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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:P35991
DatabaseUniProt
SpeciesMus musculus
DescriptionrecommendedName: Tyrosine-protein kinase BTK ecNumber2.7.10.2/ecNumber alternativeName: Agammaglobulinemia tyrosine kinase shortName:ATK alternativeName: B-cell progenitor kinase shortName:BPK alternativeName: Bruton tyrosine kinase alternativeName: Kinase EMB
Links to corresponding entries in other databasesBioGPS Gene:12229
CTD Gene:12229
ENSEMBL:ENSMUSG00000031264
HapMap:NM_052832
NCBI Gene:12229
PRO:P35991
RefSeq:NM_052832
RefSeq:NP_038510
UniProt:P35991
dbSNP Gene:12229
Other identifiers related to this sequenceBTK_MOUSE, Q61365, 4762549, PF07714, SM00219, AAB47246, PF00779, SM00220, 4806675, 4802352, EntrezGene:12229, 4784619, XM_006528485, ENSMUSP00000033617, A_51_P145883, IPR001245, PR00452, ENSMUSG00000031264, L08967, 5181212, OTTMUSP00000020834, uc009uge.2, 10606694, 5407825, MGI:88216, 4508773, AAA66943, L10627, L29788, PF00018, IPR001452, IPR000719, PR00401, SM00326, 5246001, 5013694, 12229, NM_013482, 4442988, 4686834, 5279770, SM00252, 4928896, PF00017, XP_006528547, 5421704, XP_006528546, IPR002290, IPR011009, XP_006528548, XM_006528483, Btk, 5350754, U58105, PF07653, A_55_P2158498, AAA37316, 1422755_at, Btk-001, l10627_s_at, 4879789, 4663147, CCDS30396, 4797869, 4430992, PF00069, IPR001849, 4888442, 4316340, SM00107, mMC007729, NP_038510, 5038110, 4315801, A_55_P1953819, ILMN_1235934, PR00402, IPR011511, PF00169, 92668_at, GE36959, IPR000980, SM00233, PR00109, XM_006528484, IPR020635, Mm.4475, IPR001562, UPI000002371A, BTK
Molecules with this sequenceBtk [cytosol] UENBCdRHPR
phospho-p-Y223,Y551-BTK [plasma membrane] UENBCdRHPR
phospho-p-Y223,Y551-BTK [cytosol] UENBCdRHPR
phospho-p-Y551-BTK [cytosol] UENBCdRHPR
Component ofactivated TLR2/4:p-4Y-MAL:PI(4,5)P2:BTK (name copied from entity in Homo sapiens) [plasma membrane]
MAL:PI(4,5)P2:BTK:activated TLR2/4 (name copied from entity in Homo sapiens) [plasma membrane]
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV (name copied from entity in Homo sapiens) [plasma membrane]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 (name copied from entity in Homo sapiens) [plasma membrane]
p-BTK:PIP3 (name copied from entity in Homo sapiens) [plasma membrane]
p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK (name copied from entity in Homo sapiens) [plasma membrane]
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG (name copied from entity in Homo sapiens) [plasma membrane]
p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV (name copied from entity in Homo sapiens) [plasma membrane]
MyD88:MAL:BTK:activated TLR2/4 (name copied from entity in Homo sapiens) [plasma membrane]
oligo-MyD88:Mal:BTK:activated TLR (name copied from entity in Homo sapiens) [plasma membrane]
...
List all 27 items
Represented by generalisation(s)Tec kinases [cytosol]
TEC,BTK,ITK,(TXK) [cytosol]
p-SYK,p-BTK [cytosol]
p-2Y-TEC kinases [cytosol]
p-TEC kinases [cytosol]
SYK/BTK [cytosol]
Processes where molecules and complexes with this sequence are involved

Immune System

Modifications in molecules with this sequenceO4'-phospho-L-tyrosine at 223 (in Homo sapiens)
O4'-phospho-L-tyrosine at 551 (in Homo sapiens)
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