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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P04070
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Vitamin K-dependent protein C ecNumber3.4.21.69/ecNumber alternativeName: Anticoagulant protein C alternativeName: Autoprothrombin IIA alternativeName: Blood coagulation factor XIV component recommendedName: Vitamin K-dependent protein C light chain /component component recommendedName: Vitamin K-dependent protein C heavy chain /component component recommendedName: Activation peptide /component
Links to corresponding entries in other databasesBioGPS Gene:5624
Brenda:3.4.21.69
CTD Gene:5624
DOCK Blaster:1AUT
DOCK Blaster:1PCU
DOCK Blaster:2PCT
EC:3.4.21.69
ENSEMBL:ENSG00000115718
GeneCards:P04070
HapMap:NM_000312
IntEnz:3.4.21.69
KEGG Gene:5624
NCBI Gene:5624
OMIM:176860
OMIM:188050
Orphanet:15143
PRO:P04070
Protein Data Bank:1AUT
Protein Data Bank:1PCU
Protein Data Bank:2PCT
RefSeq:NM_000312
RefSeq:NP_000303
UCSC human:P04070
UniProt:P04070
ZINC_target:P04070
dbSNP Gene:5624
Other identifiers related to this sequencePROC_HUMAN, B4DPQ7, Q15189, Q15190, Q16001, Q53S74, Q9UC55, K02059, ENSP00000234071, IPR001314, AAB26335, XM_006712633, B4DPC8, 2504610, UPI0000001646, CCDS2145, BAG60669, BAC21170, XP_005263772, MIM:176860, 2PCT, M12686, 2504607, IPR001881, AAY15044, M11228, 1LQV, 2504611, SM00179, 3JTC, 8045018, M12685, 4DT7, 16885324, Hs.224698, AB083698, 2504605, 2504596, 11743844_a_at, 206259_at, BAC21171, A_33_P3379922, XP_005263774, 2504602, 2991887, IPR001254, AAH34377, 2504612, HPA005550, MIM:612283, M12684, 2504598, BC034377, AK298280, 2437584, XM_005263715, IPR000294, PROC-001, M12683, 5624, AAK56377, PR00722, AAQ24849, 2504608, M12712, EAW95320, ILMN_1687721, 2504609, X02750_at, SM00020, A_23_P40096, NM_000312, AAA60166, 11745349_a_at, PR00001, 39255_at, g4506114_3p_at, IPR012224, 1AUT, Q8J004, AC068282, S76088, X02750, CAA26528, XM_005263717, AF378903, ENSG00000115718, GE59643, 2504613, S76090, PF00594, S58668, SM00069, XP_006712696, AB083699, CAB016721, SM00181, 2504606, AAA60164, PF00089, Q8J003, HGNC:9451, 3F6U, OTTHUMP00000162263, 1PCU, IPR000742, AY348553, Q6V7X9, 2504604, uc002tok.3, AK298454, AAA60165, M12687, ILMN_1714316, NP_000303, PROC, E7EU72, MIM:612304, PH_hs_0000316, CH471103, CAB016792, BAG60540, E7EVH6, IPR009003, EntrezGene:5624, 0002760408
Molecules with this sequence8xCbxE-3D-PROC(43-197) [extracellular region] UKENBCdOOORHPGPPPURDDDZ
PROC(200-461) [extracellular region] UKENBCdOOORHPGPPPURDDDZ
PROC(212-461) [extracellular region] UKENBCdOOORHPGPPPURDDDZ
PROC(200-211) [extracellular region] UKENBCdOOORHPGPPPURDDDZ
8xCbxE-3D-PROC(33-197) [endoplasmic reticulum lumen] UKENBCdOOORHPGPPPURDDDZ
8xCbxE-3D-PROC(33-197) [Golgi lumen] UKENBCdOOORHPGPPPURDDDZ
8xCbxE-3D-PROC(43-197) [Golgi lumen] UKENBCdOOORHPGPPPURDDDZ
3D-PROC(33-197) [endoplasmic reticulum lumen] UKENBCdOOORHPGPPPURDDDZ
PROC(33-42) [Golgi lumen] UKENBCdOOORHPGPPPURDDDZ
PROC(200-461) [endoplasmic reticulum lumen] UKENBCdOOORHPGPPPURDDDZ
PROC(200-461) [Golgi lumen] UKENBCdOOORHPGPPPURDDDZ
Component ofActivated protein C [extracellular region]
Activated protein C:Protein S [plasma membrane]
pro-protein C [endoplasmic reticulum lumen]
pro-protein C [Golgi lumen]
pro-protein C, uncarboxylated [endoplasmic reticulum lumen]
PROCR:Activated protein C [plasma membrane]
PROCR:Protein C [plasma membrane]
Protein C [extracellular region]
protein C [Golgi lumen]
SERPINA5:Activated protein C [extracellular region]
Processes where molecules and complexes with this sequence are involved

Metabolism of proteins

Hemostasis

Modifications in molecules with this sequenceL-gamma-carboxyglutamic acid at 71
L-gamma-carboxyglutamic acid at 68
L-gamma-carboxyglutamic acid at 67
L-gamma-carboxyglutamic acid at 62
L-gamma-carboxyglutamic acid at 61
L-gamma-carboxyglutamic acid at 58
L-gamma-carboxyglutamic acid at 56
L-gamma-carboxyglutamic acid at 49
(2S,3R)-3-hydroxyaspartic acid at 113
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