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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Details
IdentifierUniProt:O14757
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Serine/threonine-protein kinase Chk1 ecNumber2.7.11.1/ecNumber alternativeName: CHK1 checkpoint homolog alternativeName: Cell cycle checkpoint kinase alternativeName: Checkpoint kinase-1
Links to corresponding entries in other databasesBioGPS Gene:1111
Brenda:2.7.11.1
CTD Gene:1111
DOCK Blaster:1IA8
DOCK Blaster:1NVQ
DOCK Blaster:1NVR
DOCK Blaster:1NVS
DOCK Blaster:1ZLT
DOCK Blaster:2BR1
DOCK Blaster:2BRB
DOCK Blaster:2BRG
DOCK Blaster:2BRH
DOCK Blaster:2BRM
DOCK Blaster:2BRN
DOCK Blaster:2BRO
DOCK Blaster:2C3J
DOCK Blaster:2C3K
DOCK Blaster:2C3L
DOCK Blaster:2CGU
DOCK Blaster:2CGV
DOCK Blaster:2CGW
DOCK Blaster:2CGX
EC:2.7.11.1
ENSEMBL:ENSG00000149554
GeneCards:O14757
HapMap:NM_001274
IntEnz:2.7.11.1
KEGG Gene:1111
NCBI Gene:1111
OMIM:603078
Protein Data Bank:1IA8
Protein Data Bank:1NVQ
Protein Data Bank:1NVR
Protein Data Bank:1NVS
Protein Data Bank:1ZLT
Protein Data Bank:2BR1
Protein Data Bank:2BRB
Protein Data Bank:2BRG
Protein Data Bank:2BRH
Protein Data Bank:2BRM
Protein Data Bank:2BRN
Protein Data Bank:2BRO
Protein Data Bank:2C3J
Protein Data Bank:2C3K
Protein Data Bank:2C3L
Protein Data Bank:2CGU
Protein Data Bank:2CGV
Protein Data Bank:2CGW
Protein Data Bank:2CGX
RefSeq:NM_001274
RefSeq:NP_001265
UCSC human:O14757
UniProt:O14757
dbSNP Gene:1111
Other identifiers related to this sequenceCHK1_HUMAN, A8K934, B4DDD0, B4DSK3, B5BTY6, F5H7S4, H2BI51, ENSG00000149554, ENST00000278916, ENSP00000278916, ENST00000392703, ENSP00000376467, 205393_s_at, 238075_at, 205394_at, 38920_at, 50018_at, g4502802_3p_at, Hs.24529.0.A1_3p_at, A_14_P109041, A_23_P116123, CCDS8459, GE62458, AY304548, AF016582, AF032874, AB032387, AF527555, BC004202, BC017575, EntrezGene:1111, GI_20127419-S, ILMN_25327, IPI00023664, MIM:603078, 1IA8, 1NVQ, 1NVR, 1NVS, 1ZLT, 2BR1, 2BRB, 2BRG, 2BRH, 2BRM, 2BRN, 2BRO, 2C3J, 2C3K, 2C3L, 2CGU, 2CGV, 2CGW, 2CGX, AAQ76038, AAC51736, AAB88852, BAA84577, AAM78553, AAH04202, AAH17575, NM_001274, NP_001265, Hs.24529, Q6W8P8, O14757, Q6W8P8_HUMAN, CHK1_HUMAN, IPR000719, IPR008271, IPR001245
Molecules with this sequenceCHEK1 [nucleoplasm] UKENBCdORHGURPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDD
p-S317,S345-CHEK1 [nucleoplasm] UKENBCdORHGURPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDD
CHEK1 [cytosol] UKENBCdORHGURPPPPPPPPPPPPPPPPPPPDDDDDDDDDDDDDDDDDDD
Component ofTyrosine kinases:p-KIT complex [plasma membrane]
Represented by generalisation(s)Tyrosine kinases [cytosol]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Cell Cycle

Modifications in molecules with this sequenceO-phospho-L-serine at 317
O-phospho-L-serine at 345
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