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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
SurnameThompson
First nameL
InitialsL
AffiliationLawrence Livermore National Laboratory
Author of summation(s)
DNA repair is a phenomenal multi-enzyme, multi-pathway syste...
Numerous types of DNA damage can occur within a cell due to ...
The HRR pathway is an "error free" DNA repair mechanism that...
Author of entries
53BP1 associates with gamma H2AX at nuclear foci [Homo sapiens]
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks [Homo sapiens]
Assembly of the RAD51-ssDNA nucleoprotein complex [Homo sapiens]
Association of RPA complexes with ssDNA [Homo sapiens]
Association of gamma-H2AX with NBS1 [Homo sapiens]
Association of MRN with sites of DSB [Homo sapiens]
Association of RAD50:MRE11 complex with NBS1 via MRE11 interaction [Homo sapiens]
Association of RAD51 with BRCA2 [Homo sapiens]
Association of RAD51 with RAD52:DNA double-strand break ends [Homo sapiens]
Association of RAD51 with the RPA complex [Homo sapiens]
Association of RAD52 with the RPA complex [Homo sapiens]
ATM mediated phosphorylation of repair proteins [Homo sapiens]
ATM mediated response to DNA double-strand break [Homo sapiens]
BRCA1 associates with 53BP1at the site of DNA double-strand break [Homo sapiens]
Cleavage of Holliday junctions [Homo sapiens]
Dissociation of dimeric phospho-ATM complexes [Homo sapiens]
Dissociation of the extended strands [Homo sapiens]
DNA Repair [Homo sapiens]
DNA repair synthesis [Homo sapiens]
Double-Strand Break Repair [Homo sapiens]
Fill-in DNA synthesis [Homo sapiens]
Formation of RAD50:MRE11 complex [Homo sapiens]
Formation of RAD52 heptameric ring structure complexes on ssDNA [Homo sapiens]
Homologous DNA pairing and strand exchange [Homo sapiens]
Homologous Recombination Repair [Homo sapiens]
Homologous recombination repair of replication-independent double-strand breaks [Homo sapiens]
Intermolecular autophosphorylation of ATM within dimeric ATM complexes [Homo sapiens]
Ligation of DNA and formation of Holliday structures following repair synthesis [Homo sapiens]
MDC1/NFBD1 associates with gamma H2AX at nuclear foci [Homo sapiens]
MRN complex relocalizes to nuclear foci [Homo sapiens]
phospho-ATM (Serine 1981) associates with DNA at the site of double-strand breaks [Homo sapiens]
Presynaptic phase of homologous DNA pairing and strand exchange [Homo sapiens]
Processing of DNA double-strand break ends [Homo sapiens]
Recruitment of repair and signaling proteins to double-strand breaks [Homo sapiens]
Resection of double-strand break ends [Homo sapiens]
Resolution of D-loop structures [Homo sapiens]
Resolution of D-loop structures through Holliday junction intermediates [Homo sapiens]
Resolution of D-loop structures through synthesis-dependent strand-annealing [Homo sapiens]
Strand exchange/Branch migration [Homo sapiens]
Publication(s)
Thompson, L, Limoli, L Origin, Recognition, Signaling and Repair of DNA Double-Strand Breaks in Mammalian Cells 2003 Damage Surveillance and Repair (Keith Caldecott, editor) Origin, Recognition, Signaling and Repair of DNA Double-Strand Breaks in Mammalian Cells