instancebrowser | sectioned | sidebarwithdynamichierarchy
Reactome (instancebrowser)
Reactome: A Curated Pathway Database
Class:IdBlackBoxEvent:912503
_displayNameFormation of meiotic single-stranded DNA invasion complex
_doReleaseTRUE
_timestamp2014-09-11 07:17:50
authored[InstanceEdit:913923] May, B, 2010-07-19
compartment[EntityCompartment:7660] nucleoplasm
created[InstanceEdit:912491] May, B, 2010-07-08
edited[InstanceEdit:913923] May, B, 2010-07-19
inferredFrom
input[EntityWithAccessionedSequence:50951] BRCA2 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:62637] RAD51 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:912490] DMC1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:69484] ATM [nucleoplasm] [Homo sapiens]
[Complex:68462] RPA heterotrimer [nucleoplasm] [Homo sapiens]
[OtherEntity:75156] 3' overhanging DNA at resected DSB ends [nucleoplasm]
[EntityWithAccessionedSequence:50949] BRCA1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:113843] CDK4 [nucleoplasm] [Homo sapiens]
[Complex:975775] Nucleosome with Histone H2A.x [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:913210] Temporal progression of recombination in human males
[LiteratureReference:913242] Structure of the hDmc1-ssDNA filament reveals the principles of its architecture
[LiteratureReference:913259] A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments
[LiteratureReference:913251] The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51
[LiteratureReference:913234] Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange
[LiteratureReference:913202] Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1
[LiteratureReference:913318] Analysis of replication protein A (RPA) in human spermatogenesis
[LiteratureReference:83639] Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA.
[LiteratureReference:913262] Distribution of the Rad51 recombinase in human and mouse spermatocytes
[LiteratureReference:265961] Association of BRCA1 with Rad51 in mitotic and meiotic cells
modified[InstanceEdit:913297] May, B, 2010-07-13
[InstanceEdit:914114] May, B, 2010-07-22
[InstanceEdit:914224] May, B, 2010-07-24
[InstanceEdit:975789] May, B, 2010-10-04
[InstanceEdit:1008999] May, B, 2010-11-11
[InstanceEdit:1017214] May, B, 2010-11-16
[InstanceEdit:1086964] May, B, 2010-11-29
[InstanceEdit:1220550] May, B, 2011-02-20
[InstanceEdit:1221624] May, B, 2011-02-25
[InstanceEdit:5255525] May, B, 2014-02-06
[InstanceEdit:5702526] Schmidt, EE
[InstanceEdit:5762839] Schmidt, EE
[InstanceEdit:5820760] Schmidt, EE
[InstanceEdit:5883983] Schmidt, EE
[InstanceEdit:5944311] Schmidt, EE
nameFormation of meiotic single-stranded DNA invasion complex
Formation of Early Recombination Nodule
orthologousEvent
output[Complex:912507] Meiotic single-stranded DNA complex [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2011-03-15
reviewed[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25
[InstanceEdit:1181360] Cohen, PE, 2011-02-04
[InstanceEdit:1181371] Holloway, JK, 2011-02-04
[InstanceEdit:1221625] Lyndaker, A, 2011-02-25
[InstanceEdit:1181380] Schimenti, JC, 2011-02-04
[InstanceEdit:1221623] Strong, E, 2011-02-25
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1224921]
summation[Summation:914103] Two RecA homologs, RAD51 and the meiosis-specific DMC1, coat...
(hasEvent)[Pathway:912446] Meiotic recombination [Homo sapiens]
(inferredFrom)[BlackBoxEvent:5735686] Formation of meiotic single-stranded DNA invasion complex [Sus scrofa]
[BlackBoxEvent:5794075] Formation of meiotic single-stranded DNA invasion complex [Bos taurus]
[BlackBoxEvent:5854381] Formation of meiotic single-stranded DNA invasion complex [Canis familiaris]
[BlackBoxEvent:5977308] Formation of meiotic single-stranded DNA invasion complex [Rattus norvegicus]
(orthologousEvent)[BlackBoxEvent:5735686] Formation of meiotic single-stranded DNA invasion complex [Sus scrofa]
[BlackBoxEvent:5794075] Formation of meiotic single-stranded DNA invasion complex [Bos taurus]
[BlackBoxEvent:5854381] Formation of meiotic single-stranded DNA invasion complex [Canis familiaris]
[BlackBoxEvent:5977308] Formation of meiotic single-stranded DNA invasion complex [Rattus norvegicus]
(precedingEvent)[BlackBoxEvent:912458] Formation of meiotic heteroduplex [Homo sapiens]
(regulatedEntity)[PositiveRegulation:914161] 'TEX15 [nucleoplasm]' positively regulates 'Formation of meiotic single-stranded DNA invasion complex'
[PositiveRegulation:914162] 'RAD51C [nucleoplasm]' positively regulates 'Formation of meiotic single-stranded DNA invasion complex'
(representedInstance)[ReactionVertex:7128463]
[Change default viewing format]