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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P25963
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: NF-kappa-B inhibitor alpha alternativeName: I-kappa-B-alpha shortName:IkB-alpha shortName:IkappaBalpha alternativeName: Major histocompatibility complex enhancer-binding protein MAD3
Links to corresponding entries in other databasesBioGPS Gene:4792
CTD Gene:4792
DOCK Blaster:1IKN
DOCK Blaster:1NFI
ENSEMBL:ENSG00000100906
GeneCards:P25963
HapMap:NM_020529
KEGG Gene:4792
NCBI Gene:4792
OMIM:164008
Orphanet:17400
PRO:P25963
Protein Data Bank:1IKN
Protein Data Bank:1NFI
RefSeq:NM_020529
RefSeq:NP_065390
UCSC human:P25963
UniProt:P25963
ZINC_target:P25963
dbSNP Gene:4792
Other identifiers related to this sequenceIKBA_HUMAN, B2R8L6, AAH04983, NFKBIA, AAP35754, 3561044, PH_hs_0004662, ENSG00000100906, A_23_P106002, 1NFI, LRG_89t1, 11757894_x_at, NP_065390, NFKBIA-001, HPA029207, EAW65875, AK313421, AAR29599, IPR020683, ENSP00000216797, GE82547, 3561050, 11745878_x_at, Q9UGJ5, BAG36213, AJ249284, M69043_at, BC002601, PF00023, OTTHUMP00000178842, UPI000004F0A9, CH471078, uc001wtf.4, 16791991, LRG_89, BC004983, AJ249285, CAB65113, 3561046, 1IKN, 7978644, SM00248, PR01415, IKBA, AJ249294, ENST00000216797, G3V286, 201502_s_at, IPR002110, NM_020529, EntrezGene:4792, 3561040, ILMN_1773154, MIM:612132, AAK51149, AL133163, Hs.81328.0.S1_3p_a_at, AJ249295, M69043, CCDS9656, CAB003815, MIM:164008, 0001050280, BT007091, AJ249286, AY033600, 3561054, 11744000_a_at, AAA16489, 3561053, AJ249290, AJ249283, 3561041, HGNC:7797, 1461_at, CAB65556, 4792, 3561043, 3561048, AAH02601, 1829648, AY496422
Molecules with this sequenceNFKBIA [cytosol] UKENBCdOORHPGPPURDDZ
p-S32,S36-NFKBIA [cytosol] UKENBCdOORHPGPPURDDZ
Ub-21,22-p-S32,S36-NFKBIA [cytosol] UKENBCdOORHPGPPURDDZ
Component ofIkB(alpha):NF-kB complex [cytosol]
NF-KappaB p50:p50:IKBA [cytosol]
Ubiquitinated phospho-IkB [cytosol]
NF-KappaB p50:p50:p-IKBA [cytosol]
p-S32,36-IkB-alpha:NF-kB complex [cytosol]
NF-KappaB p50:p50:ub-p-IKBA [cytosol]
IkBs:NFkB [cytosol]
NF-kappaB p50:c-Rel:IkB [cytosol]
NF-kappaB p50:p65:IKB [cytosol]
NF-kappaB p65:p65:IKB [cytosol]
...
List all 16 items
Represented by generalisation(s)NF-kappaB inhibitor [cytosol]
IKB alpha,beta,epsilon [cytosol]
Phospho-NF-kappaB Inhibitor [cytosol]
p-IKB alpha,beta,epsilon [cytosol]
ub-p-IKB alpha,beta,epsilon [cytosol]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Immune System

TRAF6 Mediated Induction of proinflammatory cytokines

Modifications in molecules with this sequenceO-phospho-L-serine at 32
O-phospho-L-serine at 32
O-phospho-L-serine at 36
ubiquitinylated lysine at 21
ubiquitinylated lysine at 22
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