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Reactome (instancebrowser)
Reactome: A Curated Pathway Database
AffiliationUniversity of California San Diego, Department of Pathology & Division of Biological Sciences
Malakhov, MP, Kim, KI, Malakhova, OA, Jacobs, BS, Borden, EC, Zhang, DE High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction 2003 J Biol Chem PubMed
Kim, KI, Giannakopoulos, NV, Virgin, HW, Zhang, DE Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation 2004 Mol Cell Biol PubMed
Malakhova, OA, Zhang, DE ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response 2008 J Biol Chem PubMed
Jeon, YJ, Choi, JS, Lee, JY, Yu, KR, Kim, SM, Ka, SH, Oh, KH, Kim, KI, Zhang, DE, Bang, OS, Chung, CH ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway 2009 EMBO Rep PubMed
Okumura, F, Zou, W, Zhang, DE ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP 2007 Genes Dev PubMed
Zou, W, Papov, V, Malakhova, O, Kim, KI, Dao, C, Li, J, Zhang, DE ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin 2005 Biochem Biophys Res Commun PubMed
Dao, CT, Zhang, DE ISG15: a ubiquitin-like enigma 2005 Front Biosci PubMed
Giannakopoulos, NV, Luo, JK, Papov, V, Zou, W, Lenschow, DJ, Jacobs, BS, Borden, EC, Li, J, Virgin, HW, Zhang, DE Proteomic identification of proteins conjugated to ISG15 in mouse and human cells 2005 Biochem Biophys Res Commun PubMed
Zou, W, Zhang, DE The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase 2006 J Biol Chem PubMed
Malakhov, MP, Malakhova, OA, Kim, KI, Ritchie, KJ, Zhang, DE UBP43 (USP18) specifically removes ISG15 from conjugated proteins 2002 J Biol Chem PubMed
Malakhova, OA, Kim, KI, Luo, JK, Zou, W, Kumar, KG, Fuchs, SY, Shuai, K, Zhang, DE UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity 2006 EMBO J PubMed