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MAP kinase cascade Stable identifier REACT_634.5 Authored Charalambous, M, 2004-04-29 Reviewed Greene, LA, 2007-11-08 Your feedback Let us know what you think of this article (click here) The MAP kinase cascade describes a sequence of phosphorylation events involving serine/threonine-specific protein kinases. Used by various signal transduction pathways, this cascade constitutes a common 'module' in the transmission of an extracellular signal into the nucleus. Organism Homo sapiens Cellular compartment cell GO Represents GO biological process MAPKKK cascade GO Equivalent event(s) in other organism(s) MAP kinase cascade [Canis familiaris] MAP kinase cascade [Bos taurus] MAP kinase cascade [Sus scrofa] MAP kinase cascade [Mus musculus] MAP kinase cascade [Rattus norvegicus] MAP kinase cascade [Gallus gallus] MAP kinase cascade [Taeniopygia guttata] MAP kinase cascade [Xenopus tropicalis] MAP kinase cascade [Danio rerio] MAP kinase cascade [Drosophila melanogaster] MAP kinase cascade [Caenorhabditis elegans] MAP kinase cascade [Arabidopsis thaliana] MAP kinase cascade [Oryza sativa] MAP kinase cascade [Saccharomyces cerevisiae] MAP kinase cascade [Schizosaccharomyces pombe] Participating molecules 14-3-3 protein beta/alpha [cytosol] UKEGBCdORRHHURRPP Activated ERK1 [cytosol] UKEGBCdORHUR Activated ERK2 [cytosol] UKEGBCdORRHHURRPPPDDD ADP [cytosol] CCP ATP [cytosol] CCP ERK1 [cytosol] UKEGBCdORHUR ERK2 [cytosol] UKEGBCdORRHHURRPPPDDD GTP [cytosol] CC MEK [cytosol] MEK1 [cytosol] UKEGBCdORHURPD ... List all 25 participating molecules