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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P04000
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Long-wave-sensitive opsin 1 alternativeName: Red cone photoreceptor pigment alternativeName: Red-sensitive opsin shortName:ROP
Links to corresponding entries in other databasesBioGPS Gene:5956
CTD Gene:5956
DOCK Blaster:1KPX
ENSEMBL:ENSG00000102076
GeneCards:P04000
HapMap:NM_020061
NCBI Gene:5956
OMIM:303900
Orphanet:16592
PRO:P04000
Protein Data Bank:1KPX
RefSeq:NM_020061
RefSeq:NP_064445
UCSC human:P04000
UniProt:P04000
dbSNP Gene:5956
Other identifiers related to this sequenceOPSR_HUMAN, 3996209, IPR017452, 5956, 3996174, NM_020061, PF10324, 1KPX, 3996175, GE567795, 3996152, 3996149, PF00001, AAB59524, 3996180, 3996184, 11735456_s_at, Z68193_at, g4503964_3p_s_at, 8170825, OTTHUMP00000032193, MIM:303900, PR00237, MIM:300822, 3996208, 221327_3p_s_at, M13302, OPN1LW, M13303, 3996215, IPR001760, 3996158, ENSP00000358967, 3996145, 3996203, IPR019427, CCDS14742, A_23_P96623, ENSG00000102076, IPR000276, K03494_s_at, 3996177, NP_064445, PR00238, 3996216, 8170816, 3996178, 3996205, IPR000378, ILMN_3241647, Hs.592247, OPN1LW-001, EntrezGene:5956, 17108254, 3996157, M13301, 3996202, 3996179, M13300, ILMN_1677153, MIM:303700, 3996146, 17108244, 3996148, HGNC:9936, 3996185, 221327_s_at, UPI0002AB8036, 3996151, Z68193, 3996147, PR00575, 0003130075, 8170811, uc033fax.1, GE580526, M13304, M13305, CAA92342, 17108234
Molecules with this sequenceOPN1LW [photoreceptor outer segment membrane] UENBCdOORHPGPURD
OPN1LW G338E [endoplasmic reticulum lumen] UENBCdOORHPGPURD
OPN1LW R247* [endoplasmic reticulum lumen] UENBCdOORHPGPURD
OPN1LW C203R [endoplasmic reticulum lumen] UENBCdOORHPGPURD
OPN1LW P307L [endoplasmic reticulum lumen] UENBCdOORHPGPURD
at-retinyl-OPN1LW [photoreceptor outer segment membrane] UENBCdOORHPGPURD
11cRAL-OPN1LW [photoreceptor outer segment membrane] UENBCdOORHPGPURD
Component ofOpsins:photon [plasma membrane]
Represented by generalisation(s)Light-sensing opsins [plasma membrane]
Cone apo-opsins [photoreceptor outer segment membrane]
OPN1MW/OPN1LW [photoreceptor outer segment membrane]
OPN1SW/OPN1LW [photoreceptor outer segment membrane]
OPN1LW mutants [endoplasmic reticulum lumen]
at-retinyl-cone opsins [photoreceptor outer segment membrane]
11c-retinyl-cone opsins [photoreceptor outer segment membrane]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Disease

Modifications in molecules with this sequenceL-proline 307 replaced with L-leucine
L-arginine 247 replaced with unknown
glycine 338 replaced with L-glutamic acid
L-cysteine 203 replaced with L-arginine
atRAL-lysine (all-trans-retinyl group) at unknown position
11cRAL-lysine (11c-retinyl group) at unknown position
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