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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Class:IdReferenceGeneProduct:67444
_displayNameUniProt:P18074 ERCC2
_timestamp2014-11-19 11:07:05
checksum746C0888CDF2E331
commentCATALYTIC ACTIVITY ATP + H(2)O = ADP + phosphate.
crossReference[DatabaseIdentifier:6568115] PRO:P18074
[DatabaseIdentifier:6611074] GeneCards:P18074
[DatabaseIdentifier:6635617] UCSC human:P18074
[DatabaseIdentifier:6646464] RefSeq:NP_000391
[DatabaseIdentifier:6717409] HMDB_protein:HMDBP08717
descriptionrecommendedName: TFIIH basal transcription factor complex helicase XPD subunit ecNumber3.6.4.12/ecNumber alternativeName: Basic transcription factor 2 80 kDa subunit shortName:BTF2 p80 alternativeName: CXPD alternativeName: DNA excision repair protein ERCC-2 alternativeName: DNA repair protein complementing XP-D cells alternativeName: TFIIH basal transcription factor complex 80 kDa subunit shortName:TFIIH 80 kDa subunit shortName:TFIIH p80 alternativeName: Xeroderma pigmentosum group D-complementing protein
geneNameERCC2
XPD
XPDC
identifierP18074
isSequenceChangedFALSE
keyword4Fe-4S
Alternative splicing
ATP-binding
Cataract
Chromosome partition
Cockayne syndrome
Complete proteome
Cytoplasm
Cytoskeleton
Deafness
Disease mutation
DNA damage
DNA repair
DNA-binding
Dwarfism
Helicase
Host-virus interaction
Hydrolase
Ichthyosis
Iron
Iron-sulfur
Magnesium
Metal-binding
Nucleotide-binding
Nucleus
Polymorphism
Reference proteome
Transcription
Transcription regulation
Ubl conjugation
Xeroderma pigmentosum
modified[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09
[InstanceEdit:111622] Gopinathrao, G, 2004-03-01 18:40:00
[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:2587579] Weiser, JD
[InstanceEdit:3445779] Weiser, JD
[InstanceEdit:4341137] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:6348073] Croft, D
[InstanceEdit:6378953] Croft, D
[InstanceEdit:6410971] Croft, D
[InstanceEdit:6442989] Croft, D
[InstanceEdit:6475007] Croft, D
[InstanceEdit:6507025] Croft, D
[InstanceEdit:6609128] Croft, D
[InstanceEdit:6626660] Croft, D
[InstanceEdit:6633671] Croft, D
[InstanceEdit:6641434] Croft, D
[InstanceEdit:6672501] Croft, D
[InstanceEdit:6688369] Croft, D
[InstanceEdit:6715121] Croft, D
nameERCC2
otherIdentifier0000130577
11735285_x_at
11750082_a_at
11754536_a_at
2068
213468_at
235399_at
32396_f_at
32397_r_at
3865308
3865309
3865312
3865314
3865317
3865318
3865322
3865323
3865326
3865327
3865328
3865331
3865332
3865333
3865334
3865335
3865336
3865337
3865338
3865339
41095_at
63062_at
8037537
992_at
A8MX75
A_23_P130488
A_24_P401990
AAI08256
AAI10524
AAL48323
AAM45142
AAP35529
AY092780
BC108255
BC110523
BT006883
CAA36463
CAA36464
CAB005375
CCDS33049
CCDS46112
CH471126
EAW57341
ENSG00000104884
ENSP00000375809
ENSP00000431229
ENST00000391945
ENST00000485403
EntrezGene:2068
ERCC2
ERCC2-001
ERCC2-006
GE59772
HGNC:3434
HPA038057
Hs.184329.0.S1_3p_at
Hs.487294
Hs.663234
Hs.99987.0.S1_3p_at
ILMN_1815859
IPR001945
IPR006554
IPR006555
IPR010614
IPR010643
IPR013020
IPR014013
IPR027417
K7EIT8
L47234
LRG_461
LRG_461t1
MIM:126340
MIM:278730
MIM:601675
MIM:610756
NM_000400
NM_001130867
NP_000391
NP_001124339
OTTHUMP00000045860
OTTHUMP00000267449
PF06733
PF06777
PH_hs_0005591
PR00852
SM00488
SM00491
TC19002519.hg
uc002pbj.2
uc002pbl.5
UPI000006D9DE
UPI0000139012
X52221
X52221_at
X52222
XM_005258639
XP_005258696
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:6691351] KEGG Gene:2068 excision repair cross-complementation group 2 [Homo sapiens]
[ReferenceDNASequence:6353059] ENSEMBL:ENSG00000104884 [Homo sapiens]
[ReferenceDNASequence:6383902] NCBI Gene:2068 [Homo sapiens]
[ReferenceDNASequence:6416384] BioGPS Gene:2068 [Homo sapiens]
[ReferenceDNASequence:6448402] CTD Gene:2068 [Homo sapiens]
[ReferenceDNASequence:6480420] dbSNP Gene:2068 [Homo sapiens]
[ReferenceDNASequence:6629792] OMIM:278730 [Homo sapiens]
[ReferenceDNASequence:6629793] OMIM:601675 [Homo sapiens]
[ReferenceDNASequence:6629794] OMIM:610756 [Homo sapiens]
[ReferenceDNASequence:6629795] OMIM:126340 [Homo sapiens]
[ReferenceDNASequence:6699528] Orphanet:15989 [Homo sapiens]
referenceTranscript[ReferenceRNASequence:6679522] RefSeq:NM_000400
secondaryIdentifierERCC2_HUMAN
Q2TB78
Q2YDY2
Q7KZU6
Q8N721
sequenceLength760
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:67443] ERCC2 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:2564770] ERCC2 [cytosol] [Homo sapiens]
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