Reactome: A Curated Pathway Database
Results 1 to 10 of 109
Pathways (26) Reactions (42) Proteins (2) Others (39)
Protein: UniProt:P02647 APOA1 (Homo sapiens)
Last changed: 2015-03-12 12:55:37

Pathway: Transmembrane transport of small molecules (Homo sapiens)
Last changed: 2015-03-06 23:15:47

Pathway: Vesicle-mediated transport (Homo sapiens)
Last changed: 2015-03-06 23:15:47

Pathway: Disease (Homo sapiens)
Biological processes are captured in Reactome by identifying the molecules (DNA, RNA, protein, small molecules) involved in them and describing the details of their interactions. From this molecular viewpoint, human disease pathways have three mechanistic causes: the inclusion of microbially-expressed proteins, altered functions of human proteins, or changed expression levels of otherwise functionally
Last changed: 2015-03-06 23:15:47

Pathway: Signal Transduction (Homo sapiens)
Signal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such as hormones and growth factors, or reacting to other types of stimuli, such as light. Stimulation of transmembrane receptors leads to their conformational change which propagates the signal to the intracellu
Last changed: 2015-03-06 23:15:47

Pathway: Metabolism (Homo sapiens)
Metabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as the inactivation and elimination of toxic ones generated endogenously or present in the extracellular environment. The processes of energy metabolism can be classified into two groups according to whether the
Last changed: 2015-03-06 23:15:47

Pathway: Hemostasis (Homo sapiens)
Hemostasis is a physiological response that culminates in the arrest of bleeding from an injured vessel. Under normal conditions the vascular endothelium supports vasodilation, inhibits platelet adhesion and activation, suppresses coagulation, enhances fibrin cleavage and is anti-inflammatory in character. Under acute vascular trauma, vasoconstrictor mechanisms predominate and the endothelium becomes p
Last changed: 2015-03-06 23:15:47

Gene: ENSEMBL:ENSG00000118137 APOA1 (Homo sapiens)
Last changed: 2014-11-24 10:42:05

Reaction: Expression of APOA1 (Homo sapiens)
The APOA1 gene is transcribed to yield mRNA and the mRNA is translated to yield protein
Last changed: 2014-11-24 10:52:25

Pathway: Amyloids (Homo sapiens)
Amyloid is a term used to describe typically extracellular deposits of aggregated proteins, sometimes known as plaques. Abnormal accumulation of amyloid is amyloidosis, a term associated with diseased organs and tissues, particularly neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntingdon's. Amyloid deposits consist predominantly of amyloid fibrils, rigid, non-branching structures th
Last changed: 2015-01-23 11:56:29

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