Reactome: A Curated Pathway Database
All 6 results
Pathways (4) Reactions (1) Proteins (1) Others (0)
Protein: UniProt:P41440 SLC19A1 (Homo sapiens)
Last changed: 2015-03-12 14:00:50

Pathway: Metabolism (Homo sapiens)
Metabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as the inactivation and elimination of toxic ones generated endogenously or present in the extracellular environment. The processes of energy metabolism can be classified into two groups according to whether the
Last changed: 2015-03-06 23:15:47

Pathway: Metabolism of vitamins and cofactors (Homo sapiens)
Vitamins are a diverse group of organic compounds, required in small amounts in the diet. They have distinct biochemical roles, often as coenzymes, and are either not synthesized or synthesized only in limited amounts by human cells. Vitamins are classified according to their solubility, either fat-soluble or water-soluble. The physiological processes dependent on vitamin-requiring reactions include ma
Last changed: 2015-03-06 23:15:47

Pathway: Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Vitamins are a diverse group of organic compounds, required in small amounts in the diet. They have distinct biochemical roles, often as coenzymes, and are either not synthesized or synthesized only in limited amounts by human cells. Vitamins are classified according to their solubility, either fat-soluble or water-soluble. The physiological processes dependent on vitamin-requiring reactions include ma
Last changed: 2015-03-06 23:15:47

Reaction: Extracellular 5-methyltetrahydrofolate import across the plasma membrane (Homo sapiens)
SLC19A1 protein, associated with the plasma membrane, mediates the uptake of extracellular 5-methyltetrahydrofolate and other reduced folates (Williams and Flintoff 1995; Ferguson and Flintoff 1999)
Last changed: 2015-03-06 18:40:03

Pathway: Metabolism of folate and pterines (Homo sapiens)
Folates are essential cofactors that provide one-carbon moieties in various states of reduction for biosynthetic reactions. Processes annotated here include transport reactions by which folates are taken up by cells and moved intracellularly, folate conjugation with glutamate (required for folate retention within a cell), and some of the key reactions in the generation of reduced folates and one-carbon
Last changed: 2015-03-06 23:15:47