Reactome: A Curated Pathway Database
All 5 results
Pathways (3) Reactions (1) Proteins (1) Others (0)
Protein: UniProt:P51795 CLCN5 (Homo sapiens)
Last changed: 2014-11-26 10:20:21

Pathway: Transmembrane transport of small molecules (Homo sapiens)
Last changed: 2014-11-21 19:49:01

Pathway: Ion channel transport (Homo sapiens)
Ion channels mediate the flow of ions across the plasma membrane of cells. They are integral membrane proteins, typically a multimer of proteins, which, when arranged in the membrane, create a pore for the flow of ions. There are different types of ion channels. P-type ATPases undergo conformational changes to translocate ions. Ligand-gated ion channels operate like a gate, opened or closed by a chemic
Last changed: 2014-11-21 19:49:01

Pathway: Stimuli-sensing channels (Homo sapiens)
Ion channels that mediate sensations such as pain, warmth, cold, taste pressure and vision. Channels that mediate these sensations include acid-sensing ion channels (ASICs) (Wang & Xu 2011, Qadri et al. 2012, Deval et al. 2010) and the transient receptor potential channels (TRPCs) (Takahashi et al. 2012, Numata et al. 2011 in "TRP Channels" Zhu, MX editor, CRC Press, 2011, Ramsey et al. 2006, Montell 2
Last changed: 2014-11-21 19:49:01

Reaction: CLCN4/5/6 exchange Cl- for H+ (Homo sapiens)
The H+/Cl- exchange transporters CLCN4 (Kawasaki et al. 1999, Zdebik et al. 2008), CLCN5 (Zdebik et al. 2008) and CLCN6 (Neagoe et al. 2010) mediate the exchange of endosomal Cl- for cytosolic H+ across endosomal membranes, contributing to the acidification of endosomes
Last changed: 2014-11-21 19:49:01