Reactome: A Curated Pathway Database
Class:IdReferenceGeneProduct:63994
_chainChangeLogchain:1-691 added on Fri February 6 2015
_displayNameUniProt:Q9Y6L6 SLCO1B1
_timestamp2016-02-24 23:39:13
chainchain:1-691
checksumD13D5130189383A3
commentSIMILARITY Belongs to the organo anion transporter (TC 2.A.60) family.SIMILARITY Contains 1 Kazal-like domain.
crossReference[DatabaseIdentifier:9715776] GeneCards:Q9Y6L6
[DatabaseIdentifier:9773469] PRO:Q9Y6L6
[DatabaseIdentifier:9792907] RefSeq:NP_006437
[DatabaseIdentifier:9837556] UCSC human:Q9Y6L6
[DatabaseIdentifier:11010702] HMDB_protein:HMDBP00454
descriptionrecommendedName: Solute carrier organic anion transporter family member 1B1 alternativeName: Liver-specific organic anion transporter 1 shortName:LST-1 alternativeName: OATP-C alternativeName: Sodium-independent organic anion-transporting polypeptide 2 shortName:OATP-2 alternativeName: Solute carrier family 21 member 6
geneNameSLCO1B1
LST1
OATP1B1
OATP2
OATPC
SLC21A6
identifierQ9Y6L6
isSequenceChangedFALSE
keywordCell membrane
Complete proteome
Disulfide bond
Glycoprotein
Ion transport
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport
modified[InstanceEdit:84067] Schmidt, EE, 2003-12-18 04:29:09
[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:3445779] Weiser, JD
[InstanceEdit:4341137] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:5691543] Weiser, JD
[InstanceEdit:9585445] Croft, D
[InstanceEdit:9609708] Croft, D
[InstanceEdit:9633970] Croft, D
[InstanceEdit:9658232] Croft, D
[InstanceEdit:9682494] Croft, D
[InstanceEdit:9706561] Croft, D
[InstanceEdit:9745126] Croft, D
[InstanceEdit:9773795] Croft, D
[InstanceEdit:9810776] Croft, D
[InstanceEdit:9828341] Croft, D
[InstanceEdit:10995712] Croft, D
[InstanceEdit:11008109] Croft, D
nameSLCO1B1
otherIdentifier10599
11739848_at
210366_at
35570_at
A0A024RAU7
A_14_P114848
AAD38323
AAF20212
AAI14377
AAX20114
AB026257
AF060500
AF205071
AJ132573
AJ400749
AJ400750
AJ400751
AJ400752
AJ400753
AJ400754
AJ400755
AJ400756
AJ400757
AJ400758
AJ400759
AJ400760
AJ400761
AJ400762
AK312970
AY945934
BAA78639
BAG35809
BC114376
CAB62577
CAB97007
CCDS8685
CH471094
EAW96420
EAW96421
ENSG00000134538
ENSP00000256958
ENST00000256958
EntrezGene:10599
g5006264_3p_at
GE55225
HGNC:10959
HPA050892
ILMN_1771118
IPR002350
IPR004156
IPR020846
LRG_1022
LRG_1022t1
MIM:604843
NM_006446
NP_006437
OTTHUMP00000239999
PF03137
PF07648
PH_hs_0038723
R-HSA-1430728
R-HSA-159418
R-HSA-1643685
R-HSA-194068
R-HSA-382551
R-HSA-425397
R-HSA-425407
R-HSA-556833
R-HSA-5619102
R-HSA-5619110
R-HSA-5619115
R-HSA-5661182
R-HSA-879518
SLCO1B1
SLCO1B1-001
uc001req.5
UPI0000043BED
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:11008076] KEGG Gene:SLCO1B1 [Homo sapiens]
[ReferenceDNASequence:9580915] Orphanet:19458 [Homo sapiens]
[ReferenceDNASequence:9595812] NCBI Gene:10599 [Homo sapiens]
[ReferenceDNASequence:9633765] BioGPS Gene:10599 [Homo sapiens]
[ReferenceDNASequence:9658027] CTD Gene:10599 [Homo sapiens]
[ReferenceDNASequence:9682289] dbSNP Gene:10599 [Homo sapiens]
[ReferenceDNASequence:9692617] ENSEMBL:ENSG00000134538 [Homo sapiens]
referenceTranscript[ReferenceRNASequence:9828038] RefSeq:NM_006446
secondaryIdentifierSO1B1_HUMAN
B2R7G2
Q29R64
Q9NQ37
Q9UBF3
Q9UH89
sequenceLength691
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:194133] SLCO1B1 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5661185] SLCO1B1 R580* [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5661200] SLCO1B1 R253* [plasma membrane] [Homo sapiens]
(referenceSequence)[ReplacedResidue:5661180] L-arginine 253 replaced with unknown
[ReplacedResidue:5661207] L-arginine 580 replaced with unknown