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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:Q99707
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Methionine synthase ecNumber2.1.1.13/ecNumber alternativeName: 5-methyltetrahydrofolate--homocysteine methyltransferase alternativeName: Vitamin-B12 dependent methionine synthase shortName:MS
Links to corresponding entries in other databasesBioGPS Gene:4548
Brenda:2.1.1.13
CTD Gene:4548
EC:2.1.1.13
ENSEMBL:ENSG00000116984
GeneCards:Q99707
HapMap:NM_000254
IntEnz:2.1.1.13
KEGG Gene:4548
NCBI Gene:4548
OMIM:156570
OMIM:250940
RefSeq:NM_000254
RefSeq:NP_000245
UCSC human:Q99707
UniProt:Q99707
dbSNP Gene:4548
Other identifiers related to this sequenceMETH_HUMAN, A1L4N8, A9Z1W4, B9EGF7, Q99713, Q99723, ENSG00000116984, ENST00000366576, ENSP00000355535, 203774_at, 38383_at, U73338_at, g4557764_3p_at, A_14_P132244, A_23_P200930, A_23_P200936, CCDS1614, GE592791, GE80903, BC130616, BX641132, AL359259, AL359185, U71285, U75743, U73338, EntrezGene:4548, GI_4557764-S, ILMN_23657, IPI00644782, IPI00742881, IPI00743284, IPI00843871, MIM:156570, MIM:250940, AAI30617, CAE46059, CAH70984, CAH73200, CAH70983, CAH73198, AAC51188, AAB58906, AAB39704, NM_000254, NP_000245, OTTHUMT00000096632, Hs.498187, Hs.605062, Hs.651426, Hs.695660, A1L4N8, Q6MZH4, Q5VXE0, Q5VXE1, Q99707, A1L4N8_HUMAN, Q6MZH4_HUMAN, Q5VXE0_HUMAN, Q5VXE1_HUMAN, METH_HUMAN, IPR000489, IPR003726, IPR003759, IPR004223, IPR006158
Molecules with this sequenceMTR [cytosol] UKENBCdOORHGUR
MTR H920D [cytosol] UKENBCdOORHGUR
MTR E1204* [cytosol] UKENBCdOORHGUR
MTR A410P [cytosol] UKENBCdOORHGUR
MTR R585* [cytosol] UKENBCdOORHGUR
MTR Ile881 [cytosol] UKENBCdOORHGUR
MTR P1173L [cytosol] UKENBCdOORHGUR
Component ofMTR:Zn2+ [cytosol]
MTR:Zn2+:cob(I)alamin [cytosol]
MTR:Zn2+:cob(II)alamin [cytosol]
MTR:Zn2+:MeCbl [cytosol]
MTRR:MTR [cytosol]
MTRR:MTR(cob(I)alamin) [cytosol]
MTRR:MTR(cob(II)alamin) [cytosol]
MTRR:MTR(MeCbl) [cytosol]
Represented by generalisation(s)MTR mutants [cytosol]
Processes where molecules and complexes with this sequence are involved

Metabolism

Disease

Modifications in molecules with this sequenceL-proline 1173 replaced with L-leucine
L-histidine 920 replaced with L-aspartic acid
L-isoleucine 881 replaced with unknown
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