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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P35968
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Vascular endothelial growth factor receptor 2 shortName:VEGFR-2 ecNumber2.7.10.1/ecNumber alternativeName: Fetal liver kinase 1 shortName:FLK-1 alternativeName: Kinase insert domain receptor shortName:KDR alternativeName: Protein-tyrosine kinase receptor flk-1 cdAntigenNameCD309/cdAntigenName
Links to corresponding entries in other databasesBioGPS Gene:3791
Brenda:2.7.10.1
CTD Gene:3791
DOCK Blaster:1VR2
DOCK Blaster:1Y6A
DOCK Blaster:1Y6B
DOCK Blaster:1YWN
EC:2.7.10.1
ENSEMBL:ENSG00000128052
GeneCards:P35968
HapMap:NM_002253
IntEnz:2.7.10.1
KEGG Gene:3791
NCBI Gene:3791
OMIM:191306
Orphanet:19140
PRO:P35968
Protein Data Bank:1VR2
Protein Data Bank:1Y6A
Protein Data Bank:1Y6B
Protein Data Bank:1YWN
RefSeq:NM_002253
RefSeq:NP_002244
UCSC human:P35968
UniProt:P35968
dbSNP Gene:3791
Other identifiers related to this sequenceVGFR2_HUMAN, A2RRS0, B5A925, C5IFA0, O60723, Q14178, 3S35, 3DTW, B4DEK3, SM00408, 3791, SM00219, ILMN_1686405, 2769848, 2M59, CAA43837, IPR001245, 1YWN, 1Y6A, 2769853, 2769850, 2769862, 1VR2, AK293668, 2769826, PF07686, 2769845, 2769820, 2769831, 2769811, 2XIR, 2769840, IPR013098, 3CPC, 2769856, KDR, 1954_at, 2769816, 3V2A, UPI000003AE04, 2769828, X61656, 2P2I, 2769818, 3VNT, 3B8R, 2769834, 2769821, 3VHK, PF07679, IPR011009, 3CPB, 4AGD, AAB88005, PR01834, IPR007110, MIM:602089, FJ899739, X89776, 3KVQ, 2769832, PR01832, 16976029, EU826563, IPR003598, g11321596_3p_at, HGNC:6307, IPR013106, 2QU6, 2X1W, CAA61916, CCDS3497, 2769814, 2769849, 2769824, 11739315_at, 3C7Q, 2769842, 2769857, SM00409, 4ASD, 2769827, IPR013162, 2769815, PF07714, 3VHE, 2769863, 2769819, AF035121, 1417831, 690_s_at, 2OH4, SM00220, 2RL5, 4ASE, 1Y6B, L04947, 2769817, ENSG00000128052, CAB004028, 0006590341, AC021220, 4AG8, 8100393, A_24_P71973, 11739316_at, 3S37, BC131822, PF00047, PF08205, AAA59459, 3CJG, 2P2H, ACR78514, 2769860, 3EFL, IPR000719, GE54268, 2769835, 3CP9, ENSP00000263923, 2769851, AC111194, MIM:191306, 3U6J, Hs.479756, PH_hs_0001165, 2769825, 2769812, OTTHUMP00000158928, 203934_at, 4AGC, IPR002290, 3EWH, 2769837, 2769833, 2769813, 2769852, 3CJF, 2769822, 3BE2, IPR003599, NP_002244, A_23_P58419, BAG57114, uc003has.3, KDR-001, PF00069, NM_002253, 2QU5, 3V6B, 2X1X, AAC16450, 3VID, 2769839, IPR009136, L04947_at, 2769861, 3S36, 3VO3, AF063658, AAI31823, EntrezGene:3791, 3B8Q, IPR020635, IPR013151, ACF47599
Molecules with this sequenceVEGFR2 [plasma membrane] UKENBCdOORHPGPPPPURDDDD
p-6Y-VEGFR2 [plasma membrane] UKENBCdOORHPGPPPPURDDDD
Component ofVEGFR2 dimer [plasma membrane]
HSPG2(3687-4391):KDR [plasma membrane]
p-6Y-VEGFR2 dimer [plasma membrane]
VEGFA-165 dimer:VEGFR2 dimer [plasma membrane]
NRP1:VEGFR2 dimer [plasma membrane]
VEGFR2:VEGFA,C,D [plasma membrane]
VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]
VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane]
VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane]
VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
...
List all 46 items
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Extracellular matrix organization

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 1054
O4'-phospho-L-tyrosine at 1059
O4'-phospho-L-tyrosine at 951
O4'-phospho-L-tyrosine at 1214
O4'-phospho-L-tyrosine at 1175
O4'-phospho-L-tyrosine at 801
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