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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P10721
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Mast/stem cell growth factor receptor Kit shortName:SCFR ecNumber2.7.10.1/ecNumber alternativeName: Piebald trait protein shortName:PBT alternativeName: Proto-oncogene c-Kit alternativeName: Tyrosine-protein kinase Kit alternativeName: p145 c-kit alternativeName: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog cdAntigenNameCD117/cdAntigenName
Links to corresponding entries in other databasesBioGPS Gene:3815
BioGPS Gene:653882
Brenda:2.7.10.1
CTD Gene:3815
CTD Gene:653882
DOCK Blaster:1PKG
DOCK Blaster:1T45
DOCK Blaster:1T46
EC:2.7.10.1
ENSEMBL:ENSG00000157404
GeneCards:P10721
HapMap:NM_000222
HapMap:NM_001093772
IntEnz:2.7.10.1
KEGG Gene:3815
NCBI Gene:3815
NCBI Gene:653882
OMIM:164920
OMIM:172800
OMIM:606764
Orphanet:16308
PRO:P10721
Protein Data Bank:1PKG
Protein Data Bank:1T45
Protein Data Bank:1T46
RefSeq:NM_000222
RefSeq:NM_001093772
RefSeq:NP_000213
RefSeq:NP_001087241
UCSC human:P10721
UniProt:P10721
ZINC_target:P10721
dbSNP Gene:3815
dbSNP Gene:653882
Other identifiers related to this sequenceKIT_HUMAN, B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99, X06182, SM00408, AAC50968, SM00219, 4K94, 2727634, AAH71593, A_14_P135100, IPR016243, X69306, IPR001245, 2727636, A_33_P3303245, X69303, X69301, X69307, ADF36702, 2727644, IPR013098, 2727640, 1PKG, 2727626, EU826594, BC071593, 2727601, 1R01, 2727624, 2727642, CAA29548, 1T45, S67773, ENSG00000157404, AK304031, PF07679, KIT-002, IPR011009, uc010igs.3, 2VIF, 9027509, NP_001087241, 8095110, IPR007110, XM_006714038, CAD27356, GU983671, 4K9E, LRG_307, 2727616, ADF50069, 2727631, IPR003598, Hs.717339, 2727628, BAG64945, X69312, X69314, MIM:601626, 2727639, MIM:606764, NM_001093772, MIM:164920, X69309, AAC50969, Q8TCG9, 2E9W, CCDS47058, HM015525, SM00409, 2727621, KIT, PF07714, CAA49159, X69302, SM00220, HM015526, 3G0F, 1QZK, AC006552, 2727645, 3815, 2727637, 11721613_a_at, PF00047, 2727641, X69311, X69305, HGNC:6342, IPR000719, X69315, 1T46, UPI000006D0DC, A_33_P3407034, EntrezGene:3815, OTTHUMP00000218587, MIM:273300, uc010igr.3, 2727643, A_14_P130973, ENSP00000390987, AAB29529, 2727638, IPR002290, MIM:172800, HPA004471, 2727635, Hs.479754, 1888_s_at, X69316, X69308, 2727633, 2727625, IPR003599, XP_006714101, X69310, CAB003288, X69304, ADF50068, 11746065_a_at, PF00069, U63834, 16966855, 2EC8, 2727602, ACF47630, 3G0E, AJ438313, X69313, 4HVS, 2727620, AC092545, IPR020635, IPR013151, 1QZJ, KIT-001, 2727648, XM_005265742, XM_005265740, A_23_P110253, X06182_s_at, 0000730121, GE59676, CCDS3496, 2727647, XP_005265797, OTTHUMP00000158901, 11721614_a_at, PH_hs_0004671, A_14_P122291, ENST00000288135, XM_005265741, LRG_307t1, ENSP00000288135, XP_005265799, ILMN_1790160, UPI000003F17D, g4557694_3p_a_at, NM_000222, 2727646, NP_000213, 205051_s_at, XP_005265798
Molecules with this sequenceKIT [plasma membrane] UKENNBBCCddOOOORRHHPGPPPURRDDDZ
p-7Y-KIT [plasma membrane] UKENNBBCCddOOOORRHHPGPPPURRDDDZ
p-S741,S746-KIT [plasma membrane] UKENNBBCCddOOOORRHHPGPPPURRDDDZ
p-8Y-KIT [plasma membrane] UKENNBBCCddOOOORRHHPGPPPURRDDDZ
Component ofKIT:sSCF dimer [plasma membrane]
KIT:sSCF dimer:KIT [plasma membrane]
PTPRO:KIT [plasma membrane]
p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]
p-KIT (S741,746):PKC alpha [plasma membrane]
p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane]
PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane]
SHP-1:p-c-Kit complex [plasma membrane]
Tyrosine kinases:p-KIT complex [plasma membrane]
GRB2:SOS1:p-KIT complex [plasma membrane]
...
List all 31 items
Processes where molecules and complexes with this sequence are involved

Immune System

Signal Transduction

Disease

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 570
O4'-phospho-L-tyrosine at 721
O4'-phospho-L-tyrosine at 568
O4'-phospho-L-tyrosine at 823
O4'-phospho-L-tyrosine at 936
O4'-phospho-L-tyrosine at 703
O4'-phospho-L-tyrosine at 730
O4'-phospho-L-tyrosine at 900
O-phospho-L-serine at 746
O-phospho-L-serine at 741
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