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Reactome: A Curated Pathway Database
Details
IdentifierUniProt:O14757
DatabaseUniProt
SpeciesHomo sapiens
DescriptionrecommendedName: Serine/threonine-protein kinase Chk1 ecNumber2.7.11.1/ecNumber alternativeName: CHK1 checkpoint homolog alternativeName: Cell cycle checkpoint kinase alternativeName: Checkpoint kinase-1
Links to corresponding entries in other databasesBioGPS Gene:1111
Brenda:2.7.11.1
CTD Gene:1111
DOCK Blaster:1IA8
DOCK Blaster:1NVQ
DOCK Blaster:1NVR
DOCK Blaster:1NVS
DOCK Blaster:1ZLT
DOCK Blaster:2BR1
DOCK Blaster:2BRB
DOCK Blaster:2BRG
DOCK Blaster:2BRH
DOCK Blaster:2BRM
DOCK Blaster:2BRN
DOCK Blaster:2BRO
DOCK Blaster:2C3J
DOCK Blaster:2C3K
DOCK Blaster:2C3L
DOCK Blaster:2CGU
DOCK Blaster:2CGV
DOCK Blaster:2CGW
DOCK Blaster:2CGX
EC:2.7.11.1
ENSEMBL:ENSG00000149554
GeneCards:O14757
HapMap:NM_001274
IntEnz:2.7.11.1
KEGG Gene:1111
NCBI Gene:1111
OMIM:603078
PRO:O14757
Protein Data Bank:1IA8
Protein Data Bank:1NVQ
Protein Data Bank:1NVR
Protein Data Bank:1NVS
Protein Data Bank:1ZLT
Protein Data Bank:2BR1
Protein Data Bank:2BRB
Protein Data Bank:2BRG
Protein Data Bank:2BRH
Protein Data Bank:2BRM
Protein Data Bank:2BRN
Protein Data Bank:2BRO
Protein Data Bank:2C3J
Protein Data Bank:2C3K
Protein Data Bank:2C3L
Protein Data Bank:2CGU
Protein Data Bank:2CGV
Protein Data Bank:2CGW
Protein Data Bank:2CGX
RefSeq:NM_001274
RefSeq:NP_001265
UCSC human:O14757
UniProt:O14757
dbSNP Gene:1111
Other identifiers related to this sequenceCHK1_HUMAN, A8K934, B4DDD0, B4DSK3, B5BTY6, F5H7S4, H2BI51, 4FTO, 2BRB, OTTHUMP00000231301, SM00219, 3JVS, 4FSM, 4FSU, 9382850, 3JVR, 2BRN, 3F9N, IPR001245, CHEK1, 3354818, 2E9N, 3354815, AY304548, AAH17575, CHEK1-002, AB451222, 2E9U, 3354809, 2WMU, 2X8E, 2C3K, 2YM4, UPI000013DBA3, 3PA4, 3354823, 1ZYS, 3354839, BC017575, 2GHG, 4FTK, 2BR1, 2YM8, AF032874, 4FTM, BAG70159, E9PKQ3, 4HYI, 2XF0, 2WMR, BAA84577, IPR011009, 3354828, 2CGV, Hs.24529, 1111, AF527555, 4FT5, AAQ76038, A_33_P3349536, HPA044364, 3354824, NM_001114121, XP_006718822, 2E9P, 2CGU, ENSG00000149554, 2HY0, 4HYH, 1NVQ, 3TKH, 2YM5, 4FT9, PH_hs_0022049, 2WMT, 2YDI, 2CGX, 4FTJ, A_14_P109041, 2BRO, BC004202, 2QHN, 2WMW, 4FSW, Hs.595920, 2BRH, 4FTQ, 4FSY, 3354812, 2YEX, 3354811, 2XEZ, 205393_s_at, E9PJI4, 4FT7, 2BRG, 2YDK, 4FSQ, CCDS8459, 11738250_at, 4FTU, 4FTI, E9PRU7, 3OT8, NP_001107593, 11738251_x_at, 4GH2, AB451345, MIM:603078, 4FST, PF07714, 2X8D, 3354822, SM00220, CAB002049, CH471065, 11745949_x_at, 3354810, uc001qcf.4, AK293143, HGNC:1925, 4FTL, 1NVS, EntrezGene:1111, 2BRM, 2R0U, AAM78553, 3354814, 2E9O, 3PA5, 2C3J, 4FT0, 2YM7, AB032387, 3354826, 1NVR, 2YWP, IPR000719, 9278511, 4FTA, 4FSN, 3TKI, 2YM3, 4FTC, AAH04202, 3354804, 4FTN, 1IA8, 2QHM, 2WMV, 2C3L, 3PA3, 2HXQ, E9PQW7, 16733104, AK292549, A_14_P137119, 3U9N, IPR002290, 4FT3, 2GDO, Q6W8P8, BAG70036, AF016582, AAC51736, 2HOG, BAF85238, NM_001274, 2AYP, 2WMX, 2YER, 2E9V, E9PM65, ENSP00000412504, BAG56691, 2YDJ, 3NLB, 2HXL, AP001132, EAW67644, PF00069, AAB88852, 3354829, 2WMQ, 7945014, 1ZLT, 2CGW, 4FSZ, JF289264, AEB71796, 4FTR, AK299783, 3354813, BAG61665, 4FTT, 4FSR, 3OT3, 2WMS, 2X8I, IPR020635, 4JIK, 2YM6, 2XEY, 11729663_a_at, 3354830, UPI00001FA642, 11745948_a_at, 205394_at, A_23_P116123, CHEK1-005, g4502802_3p_at, 3354803, 3354831, ILMN_1664630, 3354832, OTTHUMP00000275490, 38920_at, uc010sbh.2, ENSP00000442317, 3354834, 3354833, CHEK1-004, 50018_at, 3354805, OTTHUMP00000231306, ENSP00000435371, Hs.24529.0.A1_3p_at, 238075_at, NP_001265, 11759013_at, uc001qcg.4, 3354807, ENSP00000432890, 3354806, uc009zbp.3, 3354808, CHEK1-007, OTTHUMP00000231307, 3354800, 3354802, 3354801, CHEK1-201, uc009zbo.3, NP_001107594, ENSP00000388648, NM_001114122
Molecules with this sequenceCHEK1 [nucleoplasm] UKENBCdORHPGPPPPPPPPPPPPPPPPPPPURDDDDDDDDDDDDDDDDDDD
p-S317,S345-CHEK1 [nucleoplasm] UKENBCdORHPGPPPPPPPPPPPPPPPPPPPURDDDDDDDDDDDDDDDDDDD
CHEK1 [cytosol] UKENBCdORHPGPPPPPPPPPPPPPPPPPPPURDDDDDDDDDDDDDDDDDDD
Component ofTyrosine kinases:p-KIT complex [plasma membrane]
Represented by generalisation(s)Tyrosine kinases [cytosol]
Processes where molecules and complexes with this sequence are involved

Signal Transduction

Cell Cycle

Modifications in molecules with this sequenceO-phospho-L-serine at 317
O-phospho-L-serine at 345
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