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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P53667
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: LIM domain kinase 1 shortName:LIMK-1 ecNumber2.7.11.1/ecNumber
Links to corresponding entries in other databasesBioGPS Gene:3984
Brenda:2.7.11.1
CTD Gene:3984
EC:2.7.11.1
ENSEMBL:ENSG00000106683
GeneCards:P53667
HapMap:NM_002314
IntEnz:2.7.11.1
KEGG Gene:3984
NCBI Gene:3984
OMIM:194050
OMIM:601329
Orphanet:16358
PRO:P53667
RefSeq:NM_002314
RefSeq:NP_002305
UCSC human:P53667
UniProt:P53667
ZINC_target:P53667
dbSNP Gene:3984
Other identifiers related to this sequenceLIMK1_HUMAN, B7Z6I8, D3DXF4, D3DXF5, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1, 8812460, AAC13885, 3008129, MIM:601329, HGNC:6613, HPA028516, PF07714, 8133413, SM00219, 3S95, EAW69621, AAC13886, Q75MU4, SM00220, 3008113, HPA028064, EAW69622, EAW69623, D26309, 3008141, 11747621_a_at, 11724615_at, IPR001245, 204357_s_at, 8673124, IPR010440, AAS07436, 1015_s_at, SM00132, CCDS5563, PF00412, ILMN_1797362, 3008138, IPR000719, 3008118, g8051616_3p_a_at, g4587498_3p_a_at, 3008142, 3008127, GE59301, LIMK1-001, 3984, OTTHUMP00000160532, 3008130, U63721, NP_002305, SM00228, ILMN_1776708, 0002030541, IPR002290, 3008128, Hs.650078, A_23_P215461, IPR011009, 3008110, 3008123, 3008125, 3008135, 3008140, 3008117, PH_hs_0035415, 3008122, 208372_s_at, LIMK1, 3008143, AF134379, ENSG00000106683, AAS07438, IPR001478, AC005056, U62293_rna1_s_at, AAD25742, CH471200, AK300382, IPR001781, ENSP00000336740, PH_hs_0002901, BAH13274, EntrezGene:3984, UPI000013D678, PF00595, PF00069, uc003uaa.2, NM_002314, 0005050138, 3008119, BAA05371, 3008134, 11724614_at, 3008126, AC005057, 3008111, U62293, AAB17546, PF06293, 17047045, EAW69620, AAB17545, PR00109, 3008131, Hs.647035, ILMN_1698649, IPR020635, OTTHUMP00000211914, 3008109, UPI000002AD44, AAS07437, LIMK1-003, ENSP00000414606, Q75MU0, OTTHUMP00000211915, uc003uab.3, LIMK1-005, ENSP00000444452, UPI0000579D9E, NP_001191355, 3008116, NM_001204426, CCDS56491
Molecules with this sequenceLIMK1 [cytosol] UKENBCdOOORHPGURZ
p-T508-LIMK1 [cytosol] UKENBCdOOORHPGURZ
p-S,T508-LIMK1 [cytosol] UKENBCdOOORHPGURZ
Component ofActive LIMK1 [cytosol]
p-S3-CFL1:p-LIMK [cytosol]
pCofilin: Active LIMK-1 [cytosol]
pLIMK dimer:HSP-90 [cytosol]
Sema3A:Plexin-A1:Neuropilin-1:LIMK-1 [plasma membrane]
Sema3A:Plexin-A1:Neuropilin-1:LIMK:pCofilin-1 [plasma membrane]
Represented by generalisation(s)LIM Kinases [cytosol]
p-LIMK [cytosol]
Processes where molecules and complexes with this sequence are involved

Limk1 phosphorylates Cfl1, inactivating it [Homo sapiens]

Immune System

Developmental Biology

Modifications in molecules with this sequenceO-phospho-L-threonine at 508
O-phospho-L-serine at unknown position
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