Reactome: A Curated Pathway Database
All 5 results
Pathways (3) Reactions (1) Proteins (1) Others (0)
Protein: UniProt:P06276 BCHE (Homo sapiens)
Last changed: 2015-03-12 14:00:50

Pathway: Metabolism of proteins (Homo sapiens)
Protein metabolism comprises the pathways of translation, post-translational modification and protein folding
Last changed: 2015-03-06 23:15:47

Pathway: Peptide hormone metabolism (Homo sapiens)
Peptide hormones are cleaved from larger precursors in the secretory system (endoplasmic reticulum, Golgi apparatus, secretory granules) of the cell. After secretion peptide hormones are modified and degraded by extracellular proteases
Last changed: 2015-03-06 23:15:47

Pathway: Synthesis, secretion, and deacylation of Ghrelin (Homo sapiens)
Ghrelin is a peptide hormone of 28 amino acid residues which is acylated at the serine-3 of the mature peptide. Ghrelin is synthesized in several tissues: X/A-like cells of the gastric mucosa (the major source of ghrelin), hypothalamus, pituitary, adrenal gland, thyroid, breast, ovary, placenta, fallopian tube, testis, prostate, liver, gall bladder, pancreas, fat tissue, human lymphocytes, spleen, kidn
Last changed: 2015-03-06 02:57:18

Reaction: Butyrylcholinesterase and Platelet-activating factor acetylhydrolase hydrolyze acyl Ghrelin (Homo sapiens)
The majority of circulating ghrelin is not acylated (des-acyl ghrelin). Acyl ghrelin can be deacylated in the bloodstream by butyrylcholinesterase and platelet-activating factor acetylhydrolase, which are associated with circulating lipids. Other enzymes may also have this capability. It is unknown if a portion of des-acyl ghrelin in the bloodstream is generated by direct synthesis and secretion
Last changed: 2015-03-06 02:57:18