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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:Q07889
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Son of sevenless homolog 1 shortName:SOS-1
Links to corresponding entries in other databasesBioGPS Gene:6654
CTD Gene:6654
DOCK Blaster:1AWE
DOCK Blaster:1BKD
DOCK Blaster:1DBH
DOCK Blaster:1NVU
DOCK Blaster:1NVV
DOCK Blaster:1NVW
DOCK Blaster:1NVX
DOCK Blaster:1Q9C
DOCK Blaster:1XD2
DOCK Blaster:1XD4
DOCK Blaster:1XDV
DOCK Blaster:2II0
ENSEMBL:ENSG00000115904
GeneCards:Q07889
HapMap:NM_005633
KEGG Gene:6654
NCBI Gene:6654
OMIM:135300
OMIM:182530
OMIM:610733
Orphanet:15537
PRO:Q07889
Protein Data Bank:1AWE
Protein Data Bank:1BKD
Protein Data Bank:1DBH
Protein Data Bank:1NVU
Protein Data Bank:1NVV
Protein Data Bank:1NVW
Protein Data Bank:1NVX
Protein Data Bank:1Q9C
Protein Data Bank:1XD2
Protein Data Bank:1XD4
Protein Data Bank:1XDV
Protein Data Bank:2II0
RefSeq:NM_005633
RefSeq:NP_005624
UCSC human:Q07889
UniProt:Q07889
dbSNP Gene:6654
Other identifiers related to this sequenceSOS1_HUMAN, A8K2G3, L13857, SM00325, Hs.7312.0.A1_3p_at, MIM:610733, 2549115, Hs.604256, 2549110, 16896710, 2549097, 2549103, 1BKD, IPR009072, 227426_at, 3KSY, 2549125, 8276400, 2549117, IPR001895, CCDS1802, A_23_P343808, AK290228, 1NVX, GE57636, 212777_at, BAF82917, 2549122, PF00617, 11720895_at, PF00618, 46678_at, 2549096, 0006130692, 2549102, 1NVU, ENSG00000115904, 2549098, CAB005396, PH_hs_0016186, AAA35913, UPI0000135CF0, 2549100, SOS1, AC019171, 11720893_s_at, 2549106, 2549101, MIM:135300, ILMN_1767135, 4NYJ, PH_hs_0047392, 11720894_a_at, AAX93186, AF106953, SOS1-001, C9K0N6, Hs.326392.1.A2_3p_at, 2549126, OTTHUMP00000128306, 2II0, 1XD4, 2549112, 1Q9C, 1AWE, 2549123, 2548968, 1XD2, CH471053, AC092672, 2549132, 4NYM, AAF04460, 10995566, AAY24202, 2549094, IPR007125, Q9UKX9, 2549113, SM00229, 2549131, 2549114, ENSP00000387784, 212780_at, 2549133, PF00125, IPR000651, 2549093, EAX00351, 2549147, PF00621, 6654, EntrezGene:6654, IPR000219, 2549109, Hs.326392.1.A1_3p_at, A_33_P3356406, IPR001849, 2549099, 2549134, NM_005633, MIM:182530, 2549118, IPR023578, 1NVW, 8051670, HGNC:11187, Hs.709893, 2549095, 2549111, 2549116, PF00169, uc002rrk.4, 1XDV, HPA012613, 2549128, 303_at, Q53SF8, 2549119, 1NVV, SM00233, SM00147, 1DBH, 33260_at, 11720892_at, 4NYI, NP_005624, SOS1-201, ENSP00000384675
Molecules with this sequenceSOS1 [cytosol] UKENBCdOOOORHPGPPPPPPPPPPPPURDDDDDDDDDDDD
p-4S-SOS1 [cytosol] UKENBCdOOOORHPGPPPPPPPPPPPPURDDDDDDDDDDDD
SOS1 [plasma membrane] UKENBCdOOOORHPGPPPPPPPPPPPPURDDDDDDDDDDDD
Component ofGRB2:SOS1 [cytosol]
Crk:SOS [cytosol]
SOS-1 bound to Tie2:Grb2 [plasma membrane]
SOS bound to Grb2:pFADK1 [plasma membrane]
pFAK:Grb2:Sos [cytosol]
BLNK:GRB2:SOS1:CIN85:CBL [cytosol]
p-BLNK:GRB2:SOS1:CIN85:CBL [plasma membrane]
GRB2:SOS:Phospho-SHC [cytosol]
GRB2:SOS:IRS-P [cytosol]
EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane]
...
List all 53 items
Represented by generalisation(s)SOS [cytosol]
GEF [cytosol]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Immune System

Hemostasis

Developmental Biology

Disease

Modifications in molecules with this sequenceO-phospho-L-serine at 1132
O-phospho-L-serine at 1167
O-phospho-L-serine at 1193
O-phospho-L-serine at 1178
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