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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P06213
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Insulin receptor shortName:IR ecNumber2.7.10.1/ecNumber cdAntigenNameCD220/cdAntigenName component recommendedName: Insulin receptor subunit alpha /component component recommendedName: Insulin receptor subunit beta /component
Links to corresponding entries in other databasesBioGPS Gene:3643
Brenda:2.7.10.1
CTD Gene:3643
DOCK Blaster:1GAG
DOCK Blaster:1I44
DOCK Blaster:1IR3
DOCK Blaster:1IRK
DOCK Blaster:1P14
DOCK Blaster:1RQQ
DOCK Blaster:2AUH
DOCK Blaster:2B4S
EC:2.7.10.1
ENSEMBL:ENSG00000171105
GeneCards:P06213
HapMap:NM_000208
IntEnz:2.7.10.1
KEGG Gene:3643
NCBI Gene:3643
OMIM:125853
OMIM:147670
OMIM:246200
OMIM:262190
OMIM:609968
OMIM:610549
Protein Data Bank:1GAG
Protein Data Bank:1I44
Protein Data Bank:1IR3
Protein Data Bank:1IRK
Protein Data Bank:1P14
Protein Data Bank:1RQQ
Protein Data Bank:2AUH
Protein Data Bank:2B4S
RefSeq:NM_000208
RefSeq:NP_000199
UCSC human:P06213
UniProt:P06213
dbSNP Gene:3643
Other identifiers related to this sequenceINSR_HUMAN, Q17RW0, Q59H98, Q9UCB7, Q9UCB8, Q9UCB9, ENSG00000171105, ENST00000302850, ENSP00000303830, 1572_s_at, 213792_s_at, 207851_s_at, 226212_s_at, 226450_at, 226216_at, 227432_s_at, 33162_at, 47628_at, 65110_at, 70604_at, M10051_s_at, X02160_at, Hs.89695.1.A1_3p_at, g4557883_3p_a_at, Hs.208334.0.S1_3p_at, Hs.98401.0.S1_3p_at, Hs.208334.0.S2_3p_s_at, Hs.89695.2.A1_3p_at, A_14_P119488, A_14_P137289, A_14_P118054, A_14_P123206, A_24_P693768, A_32_P149735, A_23_P4764, A_32_P27041, CCDS12176, GE59638, DQ333193, DQ311690, DQ333195, DQ311689, DQ021481, DQ333194, BC047591, DQ311687, DQ333190, DQ333196, EF207604, DQ333191, DQ333192, EF207610, EF207605, EF207606, EF207607, EF207609, EF207612, EF207608, EF207611, M10051, X02160, M32972, M23100, M32823, M32824, M32825, M32826, M32827, M32828, M32829, M32830, M32831, M32832, M32833, M32834, M32835, M32836, M32837, M32838, M32839, M32840, M32841, M32842, J03466, J05043, M76592, M24555, M29929, M29930, M27197, M27195, BC117172, AB208861, EntrezGene:3643, GI_4557883-S, ILMN_18882, IPI00025803, IPI00794155, IPI00220325, IPI00783573, MIM:147670, MIM:125853, MIM:246200, MIM:262190, MIM:609968, MIM:610549, 2AUH, 1GAG, 1I44, 1IR3, 1IRK, 1P14, 1RQQ, 2B4S, ABC46550, ABC55362, ABC46552, ABC55361, AAY44085, ABC46551, AAH47591, ABC55359, ABC46547, ABC46553, ABP68900, ABC46548, ABC46549, ABP68906, ABP68901, ABP68902, ABP68903, ABP68905, ABP68907, ABP68904, ABP73389, AAA59174, CAA26096, AAA59452, AAA59175, AAA59190, AAC37604, AAA59178, AAA59176, AAA59177, AAA86791, AAI17173, BAD92098, NM_000208, NM_001079817, NP_000199, NP_001073285, Hs.465744, Hs.693974, Hs.694195, Q2PJC4, Q2MKN9, Q2PJC2, Q9UCB7, Q2MKP0, Q4U0V1, Q2PJC3, Q86WY9, Q9UCB8, Q2MKP2, Q2PJC7, Q2PJC1, Q2PJC5, A4ZPI6, A4ZPI1, A4ZPI2, A4ZPI3, A4ZPI5, A4ZPI8, A4ZPI4, A4ZPI7, P06213, Q17RW0, Q59H98, Q2PJC4_HUMAN, Q2MKN9_HUMAN, Q2PJC2_HUMAN, Q9UCB7_HUMAN, Q2MKP0_HUMAN, Q4U0V1_HUMAN, Q2PJC3_HUMAN, Q86WY9_HUMAN, Q9UCB8_HUMAN, Q2MKP2_HUMAN, Q2PJC7_HUMAN, Q2PJC1_HUMAN, Q2PJC5_HUMAN, A4ZPI6_HUMAN, A4ZPI1_HUMAN, A4ZPI2_HUMAN, A4ZPI3_HUMAN, A4ZPI5_HUMAN, A4ZPI8_HUMAN, A4ZPI4_HUMAN, A4ZPI7_HUMAN, INSR_HUMAN, Q17RW0_HUMAN, Q59H98_HUMAN, P06213-2, IPR000719, IPR002011, IPR008266, IPR001245, IPR003962, IPR000494, IPR003961, IPR006211
Molecules with this sequenceINSR(28-758) [plasma membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
INSR(763-1382) [plasma membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
p-6Y-INSR(763-1382) [plasma membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
INSR(28-758) [endosome membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
p-6Y-INSR(763-1382) [endosome membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
INSR(763-1382) [endosome membrane] UKENBCdOOOOOORHGURPPPPPPPPDDDDDDDD
Tyr972
phospho-NPEY
Component ofphospho-insulin receptor [plasma membrane]
Insulin receptor [plasma membrane]
insulin receptor [endosome membrane]
phospho-insulin receptor [endosome membrane]
activated insulin receptor [plasma membrane]
insulin:insulin receptor [plasma membrane]
activated insulin receptor [endosome membrane]
SHC:activated insulin receptor [plasma membrane]
phospho-SHC: activated insulin receptor [plasma membrane]
phospho-IRS:activated insulin receptor [plasma membrane]
...
List all 12 items
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 1158
O4'-phospho-L-tyrosine at 1162
O4'-phospho-L-tyrosine at 1163
O4'-phospho-L-tyrosine at 1328
O4'-phospho-L-tyrosine at 1330
O4'-phospho-L-tyrosine at 972
DomainsTyr972
phospho-NPEY
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