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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:O75874
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Isocitrate dehydrogenase [NADP] cytoplasmic shortName:IDH ecNumber1.1.1.42/ecNumber alternativeName: Cytosolic NADP-isocitrate dehydrogenase alternativeName: IDP alternativeName: NADP(+)-specific ICDH alternativeName: Oxalosuccinate decarboxylase
Links to corresponding entries in other databasesBioGPS Gene:3417
Brenda:1.1.1.42
CTD Gene:3417
DOCK Blaster:1T09
DOCK Blaster:1T0L
EC:1.1.1.42
ENSEMBL:ENSG00000138413
GeneCards:O75874
HapMap:NM_005896
IntEnz:1.1.1.42
KEGG Gene:3417
NCBI Gene:3417
OMIM:147700
Protein Data Bank:1T09
Protein Data Bank:1T0L
RefSeq:NM_005896
RefSeq:NP_005887
UCSC human:O75874
UniProt:O75874
dbSNP Gene:3417
Other identifiers related to this sequenceIDHC_HUMAN, Q567U4, Q6FHQ6, Q7Z3V0, Q93090, Q9NTJ9, Q9UKW8, ENSG00000138413, ENST00000345146, ENSP00000260985, 201193_at, 1555037_a_at, 39023_at, 64372_r_at, U62389_at, g5174470_3p_x_at, g5174470_3p_at, Hs2.11223.2.S1_3p_s_at, A_32_P45009, A_23_P5376, A_32_P180617, CCDS2381, GE54157, AC016697, CR536499, CR533522, DQ403082, BX537411, BC093020, CR541695, AF020038, AF113917, AL136702, BC012846, U62389, EntrezGene:3417, GI_28178824-S, ILMN_14217, IPI00027223, MIM:147700, 1T09, 1T0L, CAG38738, CAG38553, ABD77215, CAD97653, AAH93020, AAX93221, CAG46496, AAD02918, AAD29284, CAB66637, AAH12846, AAB17375, NM_005896, XR_018565, XR_016519, NP_005887, OTTHUMT00000256475, Hs.593422, Hs.646711, Hs.698327, Q6FI37, Q6FIA4, Q0QER2, Q7Z3V0, Q567U4, Q6FHQ6, O75874, Q6FI37_HUMAN, Q6FIA4_HUMAN, Q0QER2_HUMAN, Q7Z3V0_HUMAN, Q567U4_HUMAN, Q6FHQ6_HUMAN, IDHC_HUMAN, IPR001804
Molecules with this sequenceIDH1 [peroxisomal matrix] UKENBCdORHGURPPDD
IDH1 [cytosol] UKENBCdORHGURPPDD
IDH1 R132L mutant [cytosol] UKENBCdORHGURPPDD
IDH1 R132H mutant [cytosol] UKENBCdORHGURPPDD
IDH1 R132C mutant [cytosol] UKENBCdORHGURPPDD
IDH1 R132S mutant [cytosol] UKENBCdORHGURPPDD
Component ofIDH1 dimer [cytosol]
IDH1 dimer [peroxisomal matrix]
IDH1 R132C dimer [cytosol]
IDH1 R132H dimer [cytosol]
IDH1 R132L dimer [cytosol]
IDH1 R132S dimer [cytosol]
Processes where molecules and complexes with this sequence are involved

Metabolism

Disease

Modifications in molecules with this sequenceL-arginine 132 replaced with L-serine
L-arginine 132 replaced with L-leucine
L-arginine 132 replaced with L-histidine
L-arginine 132 replaced with L-cysteine
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