Q9GJG1_HUMAN, Q9MY11_HUMAN, Q9TP93_HUMAN, Q9TQ83_HUMAN, A0N999_HUMAN, O19502_HUMAN, O19586_HUMAN, O19621_HUMAN, O98212_HUMAN, Q19K82_HUMAN, Q1G100_HUMAN, Q30120_HUMAN, Q32MY7_HUMAN, Q3LRY0_HUMAN, Q3LTJ4_HUMAN, Q5Y7E0_HUMAN, Q6QUQ1_HUMAN, Q6T865_HUMAN, Q75NJ4_HUMAN, Q860S9_HUMAN, Q8WMA1_HUMAN, Q9MY01_HUMAN, Q9TQ38_HUMAN, Q9TQ39_HUMAN, Q9TQ46_HUMAN, Q30166_HUMAN, Q5Y7B9_HUMAN, Q70Q10_HUMAN, Q8TB62_HUMAN, Q95IH1_HUMAN, 2B11_HUMAN, 2B14_HUMAN, HB2G_HUMAN, IPR003006, IPR000353, IPR003597, IPR013151, IPR007110
Molecules with this sequenceHLA class II histocompatibility antigen, DRB1-4 beta chain [plasma membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [trans-Golgi network membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [endocytic vesicle membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [lysosomal membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [integral component of lumenal side of endoplasmic reticulum membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [transport vesicle membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [ER to Golgi transport vesicle membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [clathrin-coated endocytic vesicle membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
HLA class II histocompatibility antigen, DRB1-4 beta chain [Golgi membrane] UENBCdOORHGURPPPPPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDDDDDD
Component ofMHC class II alpha/beta dimer [plasma membrane]
MHC II alpha/beta dimer [trans-Golgi network membrane]
MHC class II alpha/beta dimer [endocytic vesicle membrane]
MHC II alpha/beta dimer [lysosomal membrane]
MHC II alpha beta heterodimer [integral component of lumenal side of endoplasmic reticulum membrane]
MHC class II alpha/beta/Ii nonamer [transport vesicle membrane]
MHC II alpha/beta dimer [ER to Golgi transport vesicle membrane]
MHC class II alpha/beta dimer [clathrin-coated endocytic vesicle membrane]
MHC II alpha/beta dimer [Golgi membrane]
MHC Class II bearing antigen peptide [plasma membrane]
...
List all 38 items
Represented by generalisation(s)HLA II beta chain [plasma membrane]
HLA II beta chain [trans-Golgi network membrane]
HLA II beta chain [endocytic vesicle membrane]
HLA II beta chain [lysosomal membrane]
HLA II beta chain [integral component of lumenal side of endoplasmic reticulum membrane]
HLA II beta chain [transport vesicle membrane]
HLA II beta chain [ER to Golgi transport vesicle membrane]
HLA II beta chain [clathrin-coated endocytic vesicle membrane]
HLA II beta chain [Golgi membrane]
Processes where molecules and complexes with this sequence are involved

Immune System

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