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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P04000
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Long-wave-sensitive opsin 1 alternativeName: Red cone photoreceptor pigment alternativeName: Red-sensitive opsin shortName:ROP
Links to corresponding entries in other databasesBioGPS Gene:5956
CTD Gene:5956
DOCK Blaster:1KPX
ENSEMBL:ENSG00000102076
GeneCards:P04000
HapMap:NM_020061
NCBI Gene:5956
OMIM:303900
Protein Data Bank:1KPX
RefSeq:NM_020061
RefSeq:NP_064445
UCSC human:P04000
UniProt:P04000
dbSNP Gene:5956
Other identifiers related to this sequenceOPSR_HUMAN, ENSG00000102076, ENST00000369951, ENSP00000358967, 207364_at, 221327_s_at, 31715_at, K03494_s_at, Z68193_at, g4503176_3p_at, g4503964_3p_s_at, 221327_3p_s_at, A_23_P114374, CCDS14742, GE567795, CR749814, Z68193, M13305, M13300, M13301, M13302, M13303, M13304, EntrezGene:5956, GI_9910525-S, ILMN_2602, IPI00021724, MIM:303900, OTTHUMT00000082839, 1KPX, CAH18674, AAB59524, CAA92342, NM_020061, NP_064445, Hs.592247, Q68CR4, P04000, Q68CR4_HUMAN, OPSR_HUMAN, IPR000276, IPR001760, IPR013032, IPR000378, IPR002206
Molecules with this sequenceOPN1LW [photoreceptor outer segment membrane] UENBCdORHGURPD
OPN1LW G338E [endoplasmic reticulum lumen] UENBCdORHGURPD
OPN1LW R247* [endoplasmic reticulum lumen] UENBCdORHGURPD
OPN1LW C203R [endoplasmic reticulum lumen] UENBCdORHGURPD
OPN1LW P307L [endoplasmic reticulum lumen] UENBCdORHGURPD
at-retinyl-OPN1LW [photoreceptor outer segment membrane] UENBCdORHGURPD
11cRAL-OPN1LW [photoreceptor outer segment membrane] UENBCdORHGURPD
Component ofOpsins:photon [plasma membrane]
Represented by generalisation(s)Light-sensing opsins [plasma membrane]
Cone apo-opsins [photoreceptor outer segment membrane]
OPN1MW/OPN1LW [photoreceptor outer segment membrane]
OPN1SW/OPN1LW [photoreceptor outer segment membrane]
OPN1LW mutants [endoplasmic reticulum lumen]
at-retinyl-cone opsins [photoreceptor outer segment membrane]
11c-retinyl-cone opsins [photoreceptor outer segment membrane]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Disease

Modifications in molecules with this sequenceL-proline 307 replaced with L-leucine
L-arginine 247 replaced with unknown
glycine 338 replaced with L-glutamic acid
L-cysteine 203 replaced with L-arginine
atRAL-lysine (all-trans-retinyl group) at unknown position
11cRAL-lysine (11c-retinyl group) at unknown position
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