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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P31749
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: RAC-alpha serine/threonine-protein kinase ecNumber2.7.11.1/ecNumber alternativeName: Protein kinase B shortName:PKB alternativeName: Protein kinase B alpha shortName:PKB alpha alternativeName: Proto-oncogene c-Akt alternativeName: RAC-PK-alpha
Links to corresponding entries in other databasesBioGPS Gene:207
Brenda:2.7.11.1
CTD Gene:207
DOCK Blaster:1H10
DOCK Blaster:1UNP
DOCK Blaster:1UNQ
DOCK Blaster:1UNR
EC:2.7.11.1
ENSEMBL:ENSG00000142208
GeneCards:P31749
HapMap:NM_001014431
HapMap:NM_001014432
HapMap:NM_005163
IntEnz:2.7.11.1
KEGG Gene:207
NCBI Gene:207
OMIM:164730
Protein Data Bank:1H10
Protein Data Bank:1UNP
Protein Data Bank:1UNQ
Protein Data Bank:1UNR
RefSeq:NM_001014431
RefSeq:NM_001014432
RefSeq:NM_005163
RefSeq:NP_001014431
RefSeq:NP_001014432
RefSeq:NP_005154
UCSC human:P31749
UniProt:P31749
dbSNP Gene:207
Other identifiers related to this sequenceAKT1_HUMAN, B2RAM5, Q9BWB6, ENSG00000142208, ENST00000349310, ENSP00000270202, 1564_at, 207163_s_at, M63167_at, g4885060_3p_a_at, A_14_P108902, A_23_P2960, A_23_P14358, A_32_P455693, CCDS9994, GE58023, BC001737, M63167, AF283830, AF283819, AF283820, AF283821, AF283822, AF283823, AF283824, AF283825, AF283826, AF283827, AF283828, AF283829, BC000479, BC084538, X61037, EntrezGene:207, GI_4885060-S, ILMN_16661, IPI00012866, MIM:164730, 1H10, 1UNP, 1UNQ, 1UNR, AAH01737, AAA36539, AAL55732, AAH00479, AAH84538, CAA43372, NM_001014431, NM_001014432, NM_005163, NP_005154, NP_001014432, NP_001014431, Hs.525622, Q9BV07, P31749, Q9BV07_HUMAN, AKT1_HUMAN, IPR000719, IPR008271, IPR001245, IPR000961, IPR001849
Molecules with this sequenceAKT1 [cytosol] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308,S473-AKT1 [cytosol] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308,S473-AKT1 [nucleoplasm] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308-AKT1 [cytosol] UKENBCdORRRHHHGURRRPPPPDDDD
AKT1 [plasma membrane] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308,S473-AKT1 [plasma membrane] UKENBCdORRRHHHGURRRPPPPDDDD
p-S473-AKT1 [plasma membrane] UKENBCdORRRHHHGURRRPPPPDDDD
AKT1 E17K [plasma membrane] UKENBCdORRRHHHGURRRPPPPDDDD
AKT1 E17K [cytosol] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308,S473-AKT1 E17K [cytosol] UKENBCdORRRHHHGURRRPPPPDDDD
p-S473-AKT1 E17K [plasma membrane] UKENBCdORRRHHHGURRRPPPPDDDD
p-T308,S473-AKT1 E17K [nucleoplasm] UKENBCdORRRHHHGURRRPPPPDDDD
Component ofp-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane]
AKT1 E17K mutant:PIP2 [plasma membrane]
p-S473-AKT1 E17K mutant:PIP2 [plasma membrane]
PIP3:PDK1:active AKT [plasma membrane]
PDK1:AKT:PIP3 [plasma membrane]
AKT:PIP3 [plasma membrane]
p-S-AKT:PIP3 [plasma membrane]
...
List all 16 items
Represented by generalisation(s)AKT [cytosol]
Active AKT [cytosol]
Active AKT [nucleoplasm]
p-AKT1/2 [nucleoplasm]
p-T-AKT [cytosol]
AKT [plasma membrane]
AKT1/PDK1 [plasma membrane]
p-S-AKT [plasma membrane]
AKT/AKT1 E17K mutant [cytosol]
Processes where molecules and complexes with this sequence are involved

Metabolism of RNA

AKT phosphorylates Bad [Homo sapiens]

Signal Transduction

Membrane Trafficking

Gene Expression

Hemostasis

Apoptosis

Disease

Immune System

Metabolism

Developmental Biology

Modifications in molecules with this sequenceO-phospho-L-threonine at 308
O-phospho-L-serine at 473
L-glutamic acid 17 replaced with L-lysine
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