|First name||Kum Kum|
|Affiliation||Queensland Institute of Medical Research, Signal Transduction Laboratory|
|Author of summation(s)||A hallmark of the human cell cycle in normal somatic cells i...
In the G1 phase there are two types of DNA damage responses,...
The arrest at G1/S checkpoint is mediated by the action of a...
|Author of entries||Cell Cycle Checkpoints [Homo sapiens]
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 [Homo sapiens]
p53-Dependent G1 DNA Damage Response [Homo sapiens]
p53-Dependent G1/S DNA damage checkpoint [Homo sapiens]
Phosphorylation of p53 at ser-15 by ATM kinase [Homo sapiens]
Stabilization of p53 [Homo sapiens]
Transcriptional activation of cell cycle inhibitor p21 [Homo sapiens]
Transcriptional activation of p53 responsive genes [Homo sapiens]
|Publication(s)||Khanna, KK, Keating, KE, Kozlov, S, Scott, S, Gatei, M, Hobson, K, Taya, Y, Gabrielli, B, Chan, D, Lees-Miller, SP, Lavin, MF ATM associates with and phosphorylates p53: mapping the region of interaction. 1998 Nat Genet PubMed
Khanna, KK DNA double-strand breaks: signaling, repair and the cancer connection. 2001 Nat Genet PubMed
Khanna, KK, Lavin, MF Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. 1993 Oncogene PubMed