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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P16112
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Aggrecan core protein alternativeName: Cartilage-specific proteoglycan core protein shortName:CSPCP alternativeName: Chondroitin sulfate proteoglycan core protein 1 shortName:Chondroitin sulfate proteoglycan 1 component recommendedName: Aggrecan core protein 2 /component
Links to corresponding entries in other databasesBioGPS Gene:176
CTD Gene:176
ENSEMBL:ENSG00000157766
GeneCards:P16112
HapMap:NM_013227
NCBI Gene:176
OMIM:155760
OMIM:608361
Orphanet:15068
PRO:P16112
RefSeq:NM_013227
RefSeq:NP_037359
UCSC human:P16112
UniProt:P16112
dbSNP Gene:176
Other identifiers related to this sequencePGCA_HUMAN, Q13650, Q9UCD3, Q9UCP4, Q9UCP5, Q9UDE0
Molecules with this sequenceN-glycan ACAN [Golgi lumen] UENBCdOOORHPGUR
Keratan(4)-ACAN [Golgi lumen] UENBCdOOORHPGUR
KS(2)-ACAN [lysosomal lumen] UENBCdOOORHPGUR
KS(2)-ACAN [Golgi lumen] UENBCdOOORHPGUR
Keratan(3)-ACAN [Golgi lumen] UENBCdOOORHPGUR
Keratan(1)-ACAN [Golgi lumen] UENBCdOOORHPGUR
Gal-glycan ACAN [Golgi lumen] UENBCdOOORHPGUR
KS(1)-ACAN [Golgi lumen] UENBCdOOORHPGUR
KS(2)-ACAN [extracellular region] UENBCdOOORHPGUR
Keratan(2)-ACAN [Golgi lumen] UENBCdOOORHPGUR
ACAN [lysosomal lumen] UENBCdOOORHPGUR
KS(2),CSE-ACAN [extracellular region] UENBCdOOORHPGUR
KS(2),C4S-ACAN [extracellular region] UENBCdOOORHPGUR
KS(2),C6S-ACAN [extracellular region] UENBCdOOORHPGUR
KS(2),C4S-ACAN(393-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),C6S-ACAN(393-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),C4S-ACAN(17-392) [extracellular region] UENBCdOOORHPGUR
KS(2),CSE-ACAN(393-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),C6S-ACAN(17-392) [extracellular region] UENBCdOOORHPGUR
KS(2),CSE-ACAN(17-392) [extracellular region] UENBCdOOORHPGUR
KS(2),C6S-ACAN(17-360) [extracellular region] UENBCdOOORHPGUR
KS(2),C4S-ACAN(361-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),C6S-ACAN(361-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),CSE-ACAN(361-2415) [extracellular region] UENBCdOOORHPGUR
KS(2),CSE-ACAN(17-360) [extracellular region] UENBCdOOORHPGUR
KS(2),C4S-ACAN(17-360) [extracellular region] UENBCdOOORHPGUR
Component ofAggrecan:HA:HAPLN1 [extracellular region]
COMP pentamer:COMP interactors [extracellular region]
Tenascins C, R, (X, N):Lecticans [extracellular region]
Represented by generalisation(s)N-glycan-protein [Golgi lumen]
Keratan(4)-PG [Golgi lumen]
KSPG(2) [lysosomal lumen]
KSPG(2) [Golgi lumen]
Keratan(3)-PG [Golgi lumen]
Keratan(1)-PG [Golgi lumen]
Gal-glycan-protein [Golgi lumen]
KSPG(1) [Golgi lumen]
KSPG(2) [extracellular region]
Keratan(2)-PG [Golgi lumen]
KS core proteins [lysosomal lumen]
Aggrecan [extracellular region]
Aggrecan(393-2415) [extracellular region]
Aggrecan(17-392) [extracellular region]
Aggrecan(17-360) [extracellular region]
Aggrecan(361-2415) [extracellular region]
B4GALT1 substrates [Golgi lumen]
COMP interactors [extracellular region]
Lecticans [extracellular region]
Processes where molecules and complexes with this sequence are involved

Extracellular matrix organization

Metabolism

Disease

Modifications in molecules with this sequenceN4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63488) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63499) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63520) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63494) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63522) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63500) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63495) at unknown position
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63492) at unknown position
O-xylosyl-L-serine (beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc6S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group) at unknown position
O-xylosyl-L-serine (beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc4,6S2-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group) at unknown position
O-xylosyl-L-serine (beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group) at unknown position
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