|Affiliation||German Cancer Research Center (DKFZ)|
|Author of summation(s)||A hallmark of the human cell cycle in normal somatic cells i...
In the G1 phase there are two types of DNA damage responses,...
|Author of entries||Cell Cycle Checkpoints [Homo sapiens]
p53-Independent DNA Damage Response [Homo sapiens]
p53-Independent G1/S DNA damage checkpoint [Homo sapiens]
Phosphorylation of Cdc25A at Ser-123 by Chk1 [Homo sapiens]
Phosphorylation of Cdc25A at Ser-123 by Chk2 [Homo sapiens]
Proteolytic degradation of ubiquitinated-Cdc25A [Homo sapiens]
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A [Homo sapiens]
Ubiquitination of phosphorylated Cdc25A [Homo sapiens]
|Publication(s)||Blomberg, I, Hoffmann, I Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases 1999 Mol Cell Biol PubMed
Volkening, M, Hoffmann, I Involvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatin 2005 Mol Cell Biol PubMed
Hoffmann, I, Clarke, PR, Marcote, MJ, Karsenti, E, Draetta, G Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis 1993 EMBO J PubMed