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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
SurnameMarzluff
First nameWilliam F
InitialsWF
AffiliationUniversity of North Carolina at Chapel Hill
Author of summation(s)
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Co-transcriptional pre-mRNA splicing is not obligatory. Pre-...
Histone mRNAs are exported by a mechanism that requires TAP,...
Histone mRNAs are exported by a mechanism that requires TAP,...
Processing is initiated once the SLBP (bound to the stem loo...
Processing is initiated once the U7 snRNP is loaded onto the...
The 32 kDa stem-loop binding protein (SLBP), also termed hai...
The U7 snRNP. This particle contains the U7 snRNA, the smal...
There are two well-documented trans-acting factors required ...
This class of mRNAs is expressed from genes that lack intron...
Author of entries
Binding of SLBP to Replication-Dependent Histone Pre-mRNA [Homo sapiens]
Cleavage of Growing Transcript in the Termination Region [Homo sapiens]
Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA [Homo sapiens]
Cleavage of the 3'-end of the Histone Pre-mRNA [Homo sapiens]
Docking of Mature Histone mRNA complex:TAP at the NPC [Homo sapiens]
Docking of Mature Replication Dependent Histone mRNA with the NPC [Homo sapiens]
Processing of Capped Intronless Pre-mRNA [Homo sapiens]
Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA [Homo sapiens]
Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA [Homo sapiens]
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs [Homo sapiens]
SLBP independent Processing of Histone Pre-mRNAs [Homo sapiens]
Publication(s)
Dominski, Z, Erkmann, JA, Yang, X, Sanchez, R, Marzluff, WF A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing 2002 Genes Dev PubMed
Dominski, Z, Marzluff, WF Formation of the 3' end of histone mRNA. 1999 Gene PubMed
Harris, ME, Bohni, R, Schneiderman, MH, Ramamurthy, L, Schumperli, D, Marzluff, WF Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps. 1991 Mol Cell Biol PubMed
Dominski, Z, Zheng, LX, Sanchez, R, Marzluff, WF Stem-loop binding protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA. 1999 Mol Cell Biol PubMed
Marzluff, WF, Gongidi, P, Woods, KR, Jin, J, Maltais, LJ The human and mouse replication-dependent histone genes 2002 Genomics PubMed
Wang, ZF, Whitfield, ML, Ingledue, TC, Dominski, Z, Marzluff, WF The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing. 1997 Genes Dev PubMed
Sanchez, R, Marzluff, WF The stem-loop binding protein is required for efficient translation of histone mRNA in vivo and in vitro 2002 Mol Cell Biol PubMed