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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P05121
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Plasminogen activator inhibitor 1 shortName:PAI shortName:PAI-1 alternativeName: Endothelial plasminogen activator inhibitor alternativeName: Serpin E1
Links to corresponding entries in other databasesBioGPS Gene:5054
CTD Gene:5054
DOCK Blaster:1A7C
DOCK Blaster:1B3K
DOCK Blaster:1C5G
DOCK Blaster:1DB2
DOCK Blaster:1DVM
DOCK Blaster:1DVN
DOCK Blaster:1LJ5
DOCK Blaster:1OC0
DOCK Blaster:9PAI
ENSEMBL:ENSG00000106366
GeneCards:P05121
HapMap:NM_000602
KEGG Gene:5054
NCBI Gene:5054
OMIM:173360
OMIM:188050
Orphanet:15273
PRO:P05121
Protein Data Bank:1A7C
Protein Data Bank:1B3K
Protein Data Bank:1C5G
Protein Data Bank:1DB2
Protein Data Bank:1DVM
Protein Data Bank:1DVN
Protein Data Bank:1LJ5
Protein Data Bank:1OC0
Protein Data Bank:9PAI
RefSeq:NM_000602
RefSeq:NP_000593
UCSC human:P05121
UniProt:P05121
ZINC_target:P05121
dbSNP Gene:5054
Other identifiers related to this sequencePAI1_HUMAN, B7Z4S0, F8WD53, 202627_s_at, 3016154, 0006840139, X12701, CAB51606, 3UT3, EntrezGene:5054, 4G8O, 1LJ5, CAB51738, 3016166, SERPINE1, ENSG00000106366, 9PAI, X13344, CAA28442, M22318, 1DVM, X04731, CAB51739, UPI0000000CAB, 3CVM, 5054, IPR023796, X13338, 3Q02, M22316, X13339, SM00093, 4AQH, PH_hs_0024995, A_24_P158089, AC004876, X13342, 1A7C, 4IC0, X13323, BAH12656, 1B3K, CAA28438, uc003uxt.4, 1C5G, g10835158_3p_a_at, 3016168, BAH14596, 11715636_a_at, AAK60338, A_14_P119092, X13343, ENSP00000223095, X04744, AAA60008, 17049676, AAA60003, CAA31208, CAA31729, 2891140, J03764_at, 672_at, 3EOX, 3016163, Hs.414795, 11757312_x_at, CAB51737, AK297728, M22319, 3Q03, HPA050039, 8135069, 3016161, CAB51607, 3PB1, AAA60009, Hs.741440, 4G8R, 3016150, HGNC:8583, CAA31722, X13345, M22314, M22321, 202628_s_at, M22317, PF00079, 11746856_a_at, SERPINE1-001, X04729, B7Z1D9, 1OC0, CAA28444, 1DB2, 1DVN, M22320, OTTHUMP00000211478, M16006, J03764, AK316225, MIM:173360, A_14_P105272, 3016149, MIM:613329, M14083, X04429, AAA60007, X13341, AK293248, 24172014, NP_000593, ILMN_1744381, BC010860, 3016158, CAB51639, CCDS5711, AAD45828, Hs.82085.0.S1_3p_a_at, CAA28025, AAH10860, 3R4L, X04729_s_at, BAH11475, GE57824, 3097076, NM_000602, X13340, M22315, 3016172, 3016170, 3016153, 38125_at, AF386492, B7ZAB0
Molecules with this sequenceSERPINE1 [extracellular region] UKENBCdOOORHPGPPPPPPPPPURDDDDDDDDDZ
SERPINE1 [platelet alpha granule lumen] UKENBCdOOORHPGPPPPPPPPPURDDDDDDDDDZ
SERPINE1 [extracellular region] UKENBCdOOORHPGPPPPPPPPPURDDDDDDDDDZ
SERPINE1 [plasma membrane] UKENBCdOOORHPGPPPPPPPPPURDDDDDDDDDZ
Component offibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 [extracellular region]
fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 [extracellular region]
PAI-1:urokinase plasminogen activator (two-chain):uPAR [plasma membrane]
Vitronectin:Plasminogen activator inhibitor 1 [extracellular region]
Represented by generalisation(s)Platelet alpha granule contents [platelet alpha granule lumen]
Platelet alpha granule contents [extracellular region]
SERPINE1-like proteins [extracellular region]
SERPINE1-like proteins [plasma membrane]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Extracellular matrix organization

Circadian Clock

Gene Expression

Hemostasis

Disease

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