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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P49137
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: MAP kinase-activated protein kinase 2 shortName:MAPK-activated protein kinase 2 shortName:MAPKAP kinase 2 shortName:MAPKAP-K2 shortName:MAPKAPK-2 shortName:MK-2 shortName:MK2 ecNumber2.7.11.1/ecNumber
Links to corresponding entries in other databasesBioGPS Gene:9261
Brenda:2.7.11.1
CTD Gene:9261
DOCK Blaster:1KWP
DOCK Blaster:1NXK
DOCK Blaster:1NY3
EC:2.7.11.1
ENSEMBL:ENSG00000162889
GeneCards:P49137
HapMap:NM_032960
IntEnz:2.7.11.1
KEGG Gene:9261
NCBI Gene:9261
OMIM:602006
PRO:P49137
Protein Data Bank:1KWP
Protein Data Bank:1NXK
Protein Data Bank:1NY3
RefSeq:NM_032960
RefSeq:NP_116584
UCSC human:P49137
UniProt:P49137
dbSNP Gene:9261
Other identifiers related to this sequenceMAPK2_HUMAN, Q5SY30, Q5SY41, Q8IYD6, 2376956, PF07714, ENSG00000162889, BC036060, SM00219, 3KA0, 0000070164, SM00220, 2JBP, 3R30, 7909236, CAI13543, 215050_x_at, 2376951, X75346, IPR001245, 3FYJ, 2OZA, 3FPM, IPR010440, AL591846, 2376954, 8280084, 3KC3, 16676643, CAI13544, U12779_at, uc001hel.2, EAW93526, 1439_s_at, 3A2C, AAH36060, 2376953, 1469_at, 2376923, IPR000719, 2376926, 2376959, AAA20851, 3R2B, 2376950, 3FYK, 2376924, MIM:602006, BC052584, X75346_s_at, MAPKAPK2-002, 3M42, EAW93529, 2PZY, 2P3G, A_14_P129763, OTTHUMP00000034532, 3M2W, 2376968, 3R2Y, IPR002290, NP_004750, IPR011009, 2376925, 2JBO, 1NXK, ENSP00000294981, 2376962, 2376949, U12779, UPI000002AE18, g10863900_3p_a_at, 3WI6, 2376967, 2376964, 2ONL, 2376966, 2376965, HPA045556, AAH52584, 2OKR, NM_004759, CCDS1466, CAB010297, EntrezGene:9261, HGNC:6887, CAA53094, 2376957, PF00069, ILMN_1656144, XP_005273410, 1KWP, 11730896_a_at, A_23_P350467, 1NY3, 9261, PF06293, 201461_s_at, 3KGA, CH471100, Hs.643566, 8179591, MAPKAPK2, IPR020635, 36180_s_at, NM_032960, ENSP00000356070, 201460_at, Hs.75074.0.A2_3p_at, MAPKAPK2-001, A_23_P201483, UPI0000112289, 0006290551, ILMN_1774844, OTTHUMP00000034531, 36179_at, uc001hem.2, NP_116584, CCDS31001, PH_hs_0004270, 11719368_s_at
Molecules with this sequenceMAPKAPK2 [cytosol] UKENBCdORHPGPPPURDDD
p-T222,S272,T334-MAPKAPK2 [cytosol] UKENBCdORHPGPPPURDDD
p-T222,S272-MAPKAPK2 [nucleoplasm] UKENBCdORHPGPPPURDDD
MAPKAPK2 [nucleoplasm] UKENBCdORHPGPPPURDDD
p-T222,S272,T334-MAPKAPK2 [nucleoplasm] UKENBCdORHPGPPPURDDD
Component ofp-p38 MAPK:p-MAPKAPK2/3 [nucleoplasm]
p38 MAPK:MAPKAPK2/3 [nucleoplasm]
phospho-p38 MAPK : phospho MAPKAPK2 or phospho MaPKAPK3 [cytosol]
phospho-p38 MAPK: MAPKAPK2/3 [nucleoplasm]
Represented by generalisation(s)MAPKAP kinase [cytosol]
Active MAPKAP kinase [cytosol]
MAPKAP2/3 [nucleoplasm]
Active MAPKAP kinase [nucleoplasm]
Processes where molecules and complexes with this sequence are involved

Metabolism of RNA

Signal Transduction

Immune System

Gene Expression

Metabolism

Cellular responses to stress

TRAF6 Mediated Induction of proinflammatory cytokines

Modifications in molecules with this sequenceO-phospho-L-serine at 272
O-phospho-L-threonine at 222
O-phospho-L-threonine at 334
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